Abstract: Described herein are heteroaryl compounds with estrogen receptor modulation activity or function having the Formula I, II, and III structures: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I, II, and III compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Abstract: Methods and systems for plug-and-abandon applications are included. A method comprises providing an extended-life cement composition comprising calcium aluminate cement, water, and a cement set retarder. The method further comprises mixing the extended-life cement composition with a cement set activator to activate the extended-life cement composition, introducing the activated extended-life cement composition into a wellbore, and allowing the activated extended-life cement composition to set in the wellbore to form a plug in the wellbore. The plug has a permeability of less than 0.1 millidarcy.

Abstract: Aspects of the present disclosure provide methods and apparatuses for processing a digital image of a document, for example, to determine whether the document is a long document. An exemplary method generally includes obtaining a plurality of digital images of the document, segmenting at least a first digital image of the plurality of images into pixels associated with a foreground of the first digital image and pixels associated with a background of the first digital image, detecting a plurality of contours in the segmented first digital image, deciding, for each detected contour of the plurality of contours, whether that contour is an open contour or a closed contour, and determining that one or more sides of the document is out-of-bounds based, at least in part, on the decisions.

Abstract: A system for conducting the identification and quantification of micro-organisms, e.g., bacteria in urine samples which includes: 1) several disposable cartridges for holding four disposable components including a centrifuge tube, a pipette tip having a 1 ml volume, a second pipette tip having a 0.5 ml volume, and an optical cup or cuvette; 2) a sample processor for receiving the disposable cartridges and processing the urine samples including transferring the processed urine sample to the optical cups; and 3) an optical analyzer for receiving the disposable cartridges and configured to analyze the type and quantity of micro-organisms in the urine sample. The disposable cartridges with their components including the optical cups or cuvettes are used in the sample processor, and the optical cups or cuvettes containing the processed urine samples are used in the optical analyzer for identifying and quantifying the type of micro-organism existing in the processed urine samples.

Abstract: Examples associated with display mapping are described. One example system includes a display mapping module. The display mapping module maps display components connected to the system to virtual channels to which the system is subscribed. A communication module transmits a content instruction to subscribers of a virtual channel. The instruction controls the subscribers of the virtual channel to display content associated with the content instruction on display components the respective subscribers have mapped to the virtual channel. A display module causes a display component mapped to the virtual channel to display content associated with the content instruction.

Abstract: In one embodiment, a method includes accessing input data from one or more different input sources. The input sources include: one or more cameras, one or more microphones, and a social graph maintained by a social-networking system. Based on the input data, generating a current descriptive model for a current audio-video communication session that comprises one or more descriptive characteristics about (1) an environment associated with the current audio-video communication session, (2) one or more people within the environment, or (3) one or more contextual elements associated with the current audio-video communication session. The method also includes generating one or more instructions for the current audio-video communication session that are based the one or more descriptive characteristics; and sending the one or more instructions to a computing device associated with the one or more cameras and the one or more microphones.

Abstract: A pressure washer includes a prime mover, a water pump, the water pump including a pump inlet for receiving fluid from a fluid source and a pump outlet for supplying a pressurized primary fluid, a jet pump including a primary fluid inlet fluidly coupled to the pump outlet, a secondary fluid inlet, and a fluid outlet, and a spray gun configured to be fluidly coupled to the fluid outlet of the jet pump, the spray gun including a spray gun outlet having a variable effective flow area. Wherein, in operation, in a high pressure operating mode, the pressurized primary fluid flows through the jet pump and exits through the fluid outlet of the jet pump, and in a high flow operating mode, the pressurized primary fluid flows through the jet pump and entrains a secondary fluid supplied through the secondary fluid inlet, resulting in a combined fluid flow.

Abstract: A method may include receiving image data representative of cash acquired via one or more image sensors, identifying a first currency depicted in the cash based on a plurality of images associated with a plurality of currencies, and determining a currency conversion rate between the first currency and a second currency. The method may also include generating a visualization representative of a currency value of the cash in the second currency based on the currency conversion rate and overlaying the visualization on the image data.

Abstract: A method includes a first computing device encrypting a portion of a data matrix based on a set of encryption keys to produce an encrypted data matrix. The method further includes the first computing device sending the encrypted data matrix to a second computing device. The method further includes the second computing device dispersed storage error encoding the data matrix to produce a set of encrypted encoded data slices. The method further includes the second computing device sending the set of encrypted encoded data slices to a set of storage units of the DSN for storage therein.

