Patents by Inventor Jason E. Fuller

Jason E. Fuller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10080876
    Abstract: Described here are devices, systems, and kits for delivering substances to tissues. The devices generally include one or more chambers (102) and a reservoir (108) within each chamber. The reservoir may locally deliver a microdose amount of a substance to a target tissue. In some variations, a microdose amount is used in early human studies, e.g., before a phase I clinical trial, to evaluate the effect of the substance on a target tissue, or to obtain pharmacokinetic or metabolic data. In other variations, a microdose amount is used to locally treat a medical condition. In yet other variations, a microdose amount is used to locally deliver a contrast agent for a structural or functional imaging procedure. Methods for delivering and retrieving the devices from the target tissue are also described.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: September 25, 2018
    Assignee: Kibur Medical, Inc.
    Inventors: Robert I. Tepper, Russell Hirsch, Jason E. Fuller, Jessica L. Duda, Craig Muir, Jeffrey S. Ross, J. Christopher Flaherty
  • Publication number: 20170252365
    Abstract: This invention is directed to ?-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The ?-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety.
    Type: Application
    Filed: July 26, 2016
    Publication date: September 7, 2017
    Inventors: Ifat RUBIN-BEJERANO, Gerald R. FINK, Claudia ABEIJON, Daniel S. KOHANE, Jason E. FULLER, Robert S. LANGER
  • Publication number: 20160331774
    Abstract: This invention is directed to ?-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The ?-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety.
    Type: Application
    Filed: July 26, 2016
    Publication date: November 17, 2016
    Inventors: Ifat Rubin-Bejerano, Gerald R. Fink, Claudia Abeijon, Daniel S. Kohane, Jason E. Fuller, Robert S. Langer
  • Patent number: 9457047
    Abstract: This invention is directed to ?-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The ?-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: October 4, 2016
    Assignees: Whitehead Institute, Massachusetts Institute of Technology, Trustees of Boston University, The General Hospital Corporation
    Inventors: Ifat Rubin-Bejerano, Gerald R. Fink, Claudia Abeijon, Daniel S. Kohane, Jason E Fuller, Robert S. Langer
  • Publication number: 20140030277
    Abstract: This invention is directed to ?-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The ?-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety.
    Type: Application
    Filed: September 26, 2013
    Publication date: January 30, 2014
    Applicants: Whitehead Institute, The General Hospital Corporation d/b/a Massachusetts General Hospital, Boston University, Massachusetts Institute of Technology
    Inventors: Ifat Rubin-Bejerano, Gerald R. Fink, Claudia Abeijon, Daniel S. Kohane, Jason E. Fuller, Robert S. Langer
  • Patent number: 8580253
    Abstract: This invention is directed to ?-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The ?-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety.
    Type: Grant
    Filed: November 6, 2007
    Date of Patent: November 12, 2013
    Assignees: Whitehead Institute, Massachusetts Institute of Technology, Trustees of Boston University, The General Hospital Corporation
    Inventors: Ifat Rubin-Bejerano, Gerald R. Fink, Claudia Abeijon, Danial S. Kohane, Jason E. Fuller, Robert S. Langer
  • Publication number: 20110230736
    Abstract: Described here are devices, systems, and kits for delivering substances to tissues. The devices generally include one or more chambers (102) and a reservoir (108) within each chamber. The reservoir may locally deliver a microdose amount of a substance to a target tissue. In some variations, a microdose amount is used in early human studies, e.g., before a phase I clinical trial, to evaluate the effect of the substance on a target tissue, or to obtain pharmacokinetic or metabolic data. In other variations, a microdose amount is used to locally treat a medical condition. In yet other variations, a microdose amount is used to locally deliver a contrast agent for a structural or functional imaging procedure. Methods for delivering and retrieving the devices from the target tissue are also described.
    Type: Application
    Filed: August 20, 2009
    Publication date: September 22, 2011
    Inventors: Robert I. Tepper, Russell Hirsch, Jason E. Fuller, Jessica L. Duda, Craig Muir, Jeffrey S. Ross, J. Christopher Flaherty
  • Publication number: 20110045049
    Abstract: This invention is directed to ?-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The ?-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety.
    Type: Application
    Filed: November 6, 2007
    Publication date: February 24, 2011
    Inventors: Ifat Rubin-Bejerano, Gerald R. Fink, Claudia Abeijon, Danial S. Kohane, Jason E. Fuller, Robert S. Langer