Patents by Inventor Jason B. Shear

Jason B. Shear has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8257967
    Abstract: A system for the rapid characterization of multi-cardiovascular risk factor analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member, in which a plurality of cavities may be formed. A series of chemically sensitive particles, in one embodiment, are positioned within the cavities. The particles may produce a signal when a receptor, coupled to the particle, interacts with the cardiovascular risk factor analyte and the particle-analyte complex is visualized using a visualization reagent. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. In an embodiment, each cavity of the plurality of cavities is designed to capture and contain a specific size particle. Flexible projections may be positioned over each of the cavities to provide retention of the particles in the cavities.
    Type: Grant
    Filed: April 28, 2003
    Date of Patent: September 4, 2012
    Assignee: Board of Regents, The University of Texas System
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Nick J. Christodoulides
  • Publication number: 20110251075
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Application
    Filed: November 5, 2010
    Publication date: October 13, 2011
    Applicant: Board of Regents, The University of Texas System
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk
  • Publication number: 20100290016
    Abstract: According to certain embodiments, systems comprising an energy source; at least one conjugate mask; a magnification device; and a fabrication material; wherein the at least one conjugate mask is disposed between the energy source and the magnification device; and wherein the fabrication material is disposed operable to the magnification device. According to other embodiments, methods and composition employing such systems.
    Type: Application
    Filed: January 2, 2009
    Publication date: November 18, 2010
    Inventors: Bryan Kaehr, Rex Nielson, Jason B. Shear
  • Publication number: 20100075393
    Abstract: The present invention is an apparatus, system and method for forming nanoscale architectures having nanoparticles bound thereto. The present invention provides a photon beam crosslinked polymer matrix, wherein the crosslinked matrix includes one or more polymers crosslinked to one or more crosslinking agents and one or more protein-coated metal nanoparticles.
    Type: Application
    Filed: May 23, 2006
    Publication date: March 25, 2010
    Applicant: Board of Regents,The University of Texas System
    Inventors: Jason B. Shear, Keith J. Stevenson, Ryan T. Hill, Jennifer L. Lyon
  • Patent number: 7651868
    Abstract: A system for the rapid characterization of analytes in saliva. In one embodiment, a system for detecting analytes includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member, in which a plurality of cavities may be formed. A series of chemically sensitive particles, in one embodiment, are positioned within the cavities. The particles may produce a signal when a receptor, coupled to the particle, interacts with the cardiovascular risk factor analyte and the particle-analyte complex is visualized using a visualization reagent. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. In an embodiment, each cavity of the plurality of cavities is designed to capture and contain a specific size particle. Flexible projections may be positioned over each of the cavities to provide retention of the particles in the cavities.
    Type: Grant
    Filed: December 13, 2004
    Date of Patent: January 26, 2010
    Assignee: The Board of Regents of The University of Texas System
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Nick J. Christodoulides
  • Publication number: 20090258791
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Application
    Filed: February 17, 2009
    Publication date: October 15, 2009
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk
  • Publication number: 20090215646
    Abstract: Methods and systems for detecting the presence of analytes are described. A fluid or gas sample containing one or more analytes may pass through a particle-based sensor array. Detection and analysis techniques may be applied to determine the identity and quantity of the analytes.
    Type: Application
    Filed: June 30, 2006
    Publication date: August 27, 2009
    Inventors: Eric V. Anslyn, John T. McDevitt, Jason B. Shear, Dean P. Neikirk, Aaron T. Wright, Zhenlin Zhong
  • Patent number: 7491552
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Grant
    Filed: January 20, 2005
    Date of Patent: February 17, 2009
    Assignee: The Board of Regents of The University of Texas System
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk
  • Publication number: 20090035745
    Abstract: Systems and methods for site-specific dosing of cellular cultures are provided. Some of the systems provided comprise at least two laminar flow channels; and an ablatable membrane that is disposed between the at least two laminar flow channels. Other systems provided comprise at least two laminar flow channels; and an ablated membrane that is disposed between the at least two laminar flow channels. Some of the methods provided comprise providing at least two laminar flow channels; providing a membrane disposed between the at least two laminar flow channels, wherein the membrane is selected from the group consisting of an ablatable membrane and an ablated membrane; placing cells into at least one of the at least two laminar flow channels; providing a reagent medium; and flowing the reagent medium through at least one other of the at least two laminar flow channels.
    Type: Application
    Filed: August 4, 2008
    Publication date: February 5, 2009
    Inventors: Jason B. Shear, Rex Nielson
  • Publication number: 20080219891
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Application
    Filed: January 8, 2008
    Publication date: September 11, 2008
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk
  • Patent number: 7316899
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: January 8, 2008
    Assignee: The Board of Regents of The University of Texas System
    Inventors: John T McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk
  • Patent number: 7022517
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: April 4, 2006
    Assignee: Board of Regents, The University of Texas System
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Damon V. Borich
  • Patent number: 6908770
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Grant
    Filed: April 7, 1999
    Date of Patent: June 21, 2005
    Assignee: Board of Regents, The University of Texas System
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk
  • Patent number: 6713298
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: March 30, 2004
    Assignee: Board of Regents, The University of Texas System
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk
  • Publication number: 20040053322
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Application
    Filed: January 31, 2001
    Publication date: March 18, 2004
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk
  • Publication number: 20040029259
    Abstract: A system for the rapid characterization of multi-cardiovascular risk factor analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member, in which a plurality of cavities may be formed. A series of chemically sensitive particles, in one embodiment, are positioned within the cavities. The particles may produce a signal when a receptor, coupled to the particle, interacts with the cardiovascular risk factor analyte and the particle-analyte complex is visualized using a visualization reagent. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. In an embodiment, each cavity of the plurality of cavities is designed to capture and contain a specific size particle. Flexible projections may be positioned over each of the cavities to provide retention of the particles in the cavities.
    Type: Application
    Filed: April 28, 2003
    Publication date: February 12, 2004
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk, Nick J. Christodoulides
  • Patent number: 6680206
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Grant
    Filed: July 16, 1999
    Date of Patent: January 20, 2004
    Assignee: Board of Regents, The University of Texas System
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk
  • Patent number: 6649403
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: November 18, 2003
    Assignee: Board of Regents, The University of Texas Systems
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk
  • Publication number: 20030186228
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Application
    Filed: January 31, 2001
    Publication date: October 2, 2003
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk
  • Patent number: 6602702
    Abstract: A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: August 5, 2003
    Assignee: The University of Texas System
    Inventors: John T. McDevitt, Eric V. Anslyn, Jason B. Shear, Dean P. Neikirk