Patents by Inventor Jason CHAKROFF
Jason CHAKROFF has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11806440Abstract: The instant disclosure is directed to methods of improving bone-soft tissue healing using biocompatible electrospun polymer fibers. In one embodiment, a method may include locating a portion of a subject's bone, affixing a tendon or ligament to the bone using a hardware fixture, and placing a patch comprising at least one electrospun polymer fiber in physical communication with both the bone and the tendon or ligament. In some embodiments, the bone may be a humerus, and the tendon or ligament may be a supraspinatus tendon. In certain embodiments, the patch may comprise substantially parallel electrospun polymer fibers, and may be placed such that the fibers are also substantially parallel with the long axis of the tendon or ligament.Type: GrantFiled: December 22, 2020Date of Patent: November 7, 2023Assignee: NFS IP Holdings, LLCInventors: Jed K. Johnson, Devan Ohst, Jason Chakroff, Brian Cohen, Anthony Romeo
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Publication number: 20230285445Abstract: A method of treating a chronic wound may comprise applying to the wound a first scaffold comprising an electrospun polymer fiber. The electrospun fiber may comprise a polymer selected from the group consisting of polyglycolic acid, poly(lactide-co-caprolactone), polylactic acid, polycaprolactone, copolymers thereof, and combinations thereof. The first scaffold may have a thickness from about 50 ?m to about 1 mm, a length from about 1 cm to about 20 cm, and a width from about 1 cm to about 15 cm. The method may further comprise keeping the first scaffold on the chronic wound for a time period of about 3 days to about 21 days. After the time period passes, the chronic wound may have a decreased planimetric area.Type: ApplicationFiled: January 10, 2023Publication date: September 14, 2023Applicant: NFS IP Holdings, LLCInventors: Jason CHAKROFF, Ronald Lloyd BRACKEN, Jed JOHNSON
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Patent number: 11576927Abstract: A method of treating a chronic wound may comprise applying to the wound a first scaffold comprising an electrospun polymer fiber. The electrospun fiber may comprise a polymer selected from the group consisting of polyglycolic acid, poly(lactide-co-caprolactone), polylactic acid, polycaprolactone, copolymers thereof, and combinations thereof. The first scaffold may have a thickness from about 50 ?m to about 1 mm, a length from about 1 cm to about 20 cm, and a width from about 1 cm to about 15 cm. The method may further comprise keeping the first scaffold on the chronic wound for a time period of about 3 days to about 21 days. After the time period passes, the chronic wound may have a decreased planimetric area.Type: GrantFiled: December 11, 2019Date of Patent: February 14, 2023Assignee: Nanofiber Solutions, LLCInventors: Jason Chakroff, Ronald Lloyd Bracken, Jed Johnson
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Publication number: 20210106720Abstract: The instant disclosure is directed to methods of improving bone-soft tissue healing using biocompatible electrospun polymer fibers. In one embodiment, a method may include locating a portion of a subject's bone, affixing a tendon or ligament to the bone using a hardware fixture, and placing a patch comprising at least one electrospun polymer fiber in physical communication with both the bone and the tendon or ligament. In some embodiments, the bone may be a humerus, and the tendon or ligament may be a supraspinatus tendon. In certain embodiments, the patch may comprise substantially parallel electrospun polymer fibers, and may be placed such that the fibers are also substantially parallel with the long axis of the tendon or ligament.Type: ApplicationFiled: December 22, 2020Publication date: April 15, 2021Applicant: NANOFIBER SOLUTIONS, LLCInventors: Jed K. JOHNSON, Devan OHST, Jason CHAKROFF, Brian COHEN, Anthony ROMEO
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Patent number: 10953097Abstract: A fiber may comprise an electrospun polymer and a contrast agent. A method of making an electrospun fiber may comprise configuring a receiving surface to receive a polymer fiber, applying a charge to one or more of the receiving surface, a polymer injection system, and a polymer solution ejected from the polymer injection system, and depositing a polymer solution ejected from the polymer injection system onto the receiving surface. The polymer solution may comprise a polymer and a contrast agent.Type: GrantFiled: November 2, 2016Date of Patent: March 23, 2021Assignee: NANOFIBER SOLUTIONS. LLCInventors: Jed Johnson, Devan Ohst, Jason Chakroff
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Patent number: 10898608Abstract: The instant disclosure is directed to methods of improving bone-soft tissue healing using biocompatible electrospun polymer fibers. In one embodiment, a method may include locating a portion of a subject's bone, affixing a tendon or ligament to the bone using a hardware fixture, and placing a patch comprising at least one electrospun polymer fiber in physical communication with both the bone and the tendon or ligament. In some embodiments, the bone may be a humerus, and the tendon or ligament may be a supraspinatus tendon. In certain embodiments, the patch may comprise substantially parallel electrospun polymer fibers, and may be placed such that the fibers are also substantially parallel with the long axis of the tendon or ligament.Type: GrantFiled: February 2, 2018Date of Patent: January 26, 2021Assignee: NANOFIBER SOLUTIONS, LLCInventors: Jed Johnson, Jason Chakroff, Devan Ohst, Brian Cohen, Anthony Romeo
