Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.

Abstract: A playback device may be communicatively connected to a network device at a demonstration location. After connecting to the network device, the playback device may receive from the network device, a message indicating media content for playback by the playback device. In response to receiving the message, the playback device may play the media content, where playing the media content comprises modifying a default configuration of a demonstration mode. After receiving the message, the playback device may be disconnected from the network device. After disconnecting from the network device, the playback device may return to the default configuration of the demonstration mode.

Abstract: A playback device may be communicatively connected to a network device at a demonstration location. After connecting to the network device, the playback device may receive from the network device, a message indicating media content for playback by the playback device. In response to receiving the message, the playback device may play the media content, where playing the media content comprises modifying a default configuration of a demonstration mode. After receiving the message, the playback device may be disconnected from the network device. After disconnecting from the network device, the playback device may return to the default configuration of the demonstration mode.

Abstract: A playback device may be communicatively connected to a network device at a demonstration location. After connecting to the network device, the playback device may receive from the network device, a message indicating media content for playback by the playback device. In response to receiving the message, the playback device may play the media content, where playing the media content comprises modifying a default configuration of a demonstration mode. After receiving the message, the playback device may be disconnected from the network device. After disconnecting from the network device, the playback device may return to the default configuration of the demonstration mode.

Abstract: A playback device may be communicatively connected to a network device at a demonstration location. After connecting to the network device, the playback device may receive from the network device, a message indicating media content for playback by the playback device. In response to receiving the message, the playback device may play the media content, where playing the media content comprises modifying a default configuration of a demonstration mode. After receiving the message, the playback device may be disconnected from the network device. After disconnecting from the network device, the playback device may return to the default configuration of the demonstration mode.

Abstract: A playback device may be communicatively connected to a network device at a demonstration location. After connecting to the network device, the playback device may receive from the network device, a message indicating media content for playback by the playback device. In response to receiving the message, the playback device may play the media content, where playing the media content comprises modifying a default configuration of a demonstration mode. After receiving the message, the playback device may be disconnected from the network device. After disconnecting from the network device, the playback device may return to the default configuration of the demonstration mode.

Abstract: A playback device may be communicatively connected to a network device at a demonstration location. After connecting to the network device, the playback device may receive from the network device, a message indicating media content for playback by the playback device. In response to receiving the message, the playback device may play the media content, where playing the media content comprises modifying a default configuration of a demonstration mode. After receiving the message, the playback device may be disconnected from the network device. After disconnecting from the network device, the playback device may return to the default configuration of the demonstration mode.

Abstract: A playback device may be communicatively connected to a network device at a demonstration location. After connecting to the network device, the playback device may receive from the network device, a message indicating media content for playback by the playback device. In response to receiving the message, the playback device may play the media content, where playing the media content comprises modifying a default configuration of a demonstration mode. After receiving the message, the playback device may be disconnected from the network device. After disconnecting from the network device, the playback device may return to the default configuration of the demonstration mode.

Abstract: Systems, methods, apparatus, and articles of manufacture to demonstrate playback device operation at a point of sale location are disclosed. An example system includes a playback device configured for demonstration playback by one or more users at the point of sale location. The example playback device is to respond to an allowed set of user commands to provide content playback. The example system includes a user control to facilitate user interaction with the playback device and to provide information for user review regarding the playback device. The example user control includes an option for user selection to provide additional information regarding playback device functionality. The example user control is restricted to provide repeatable playability of the playback device for demonstration at the point of sale location. The example system is to monitor the playback device for repeatable playability by users in the system.

Abstract: A scene illumination system is provided that produces spatially uniform or controlled brightness levels for machine vision applications. The system includes a camera, multiple light sources that preferentially illuminate different regions within the camera's field-of-view, and a processing unit coupled to the camera and light sources. Focal regions of the light sources within the camera's field-of-view are sampled to determine average regional brightness and compared to target brightness levels. The processing unit controls the light sources to increase or decrease illumination levels to converge toward the target brightness levels within the field-of-view. This modulation of the light sources may be repeated with successive video images until target brightness levels are achieved.

Abstract: A scene illumination system is provided that produces spatially uniform or controlled brightness levels for machine vision applications. The system includes a camera, multiple light sources that preferentially illuminate different regions within the camera's field-of-view, and a processing unit coupled to the camera and light sources. Focal regions of the light sources within the camera's field-of-view are sampled to determine average regional brightness and compared to target brightness levels. The processing unit controls the light sources to increase or decrease illumination levels to converge toward the target brightness levels within the field-of-view. This modulation of the light sources may be repeated with successive video images until target brightness levels are achieved.

Abstract: Systems, methods, apparatus, and articles of manufacture to demonstrate playback device operation at a point of sale location are disclosed. An example system includes a playback device configured for demonstration playback by one or more users at the point of sale location. The example playback device is to respond to an allowed set of user commands to provide content playback. The example system includes a user control to facilitate user interaction with the playback device and to provide information for user review regarding the playback device. The example user control includes an option for user selection to provide additional information regarding playback device functionality. The example user control is restricted to provide repeatable playability of the playback device for demonstration at the point of sale location. The example system is to monitor the playback device for repeatable playability by users in the system.

Abstract: A scene illumination system is provided that produces spatially uniform or controlled brightness levels for machine vision applications. The system includes a camera, multiple light sources that preferentially illuminate different regions within the camera's field-of-view, and a processing unit coupled to the camera and light sources. Focal regions of the light sources within the camera's field-of-view are sampled to determine average regional brightness and compared to target brightness levels. The processing unit controls the light/sources to increase or decrease illumination levels to converge toward the target brightness levels within the field-of-view. This modulation of the light sources may be repeated with successive video images until target brightness levels are achieved.