Patents by Inventor Jason Gordon Weatherhead

Jason Gordon Weatherhead has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemical Compounds
    Publication number: 20220144834
    Abstract: Compounds, specifically hepatitis B virus and/or hepatitis D virus inhibitors, more specifically compounds that inhibit HBe antigen and HBs antigen in a subject, for the treatment of viral infections, and methods of preparing and using such compounds.
    Type: Application
    Filed: October 25, 2021
    Publication date: May 12, 2022
    Inventors: John G. CATALANO, Pek Yoke CHONG, Hamilton D. DICKSON, Martin R. LEIVERS, Jason Gordon WEATHERHEAD
  • CHEMICAL COMPOUNDS
    Publication number: 20200255428
    Abstract: Compounds, specifically hepatitis B virus and/or hepatitis D virus inhibitors, more specifically compounds that inhibit HBe antigen and HBs antigen in a subject, for the treatment of viral infections, and methods of preparing and using such compounds.
    Type: Application
    Filed: October 5, 2018
    Publication date: August 13, 2020
    Applicant: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: John G. CATALANO, Pek Yoke CHONG, Hamilton D. DICKSON, Martin R. LEIVERS, Jason Gordon WEATHERHEAD
  • ISOINDOLINE DERIVATIVES
    Publication number: 20200255411
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: December 1, 2016
    Publication date: August 13, 2020
    Inventors: Brian Alvin JOHNS, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • ANTIBODY-DRUG CONJUGATES AND THERAPEUTIC METHODS USING THE SAME
    Publication number: 20190328900
    Abstract: The invention discloses an antibody-drug conjugate of Formula (I): Ab-[L-Dn]x??(I) wherein: Ab comprises a broadly neutralizing anti-HIV antibody; L comprises a linker molecule covalently bonded to said broadly neutralizing anti-HIV antibody; D comprises one or more drugs comprising an HIV therapeutic compound covalently bonded to said linker molecule L, wherein said one or more broadly neutralizing anti-HIV antibodies Ab specifically bind to an HIV envelope glycoprotein and said one or more drugs D specifically bind to an HIV envelope glycoprotein; n is selected from 1-4; and x is selected from 1-12.
    Type: Application
    Filed: June 30, 2017
    Publication date: October 31, 2019
    Inventors: Jerry JEFFREY, Jun TANG, Vincent Wing-Fai TAI, David TEMELKOFF, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • INDOLINE DERIVATIVES
    Publication number: 20190284136
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: July 17, 2017
    Publication date: September 19, 2019
    Inventors: Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • Benzoazepine derivatives
    Patent number: 10239840
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: March 26, 2019
    Assignee: VIIV HEALTHCARE UK LIMITED
    Inventors: Brian Alvin Johns, Lita S. Suwandi, Emile Johann Velthuisen, Jason Gordon Weatherhead
  • TETRAHYDROISOQUINOLINE DERIVATIVES
    Publication number: 20180334436
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: December 1, 2016
    Publication date: November 22, 2018
    Inventors: Brian Alvin JOHNS, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • ISOINDOLINE DERIVATIVES
    Publication number: 20180334453
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: December 1, 2016
    Publication date: November 22, 2018
    Inventors: Brian Alvin JOHNS, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • ISOINDOLINE DERIVATIVES
    Publication number: 20180327355
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: December 1, 2016
    Publication date: November 15, 2018
    Inventors: Brian Alvin JOHNS, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • Isoindolinone derivatives useful as antiviral agents
    Patent number: 10118894
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: November 6, 2018
    Assignee: ViiV HEALTHCARE UK LIMITED
    Inventors: Brian Alvin Johns, Emile Johann Velthuisen, Jason Gordon Weatherhead
  • Isoindoline derivatives for use in the treatment of a viral infection
    Patent number: 10112899
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: October 30, 2018
    Assignee: ViiV HEALTHCARE UK LIMITED
    Inventors: Brian Alvin Johns, Emile Johann Velthuisen, Jason Gordon Weatherhead, Lita Suwandi, David Temelkoff
  • ISOINDOLINE DERIVATIVES FOR USE IN THE TREATMENT OF A VIRAL INFECTION
    Publication number: 20180244617
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: July 6, 2015
    Publication date: August 30, 2018
    Inventors: Brian Alvin JOHNS, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD, Lita SUWANDI, David TEMELKOFF
  • BENZOAZEPINE DERIVATIVES
    Publication number: 20180179162
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: September 14, 2016
    Publication date: June 28, 2018
    Inventors: Brian Alvin JOHNS, Lita S. SUWANDI, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • ISOINDOLINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS
    Publication number: 20170204058
    Abstract: Compounds of Formula I are disclosed and methods of treating viral infections with compositions comprising such compounds.
