Abstract: The present invention is a method to register 3D image data with fluoroscopic images of the chest of a patient. The ribs and spine, which are visible in the fluoroscopic images, are analyzed and a rib signature or cost map is generated. The rib signature or cost map is matched to corresponding structures of the 3D image data of the patient. Registration is evaluated by computing a difference between the fluoroscopic image and a virtual fluoroscopic projected image of the 3D data. Related systems are also described.

Abstract: A system and method are described for determining candidate fiducial marker locations in the vicinity of a lesion. Imaging information and data are input or received by the system and candidate marker locations are calculated and displayed to the physician. Additionally, interactive feedback may be provided to the physician for manually selected or identified sites. The physician may thus receive automatic real time feedback for a candidate fiducial marker location and adjust or accept a constellation of fiducial marker locations. 3D renderings of the airway tree, lesion, and marker constellations may be displayed.

Abstract: The present invention is a method to register 3D image data with fluoroscopic images of the chest of a patient. The ribs and spine, which are visible in the fluoroscopic images, are analyzed and a rib signature or cost map is generated. The rib signature or cost map is matched to corresponding structures of the 3D image data of the patient. Registration is evaluated by computing a difference between the fluoroscopic image and a virtual fluoroscopic projected image of the 3D data. Related systems are also described.

Abstract: The present invention is a method to register 3D image data with fluoroscopic images of the chest of a patient. The ribs and spine, which are visible in the fluoroscopic images, are analyzed and a rib signature or cost map is generated. The rib signature or cost map is matched to corresponding structures of the 3D image data of the patient. Registration is evaluated by computing a difference between the fluoroscopic image and a virtual fluoroscopic projected image of the 3D data. Related systems are also described.

Abstract: A medical analysis method for estimating a motion vector field of the magnitude and direction of local motion of lung tissue of a subject is described. In one embodiment a first 3D image data set of the lung and a second 3D image data set is obtained. The first and second 3D image data sets correspond to images obtained during inspiration and expiration respectively. A rigid registration is performed to align the 3D image data sets with one another. A deformable registration is perforated to match the 3D image data sets with one another. A motion vector field of the magnitude and direction of local motion of lung tissue is estimated based on the deforming step. The motion vector field may be computed prior to treatment to assist with planning a treatment as well as subsequent to a treatment to gauge efficacy of a treatment. Results may be displayed to highlight.

Abstract: The present invention is a method to register 3D image data with fluoroscopic images of the chest of a patient. The ribs and spine, which are visible in the fluoroscopic images, are analyzed and a rib signature or cost map is generated. The rib signature or cost map is matched to corresponding structures of the 3D image data of the patient. Registration is evaluated by computing a difference between the fluoroscopic image and a virtual fluoroscopic projected image of the 3D data. Related systems are also described.

Abstract: A method for assisting a physician track a surgical device in a body organ of a subject during a procedure includes fluoroscopic based registration, and tracking. An initial registration step includes receiving a 3D image data of a subject in a first body position, receiving a real time fluoroscopy image data, and estimating a deformation model or field to match points in the real time fluoro image with a corresponding point in the 3D model. A tracking step includes computing the 3D location of the surgical device based on a reference mark present on the surgical device, and displaying the surgical device and the 3D model of the body organ in a fused arrangement.

Abstract: A medical analysis method for estimating a motion vector field of the magnitude and direction of local motion of lung tissue of a subject is described. In one embodiment a first 3D image data set of the lung and a second 3D image data set is obtained. The first and second 3D image data sets correspond to images obtained during inspiration and expiration respectively. A rigid registration is performed to align the 3D image data sets with one another. A deformable registration is perforated to match the 3D image data sets with one another. A motion vector field of the magnitude and direction of local motion of lung tissue is estimated based on the deforming step. The motion vector field may be computed prior to treatment to assist with planning a treatment as well as subsequent to a treatment to gauge efficacy of a treatment. Results may be displayed to highlight.

