Patents by Inventor Jason C. O'Neill

Jason C. O'Neill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VARIANTS OF TISSUE INHIBITOR OF METALLOPROTEINASE TYPE THREE (TIMP-3), COMPOSITIONS AND METHODS
    Publication number: 20220089689
    Abstract: There are disclosed TIMP-3 muteins, variants and derivatives, nucleic acids encoding them, and methods of making and using them.
    Type: Application
    Filed: October 1, 2021
    Publication date: March 24, 2022
    Applicant: AMGEN INC.
    Inventors: Jason C. O'NEILL, Randal R. KETCHEM, TaeWeon LEE, Vishnu CHINTALGATTU, Jennitte LeAnn STEVENS
  • HUMAN IL-23 ANTIGEN BINDING PROTEINS
    Publication number: 20220056122
    Abstract: Antigen binding proteins that bind to human IL-23 protein arc provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes arc also provided.
    Type: Application
    Filed: November 12, 2021
    Publication date: February 24, 2022
    Inventors: Jennifer E. Towne, Janet D. Cheng, Jason C. O'Neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randel R. Ketchem
  • Variants of tissue inhibitor or metalloprotienase type three (TIMP-3), compositions and methods
    Patent number: 11149078
    Abstract: The application concerns tissue inhibitor of metalloproteinase 3 (TIMP-3) muteins, variants and derivatives, nucleic acids encoding them, and methods of making and using them; in particular, muteins of TIMP-3 with specific amino acid substitutions in order to introduce N-linked glycosylation sites.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: October 19, 2021
    Assignee: Amgen Inc.
    Inventors: Jason C. O'Neill, Randal R. Ketchem, Taeweon Lee, Vishnu Chintalgattu, Jennitte Leann Stevens
  • Human IL-23 Antigen Binding Proteins
    Publication number: 20210230267
    Abstract: Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
    Type: Application
    Filed: April 13, 2021
    Publication date: July 29, 2021
    Inventors: Jennifer E. Towne, Janet D. Cheng, Jason C. O'Neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randal R. Ketchem
  • HUMAN IL-23 ANTIGEN BINDING PROTEINS
    Publication number: 20210024626
    Abstract: Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
    Type: Application
    Filed: October 1, 2020
    Publication date: January 28, 2021
    Inventors: Jennifer E. Towne, Janet D. Cheng, Jason C. O'Neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randal R. Ketchem
  • Human IL-23 Antigen Binding Proteins
    Publication number: 20200181255
    Abstract: Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
    Type: Application
    Filed: February 18, 2020
    Publication date: June 11, 2020
    Inventors: Jennifer E. Towne, Janet D. Cheng, Jason C. O'Neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randal R. Ketchem
  • HUMAN IL-23 ANTIGEN BINDING PROTEINS
    Publication number: 20190322737
    Abstract: Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
    Type: Application
    Filed: June 26, 2019
    Publication date: October 24, 2019
    Inventors: Jennifer E. Towne, Janet D. Cheng, Jason C. O'Neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randal R. Ketchem
  • Human IL-23 Antigen Binding Proteins
    Publication number: 20190071498
    Abstract: Antigen binding proteins that bind to human IL-23 protein arc provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes arc also provided.
    Type: Application
    Filed: November 19, 2018
    Publication date: March 7, 2019
    Inventors: Jennifer E. Towne, Janet D. Cheng, Jason C. O'Neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randal R. Ketchem
  • Human IL-23 antigen binding proteins
    Patent number: 9951129
    Abstract: Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: April 24, 2018
    Assignee: AMGEN INC.
    Inventors: Jennifer E. Towne, Janet D. Cheng, Jason C. O'Neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randal R. Ketchem
  • VARIANTS OF TISSUE INHIBITOR OR METALLOPROTIENASE TYPE THREE (TIMP-3), COMPOSITIONS AND METHODS
    Publication number: 20180030116
    Abstract: The application concerns tissue inhibitor of metalloproteinase 3 (TIMP-3) muteins, variants and derivatives, nucleic acids encoding them, and methods of making and using them; in particular, muteins of TIMP-3 with specific amino acid substitutions in order to introduce N-linked glycosylation sites.
