Abstract: Methods of applying and combining cleaning solvent with titanate adhesion promoter to a polymeric substrate are disclosed. In one embodiment, method of applying the solvent mixture includes providing a polymeric substrate to be treated. The polymeric substrate is treated with the reactivation solution comprising a cleaning agent and a titanate adhesion promoter. The reactivation solution is applied to the polymeric substrate and allowed to treat the polymeric substrate by simultaneously cleaning and promoting adhesion, reactivating the surface in preparation for adhesion between the substrate and another material. Finally, another material is applied to the treated polymeric substrate and the method is repeated, if desired. Embodiments of the invention provide the desired production and labor efficiency, while further addressing the risk to personnel in treating a variety of polymeric substrates.