Patents by Inventor Jaroslav Riha

Jaroslav Riha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITIONS WITH LOW AMOUNTS OF NITROSAMINE IMPURITIES AND METHODS FOR PRODUCING THE SAME
    Publication number: 20230390221
    Abstract: The present invention relates to pharmaceutical compositions comprising metformin with low amounts of nitrosamine impurities and methods for producing the same. More specifically, the present invention relates to methods and compositions that reduce the amount of nitrosable compounds in the active pharmaceutical ingredient and/or reduce the conversion of nitrosable compounds into nitrosamines in the finished dosage form.
    Type: Application
    Filed: October 15, 2021
    Publication date: December 7, 2023
    Applicant: Zentiva K.S.
    Inventors: Jaroslav RIHA, Ludek RIDVAN, Michal DOUSA, Tomas KUBELKA, Petr GIBALA, Frantisek BARTACEK, Pawel STASIAK, Stanislav KALASEK, Anna Kluk, Vít Zvonícek
  • METHOD OF MANUFACTURE OF COMPRESSED PHARMACEUTICAL FORMULATION CONTAINING TIBOLONE
    Publication number: 20100261692
    Abstract: Method of manufacture of compressed pharmaceutical formulation with the active substance tibolone by direct compression into tablets, whereas during the manufacturing process the formulation is subjected to the action of a protic solvent, either by addition of 0.1 to 3% by weight of said solvent in the liquid state and/or in the vapor form by ensuring the ambient atmosphere with the contents of solvent vapors above 50% relative.
    Type: Application
    Filed: July 23, 2008
    Publication date: October 14, 2010
    Inventors: Jaroslav Riha, Jaroslav Rezac, Jan Muzikar, Rudolf Gomola, Vaclav Tomasek, Miroslav Trcka