Abstract: An upper body positive pressure protection system protects the user from aerosolized contaminants and isolates a user's entire upper body from a contaminated environment. Filtered air is supplied to the suit by a reusable, rechargeable blower unit to ensure a non-contaminated and portable air supply for continuous positive pressure to the upper body suit. The blower unit is portable with the user and can be supported by a shoulder and waist belt harness. The reusable or disposable upper body suit can be constructed from a lightweight, splash/fluid resistant material that incorporates a clear face shield to allow appropriate visibility to the user. A reusable, adjustable head harness worn within a hood of the suit provides fixed positioning of the face shield relative to the user's face. Suit air exit vents may optionally include filters for capturing any biological contaminants the user may be expelling.