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Publication number: 20200179437Abstract: A method of treating a chronic wound may comprise applying to the wound a first scaffold comprising an electrospun polymer fiber. The electrospun fiber may comprise a polymer selected from the group consisting of polyglycolic acid, poly(lactide-co-caprolactone), polylactic acid, polycaprolactone, copolymers thereof, and combinations thereof. The first scaffold may have a thickness from about 50 ?m to about 1 mm, a length from about 1 cm to about 20 cm, and a width from about 1 cm to about 15 cm. The method may further comprise keeping the first scaffold on the chronic wound for a time period of about 3 days to about 21 days. After the time period passes, the chronic wound may have a decreased planimetric area.Type: ApplicationFiled: December 11, 2019Publication date: June 11, 2020Applicant: Nanofiber Solutions, LLCInventors: Jason Chakroff, Ronald Lloyd Bracken, Jed Johnson
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Publication number: 20190388359Abstract: The instant disclosure is directed to methods of promoting the healing of concave wounds. A method for promoting the healing of a concave wound may comprise placing a scaffold over the concave wound, the scaffold comprising an electrospun polymer fiber. The scaffold may be pressed into the concave wound, such that the scaffold simultaneously contacts at least a bottom portion of the concave wound and at least a side portion of the concave wound. The method may be suture free. The scaffold employed in such a method may have an asterisk shape comprising a center and at least two spokes, and pressing the scaffold into the concave wound may comprise pressing the center of the scaffold into the bottom portion of the concave wound, and allowing the at least two spokes of the scaffold to fold upward to contact the side portion of the concave wound.Type: ApplicationFiled: June 26, 2019Publication date: December 26, 2019Inventors: Jed JOHNSON, Jason CHAKROFF
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Patent number: 10166315Abstract: A composition may comprise a plurality of polymeric electrospun fiber fragments, and a carrier medium comprising an effective amount of chitosan. Such a composition may further include a plurality of polymeric electrospun fiber fragment clusters. A kit may comprise a first component of a plurality of polymeric electrospun fiber fragments, and a second component of a carrier medium comprising an effective amount of chitosan. A method of treatment may comprise injecting into a portion of a body a composition which may comprise a plurality of polymeric electrospun fiber fragments, and a carrier medium comprising an effective amount of chitosan. The treatment may be directed to one or more of joint inflammation, osteoarthritis, a tissue injury, a muscle tear, a ligament tear, a tendon tear, a void, incontinence, an aneurysm, and a tumor.Type: GrantFiled: May 4, 2016Date of Patent: January 1, 2019Assignee: NANOFIBER SOLUTIONS, INC.Inventors: Jed Johnson, Ronald Lloyd Bracken, Jason Chakroff
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Publication number: 20180221537Abstract: The instant disclosure is directed to methods of improving bone-soft tissue healing using biocompatible electrospun polymer fibers. In one embodiment, a method may include locating a portion of a subject's bone, affixing a tendon or ligament to the bone using a hardware fixture, and placing a patch comprising at least one electrospun polymer fiber in physical communication with both the bone and the tendon or ligament. In some embodiments, the bone may be a humerus, and the tendon or ligament may be a supraspinatus tendon. In certain embodiments, the patch may comprise substantially parallel electrospun polymer fibers, and may be placed such that the fibers are also substantially parallel with the long axis of the tendon or ligament.Type: ApplicationFiled: February 2, 2018Publication date: August 9, 2018Inventors: Jed JOHNSON, Jason CHAKROFF, Devan OHST, Brian COHEN, Anthony ROMEO
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Publication number: 20170119886Abstract: A fiber may comprise an electrospun polymer and a contrast agent. A method of making an electrospun fiber may comprise configuring a receiving surface to receive a polymer fiber, applying a charge to one or more of the receiving surface, a polymer injection system, and a polymer solution ejected from the polymer injection system, and depositing a polymer solution ejected from the polymer injection system onto the receiving surface. The polymer solution may comprise a polymer and a contrast agent.Type: ApplicationFiled: November 2, 2016Publication date: May 4, 2017Inventors: Jed JOHNSON, Devan OHST, Jason CHAKROFF
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Publication number: 20160325015Abstract: A composition may comprise a plurality of polymeric electrospun fiber fragments, and a carrier medium comprising an effective amount of chitosan. Such a composition may further include a plurality of polymeric electrospun fiber fragment clusters. A kit may comprise a first component of a plurality of polymeric electrospun fiber fragments, and a second component of a carrier medium comprising an effective amount of chitosan. A method of treatment may comprise injecting into a portion of a body a composition which may comprise a plurality of polymeric electrospun fiber fragments, and a carrier medium comprising an effective amount of chitosan. The treatment may be directed to one or more of joint inflammation, osteoarthritis, a tissue injury, a muscle tear, a ligament tear, a tendon tear, a void, incontinence, an aneurysm, and a tumor.Type: ApplicationFiled: May 4, 2016Publication date: November 10, 2016Applicant: NANOFIBER SOLUTIONS, INC.Inventors: Jed JOHNSON, Ronald Lloyd BRACKEN, Jason CHAKROFF