    Type: Application
    Filed: July 20, 2015
    Publication date: July 20, 2017
    Inventors: Brian Alvin JOHNS, Emile Johann VELTHUISEN, Jason Gordon WEATHERHEAD
  • Substituted (3S,11AR)-N-[(2,4-difluorophenyl)methyl]-6-oxy-3-methyl-5,7-dioxo-2,3,5,7,11,11A-hexahydro[1,3]oxazolo[3,2-A]pyrido[1,2-D]pyrazine-8-carboxamides as HIV agents
    Patent number: 9707246
    Abstract: The invention is directed to a method for treatment of viral infections, particularly HIV infection. The method involves administering compounds which are substituted (3S,11aR)-N-[(2,4-difluorophenyl)methyl]-6-oxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamides of formula (I).
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: July 18, 2017
    Assignees: SHIONOGI & CO., LTD., VIIV HEALTHCARE COMPANY
    Inventors: Brian Alvin Johns, Jason Gordon Weatherhead, Toshikazu Hakogi, Yasunori Aoyama
  • CHEMICAL COMPOUNDS
    Publication number: 20150335667
    Abstract: The present invention features compounds that are prodrugs of HIV integrase inhibitors and therefore are useful in the delivery of compounds for the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC.
    Type: Application
    Filed: August 5, 2015
    Publication date: November 26, 2015
    Inventors: Brian Alvin JOHNS, Jason Gordon WEATHERHEAD, Toshikazu HAKOGI, Yasunori AOYAMA
  • Compounds and methods for treating HIV
    Patent number: 9163023
    Abstract: Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the retrovirus family of viruses such as the Human Immunodeficiency Virus (HIV).
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: October 20, 2015
    Assignee: ViiV Healthcare UK Limited
    Inventors: Martha Alicia De La Rosa, Brian Alvin Johns, Wieslaw Mieczyslaw Kazmierski, Vicente Samano, Lita Suwandi, David Temelkoff, Emile Velthuisen, Jason Gordon Weatherhead
  • (3S,11aR)-6-[(phenylmethyl)oxy]-3-methyl-2,3,11,11a-tetrahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-5,7-dione of the formula P-9 and/or (3S,11aR)-6-[(phenymethyl)oxy]-8-bromo-3-methyl-2,3,11,11a-tetrahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-5,7-dione of the formula P-10
    Patent number: 9133216
    Abstract: The compounds are intermediates in the preparation of therapeutic agents useful in the treatment of viral infections, particularly HIV infection. The compounds are (3S,11aR)-6-[(phenylmethyl)oxy]-3-methyl-2,3,11,11a-tetrahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-5,7-dione of the formula P-9 and/or (3S,11aR)-6-[(phenylmethyl)oxy]-8-bromo-3-methyl-2,3,11,11a-tetrahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-5,7-dione of the formula P-10.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: September 15, 2015
    Assignees: Shionogi & Co., Ltd., ViiV Healthcare Company
    Inventors: Brian Alvin Johns, Jason Gordon Weatherhead, Toshikazu Hakogi, Yasunori Aoyama
  • COMPOUNDS AND METHODS FOR TREATING HIV
    Publication number: 20150191469
    Abstract: Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the retrovirus family of viruses such as the Human Immunodeficiency Virus (HIV).
    Type: Application
    Filed: July 10, 2013
    Publication date: July 9, 2015
    Inventors: Martha Alicia De La Rosa, Brian Alvin Johns, Wieslaw Mieczyslaw Kazmierski, Vicente Samano, Lita Suwandi, David Temelkoff, Emile Velthuisen, Jason Gordon Weatherhead
  • (3S,11aR)-6-[(PHENYLMETHYL)OXY]-3-METHYL-2,3,11,11a-TETRAHYDROOXAZOLO[3,2-a]PYRIDO[1,2-d]PYRAZINE-5,7-DIONE OF THE FORMULA P-9 AND/OR (3S,11aR)-6-[(PHENYLMETHYL)OXY]-8-BROMO-3-METHYL-2,3,11,11a-TETRAHYDROOXAZOLO[3,2-a]PYRIDO[1,2-d]PYRAZINE-5,7-DIONE OF THE FORMULA P-10
    Publication number: 20150183803
    Abstract: The present invention features compounds that are prodrugs of HIV integrase inhibitors and therefore are useful in the delivery of compounds for the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC.
    Type: Application
    Filed: March 17, 2015
    Publication date: July 2, 2015
    Inventors: Brian Alvin JOHNS, Jason Gordon Weatherhead, Toshikazu Hakogi, Yasunori Aoyama