    Type: Application
    Filed: August 26, 2015
    Publication date: February 1, 2018
    Inventors: Jason C. O'Neill, Randal R. Ketchem, Taeweon Lee, Vishnu Chintalgattu, Jennitte Leann Stevens
  • GITR ANTIGEN BINDING PROTEINS
    Publication number: 20170022285
    Abstract: Antigen binding proteins that activate GITR are provided. Nucleic acids encoding the antigen binding proteins and vectors and cells containing such nucleic acids are also provided. The antigen binding proteins have value in therapeutic methods in which it is useful to stimulate GITR signaling, thereby inducing or enhancing an immune response in a subject. Accordingly, the antigen binding proteins have utility in a variety of immunotherapy treatments, including treatment of various cancers and infections.
    Type: Application
    Filed: October 10, 2016
    Publication date: January 26, 2017
    Applicant: AMGEN INC.
    Inventors: Courtney BEERS, Jason C. O'NEILL, Ian FOLTZ, Randall R. KETCHEM, Julia C. PIASECKI
  • HUMAN IL-23 ANTIGEN BINDING PROTEINS
    Publication number: 20170002070
    Abstract: Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
    Type: Application
    Filed: September 21, 2016
    Publication date: January 5, 2017
    Inventors: Jennifer E. Towne, Janet D. Cheng, Jason C. O'Neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randal R. Ketchem
  • Human IL-23 antigen binding proteins
    Patent number: 9487580
    Abstract: Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: November 8, 2016
    Assignee: AMGEN INC.
    Inventors: Jennifer E. Towne, Janet D. Cheng, Jason C. O'neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randal R. Ketchem
  • GITR antigen binding proteins and methods of use thereof
    Patent number: 9464139
    Abstract: Antigen binding proteins that activate GITR are provided. Nucleic acids encoding the antigen binding proteins and vectors and cells containing such nucleic acids are also provided. The antigen binding proteins have value in therapeutic methods in which it is useful to stimulate GITR signaling, thereby inducing or enhancing an immune response in a subject. Accordingly, the antigen binding proteins have utility in a variety of immunotherapy treatments, including treatment of various cancers and infections.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: October 11, 2016
    Assignee: AMGEN INC.
    Inventors: Courtney Beers, Jason C. O'Neill, Ian Foltz, Randal R. Ketchem, Julia C. Piasecki
  • GITR ANTIGEN BINDING PROTEINS
    Publication number: 20150064204
    Abstract: Antigen binding proteins that activate GITR are provided. Nucleic acids encoding the antigen binding proteins and vectors and cells containing such nucleic acids are also provided. The antigen binding proteins have value in therapeutic methods in which it is useful to to stimulate GITR signaling, thereby inducing or enhancing an immune response in a subject. Accordingly, the antigen binding proteins have utility in a varienty of immunotherapy treatments, including treatment of various cancers and infections.
    Type: Application
    Filed: August 28, 2014
    Publication date: March 5, 2015
    Inventors: Courtney BEERS, Jason C. O'NEILL, Ian FOLTZ, Randal R. KETCHEM, Julia C. PIASECKI
  • HUMAN IL-23 ANTIGEN BINDING PROTEINS
    Publication number: 20140212428
    Abstract: Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
    Type: Application
    Filed: March 28, 2014
    Publication date: July 31, 2014
    Applicant: Amgen Inc.
    Inventors: Jennifer E. Towne, Janet D. Cheng, Jason C. O'Neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randal R. Ketchem
  • Human IL-23 antigen binding proteins
    Patent number: 8722033
    Abstract: Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
    Type: Grant
    Filed: October 26, 2010
    Date of Patent: May 13, 2014
    Assignee: Amgen Inc.
    Inventors: Jennifer E. Towne, Janet D. Cheng, Jason C. O'Neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randal R. Ketchem
  • HUMAN IL-23 ANTIGEN BINDING PROTEINS
    Publication number: 20130004501
    Abstract: Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
    Type: Application
    Filed: October 26, 2010
    Publication date: January 3, 2013
    Applicant: Amgen Inc.
    Inventors: Jennifer E. Towne, Janet D. Cheng, Jason C. O'Neill, Yu Zhang, Yu Sun, Heather Cerne, Derek E. Piper, Randal R. Ketchem