Patents by Inventor JAROSLAV TRUKSA

JAROSLAV TRUKSA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3,5-BIS(PHENYL)-1H-HETEROARYL DERIVATIVES AS MEDICAMENTS
    Publication number: 20220251124
    Abstract: Compounds of general formula I are disclosed. The meaning of individual substituents is described in the claims. The compounds are useful in treatment of cancers, due to their multi-modal mechanism of action.
    Type: Application
    Filed: June 11, 2020
    Publication date: August 11, 2022
    Applicants: INSTITUTE OF BIOTECHNOLOGY CAS, V.V.I., SMART BRAIN S.R.O.
    Inventors: Jaroslav TRUKSA, Lukas WERNER, Jan STURSA, Kristyna BLAZKOVA, Cristian Adrian SANDOVAL ACUNA
  • DEFEROXAMINE DERIVATIVES AS MEDICAMENTS
    Publication number: 20200078379
    Abstract: The deferoxamine derivatives of general formula I and pharmaceutically acceptable salts thereof, at least one of R1 and R2 is a substituent of formula II. The novel derivatives are particularly suitable as medicaments, preferably for the treatment of cancer. Pharmaceutical preparations of compounds of formula I and a metal, preferably gallium, are also provided resulting in even more active medicaments or contrast agents. Combinations with other agents, resulting in synergistic effects are provided.
    Type: Application
    Filed: July 13, 2018
    Publication date: March 12, 2020
    Applicants: BIOTECHNOLOGICKY USTAV AV CR, V.V.I, SMART BRAIN S.R.O.
    Inventors: JAROSLAV TRUKSA, Lukas WERNER, Jan STURSA