Abstract: A medical analysis method for estimating a motion vector field of the magnitude and direction of local motion of lung tissue of a subject is described. In one embodiment a first 3D image data set of the lung and a second 3D image data set is obtained. The first and second 3D image data sets correspond to images obtained during inspiration and expiration respectively. A rigid registration is performed to align the 3D image data sets with one another. A deformable registration is performed to match the 3D image data sets with one another. A motion vector field of the magnitude and direction of local motion of lung tissue is estimated based on the deforming step. The motion vector field may be computed prior to treatment to assist with planning a treatment as well as subsequent to a treatment to gauge efficacy of a treatment. Results may be displayed to highlight.

Abstract: A method and system for use with an endoscopic instrument determines anatomical properties of body lumen at various states. Lumen properties such as lumen diameter are identified in two or more states corresponding to, for example, an inflated or deflated state. The lumen states are registered with one another and the anatomical properties are identified in real time at the location of an endoscope or endoscopic instrument used with the endoscope. In one embodiment a diametrical range of an airway is identified in real time at the location of a bronchoscope.

Abstract: A system and method are described for determining candidate fiducial marker locations in the vicinity of a lesion. Imaging information and data are input or received by the system and candidate marker locations are calculated and displayed to the physician. Additionally, interactive feedback may be provided to the physician for manually selected or identified sites. The physician may thus receive automatic real time feedback for a candidate fiducial marker location and adjust or accept a constellation of fiducial marker locations. 3D renderings of the airway tree, lesion, and marker constellations may be displayed.

Abstract: A system and method are described for determining candidate fiducial marker locations in the vicinity of a lesion. Imaging information and data are input or received by the system and candidate marker locations are calculated and displayed to the physician. Additionally, interactive feedback may be provided to the physician for manually selected or identified sites. The physician may thus receive automatic real time feedback for a candidate fiducial marker location and adjust or accept a constellation of fiducial marker locations. 3D renderings of the airway tree, lesion, and marker constellations may be displayed.

Abstract: A medical analysis method for estimating a motion vector field of the magnitude and direction of local motion of lung tissue of a subject is described. In one embodiment a first 3D image data set of the lung and a second 3D image data set is obtained. The first and second 3D image data sets correspond to images obtained during inspiration and expiration respectively. A rigid registration is performed to align the 3D image data sets with one another. A deformable registration is performed to match the 3D image data sets with one another. A motion vector field of the magnitude and direction of local motion of lung tissue is estimated based on the deforming step. The motion vector field may be computed prior to treatment to assist with planning a treatment as well as subsequent to a treatment to gauge efficacy of a treatment. Results may be displayed to highlight.

Abstract: A method and system for assisting a physician track a surgical device in a body organ of a subject during a procedure includes fluoroscopic based registration, tracking, and optimizing a fluoroscopy position. An initial registration step includes receiving a 3D image data of a subject in a first body position, receiving a real time fluoroscopy image data, and estimating a deformation model or field to match points in the real time fluoro image with a corresponding point in the 3D model. A tracking step includes computing the 3D location of the surgical device and displaying the surgical device and the 3D model of the body organ in a fused arrangement. Optimizing the fluoroscope camera pose includes computing a candidate camera pose to assist the surgeon to track a surgical device based on features of the surgical device, position of the patient, and mechanical properties or constraints of the fluoroscope.

Abstract: A system and method are described for determining candidate fiducial marker locations in the vicinity of a lesion. Imaging information and data are input or received by the system and candidate marker locations are calculated and displayed to the physician. Additionally, interactive feedback may be provided to the physician for manually selected or identified sites. The physician may thus receive automatic real time feedback for a candidate fiducial marker location and adjust or accept a constellation of fiducial marker locations. 3D renderings of the airway tree, lesion, and marker constellations may be displayed.

Abstract: A method and system for use with an endoscopic instrument determines anatomical properties of body lumen at various states. Lumen properties such as lumen diameter are identified in two or more states corresponding to, for example, an inflated or deflated state. The lumen states are registered with one another and the anatomical properties are identified in real time at the location of an endoscope or endoscopic instrument used with the endoscope. In one embodiment a diametrical range of an airway is identified in real time at the location of a bronchoscope.