Abstract: A modular power conversion system and power electronics enabling any power production device or entity to connect to any load or electrical grid including, but not limited to, electricity conversion between low level producer(s) such as a diesel or gas generator, Stirling engine, wind turbine or photovoltaic array, to a consumer such as a commercial or residential building, either directly or via the grid, is disclosed. The modular power conversion system including hardware and software power electronics designed as a modular power stage aggregating different power production entities, transmission systems, consumption and loads as well as energy storage is also disclosed.

Abstract: The present invention provides an inbred corn line designated KFX5302, methods for producing a corn plant by crossing plants of the inbred line KFX5302 with plants of another corn plant. The invention further encompasses all parts of inbred corn line KFX5302, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line KFX5302, and plants produced according to these methods.

Abstract: Systems and methods are provided for use in asynchronous processing of events within a network. One exemplary method includes receiving multiple events for asynchronous processing, each defined by at least one rule, and assigning, by a computing device, the multiple events to an event queue. The method also includes retrieving, by the computing device, a first one of the multiple events from the event queue; transforming, by the computing device, the first one of the multiple events into a first event object; and recording, by the computing device, the first event object to a data structure. The method further includes identifying, by the computing device, at least one notification message associated with the first event object and causing, by the computing device, the at least one notification message, associated with the first event object, to be delivered.

Abstract: Recombinant paramyxoviruses including a viral genome encoding a heterologous gene are provided. In several embodiments, the recombinant paramyxovirus is a recombinant parainfluenza virus, such as a recombinant PIV3 including a viral genome encoding a heterologous respiratory syncytial virus F ectodomain linked to the transmembrane domain and the cytoplasmic tail of the F protein from the PIV3. Nucleic acid molecules including the genome of a recombinant paramyxoviruses are also provided. The recombinant viruses may advantageously be used in vaccine formulations, such as for vaccines against parainfluenza virus and respiratory syncytial virus.

Abstract: A system includes an augmented virtual reality (AVR) object creation engine, an AVR object enhancement engine, an AVR object positioning engine, and an AVR media authoring engine. The AVR object creation engine is configured to convert real world data into one or more AVR objects. The AVR object enhancement engine is configured to enhance the one or more AVR objects to include at least one of processed data visualization and multiuser controls. The AVR object positioning engine is configured to position the enhanced one or more AVR objects in a virtual space-time. The AVR media authoring engine is configured to make available, as AVR media, a scene tree including the virtual space-time in which the enhanced one or more AVR objects are positioned.

Abstract: A system includes a circuit interrupter including a light source structured to output light and a first processor structured to obtain information associated with the circuit interrupter and to control the light source to output light in a pattern representing the information. The system also include an adapter structured to detect light output by the light source, convert the detected light to another form, and to output the converted form of the light and an electronic device structured to receive the converted form of the light. The electronic device includes a second processor structured to convert the converted form of the light into the information.

Abstract: In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.

Abstract: Disclosed embodiments include vacuum electronics devices and methods of fabricating a vacuum electronics device. In a non-limiting embodiment, a vacuum electronics device includes: an electrode; a plurality of grid supports disposed on the electrode, each of the plurality of grid supports having a first width; and a plurality of grid lines, each of the plurality of grid lines being supported on an associated one of the plurality of grid supports, each of the plurality of grid lines having a second width that is wider than the first width.

Abstract: A container includes a cup formed to include and interior region and an insulated sleeve. The insulated sleeve is coupled to an outer surface of the cup.

Abstract: Disclosed are compounds of formula (I), pharmaceutical compositions comprising such compounds and methods/uses of using the same, for example, for treating a JAK-related disorder, such as cancer, cancer cachexia or an immune disorder: wherein R1 is methyl or ethyl; R2 is selected from methyl, ethyl, methoxy and ethoxy; R3 is selected from hydrogen, chlorine, fluorine, bromine and methyl; R4 is selected from methyl, ethyl and —CH2OCH3; R5 and R6 are each individually methyl or hydrogen; and R7 is selected from methyl, ethyl, —(CH2)2OH and —(CH2)2OCH3, or a pharmaceutically acceptable salt thereof.