Abstract: A pharmacy claims switch is provided that allows pharmacy claims processors to determine the lowest cost for a prescription. A pharmacy submits a claim to the switch. The claim may be for a prescription for a patient and may identify a processor associated with the patient. The switch submits the claim to a third-party intermediary who submits the claim to the identified processor. The identified processor provides a response with a price for the patient. The third-party intermediary instructs the switch to submit follower claims to alternative processors. The switch receives responses from each alternative processor that includes a price the pharmacy should charge. Based on the prices in each response, the third-party intermediary selects the processor with the lowest price, and sends a response to the switch that identifies the selected processor. The pharmacy claims switch updates the pharmacy, which may present the best price to the patient.