Patents by Inventor Jason Carte

Jason Carte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL CRISPR DNA AND RNA TARGETING ENZYMES AND SYSTEMS
    Publication number: 20230242891
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Application
    Filed: March 14, 2019
    Publication date: August 3, 2023
    Inventors: Elise Keston-Smith, David A. Scott, David R. Cheng, Winston X. Yan, Pratyusha Hunnewell, Jason Carte
  • NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS
    Publication number: 20220049273
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR-Cas systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Application
    Filed: February 28, 2020
    Publication date: February 17, 2022
    Inventors: David R. Cheng, David A. Scott, Winston X. Yan, Jason Carte, Elise Keston-Smith, Pratyusha Hunnewell, Shaorong Chong
  • STABILIZED REAGENTS FOR GENOME MODIFICATION
    Publication number: 20180327738
    Abstract: The present disclosure generally relates to compositions and methods for genetic modification of cells. In particular, the disclosure relates to stabilized reagents for genome alteration (e.g., site specific nucleases), as well as stabilized reagents for non-genetic code altering modification (e.g., DNA methylation). Stabilization methods include storage of reagents at suitable temperatures, conversion to dry forms, and chemical modifications.
    Type: Application
    Filed: November 18, 2016
    Publication date: November 15, 2018
    Inventors: Namritha RAVINDER, Robert Jason POTTER, Jason CARTE
  • Method for cleaving a target RNA using a Cas6 polypeptide
    Patent number: 9404098
    Abstract: Provided herein are methods for cleaving a target RNA polynucleotide. The target RNA polynucleotide includes a Cas6 recognition domain and a cleavage site, and may be based on a repeat from a CRISPR locus. The methods may be practiced in vivo or in vitro. Also provided are polypeptides that have Cas6 endoribonuclease activity in the presence of a target RNA polynucleotide, and methods for using the polypeptides.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: August 2, 2016
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Rebecca M. Terns, Michael P. Terns, Jason Carte
  • CAS6 POLYPEPTIDES AND METHODS OF USE
    Publication number: 20110217739
    Abstract: Provided herein are methods for cleaving a target RNA polynucleotide. The target RNA polynucleotide includes a Cas6 recognition domain and a cleavage site, and may be based on a repeat from a CRISPR locus. The methods may be practiced in vivo or in vitro. Also provided are polypeptides that have Cas6 endoribonuclease activity in the presence of a target RNA polynucleotide, and methods for using the polypeptides.
    Type: Application
    Filed: November 5, 2009
    Publication date: September 8, 2011
    Applicant: University of Georgia Research Foundation, Inc.
    Inventors: Rebecca M. Terns, Michael P. Terns, Jason Carte