Abstract: Disclosed herein, in certain embodiments, are recombinant PNMA2 and endogenous Gag polypeptides, capsids comprising the recombinant PNMA2 or endogenous Gag polypeptides, and methods of making and using recombinant PNMA2 and endogenous Gag polypeptides.

Abstract: A docking station for a medical device is described. In some examples, the docking station includes a frame and a base plate coupled to the frame. At least a portion of the base plate is coupled to a lower portion of the frame. In some examples, an electronic connector of the docking station is configured to couple to the medical device and to provide power to the medical device when the medical device is docked to the docking station. In some examples, a docking mechanism is coupled to an upper portion of the frame and configured to retain the medical device.

Abstract: A carriage for conveyance of a coil of ferromagnetic metal includes a base portion having a carrier supporting, a suspension mechanism, and a cradle portion, supported relative to the base portion by the suspension mechanism, the cradle portion having a magnetic saddle for engaging the coil of ferromagnetic metal.

Abstract: A carriage for conveyance of a coil of ferromagnetic metal includes an base portion having a carrier supporting, a suspension mechanism, and a cradle portion, supported relative to the base portion by the suspension mechanism, the cradle portion having a magnetic saddle for engaging the coil of ferromagnetic metal.

Abstract: Heart rhythm status information can be provided to a user, including providing a normal heart rhythm indication if detected electrocardiogram data is indicative of a normal heart rhythm, providing an abnormal heart rhythm indication if detected electrocardiogram data is indicative of an abnormal heart rhythm. Further, a current heart rhythm can be recorded, including recording the current heart rhythm in response to the provided abnormal heart rhythm indication if an abnormal heart rhythm indication is provided in response to the first query command, and recording the current heart rhythm in response to a second patient-initiated query command from the user-interface device following a normal heart rhythm indication in response to the first query command.

Abstract: Heart rhythm status information can be provided to a user, including providing a normal heart rhythm indication if detected electrocardiogram data is indicative of a normal heart rhythm, providing an abnormal heart rhythm indication if detected electrocardiogram data is indicative of an abnormal heart rhythm. Further, a current heart rhythm can be recorded, including recording the current heart rhythm in response to the provided abnormal heart rhythm indication if an abnormal heart rhythm indication is provided in response to the first query command, and recording the current heart rhythm in response to a second patient-initiated query command from the user-interface device following a normal heart rhythm indication in response to the first query command.

Abstract: A handheld cardiac rhythm management device for use by a patient to request status information from an implantable pulse generating device and to request that the pulse generating device provide a rhythm altering shock to the patient's heart. The device includes a plurality of deadfront status indicator lamps on a front of a case that are visible to the patient when the controller is held in the patient's hand. The device also includes buttons on the front of the case and a telemetry circuit for bi-directional communication with the implantable pulse generating device.

Abstract: The present invention relates to a wireless handheld device that is configured to communicate with an implanted device using inductive telemetry. The handheld device is preferably battery operated and includes a battery powered controller and a battery powered inductive coil. The inductive coil is configured to communicate with an inductive coil of the implanted device using inductive telemetry. The handheld device may include one battery voltage source that powers both the controller and the inductive coil, or multiple battery voltage sources to power the controller and inductive coil separately. In a single battery voltage source embodiment, the voltage may be amplified or reduced to meet the power needs of the controller and inductive coil. In a multiple battery voltage source embodiment, the voltage sources may be combined to increase the power output requirements of the inductive coil.

Abstract: A handheld cardiac rhythm management device for use by a patient to request status information from an implantable pulse generating device and to request that the pulse generating device provide a rhythm altering shock to the patient's heart. The device includes a plurality of deadfront status indicator lamps on a front of a case that are visible to the patient when the controller is held in the patient's hand. The device also includes buttons on the front of the case and a telemetry circuit for bi-directional communication with the implantable pulse generating device.

Abstract: The present invention relates to a method and apparatus for programming a wireless handheld device and communicating between the handheld device and a programmer using inductive telemetry. The method may include the steps of activating a boot load mode of the handheld device, positioning the handheld device in proximity to a programming device, and downloading firmware to the handheld device from the programming device using inductive telemetry. The apparatus may include an inductive coil for inductive telemetry and a memory. The inductive coil is configured to be activated in response to inductive signals from an inductive coil of the programmer, thereby providing communication between the handheld device and the programmer. Communication between the handheld device and the programmer may include downloading firmware to the handheld device, and storing the downloaded firmware in the memory.

Abstract: A handheld cardiac rhythm management device for use by a patient to request status information from an implantable pulse generating device and to request that the pulse generating device provide a rhythm altering shock to the patient's heart. The device includes a plurality of deadfront status indicator lamps on a front of a case that are visible to the patient when the controller is held in the patient's hand. The device also includes buttons on the front of the case and a telemetry circuit for bi-directional communication with the implantable pulse generating device.