Abstract: Some embodiments of the present disclosure relate to a composite membrane. In some embodiments, the composite membrane comprises a first fluoropolymer membrane and a second fluoropolymer membrane. In some embodiments a difference between a second surface energy of the second fluoropolymer membrane and a first surface energy of the first fluoropolymer membrane is at least 10 mN/m at 20° C. In some embodiments, the composite membrane has a Z strength of at least 5 psi.

Abstract: The invention is an improved biocompatible surface for a variety of medical purposes. The biocompatible surface employs a unique tight microstructure that demonstrates enhanced cellular response in the body, particularly when placed in contact with blood. As a blood contact surface, the present invention can be beneficially employed in a wide variety of implantable devices and in many other devices and equipment that come in contact with blood.

Abstract: The invention is an improved biocompatible surface for a variety of medical purposes. The biocompatible surface employs a unique tight microstructure that demonstrates enhanced cellular response in the body, particularly when placed in contact with blood. As a blood contact surface, the present invention can be beneficially employed in a wide variety of implantable devices and in many other devices and equipment that come in contact with blood.

Abstract: A sterilizing grade filter including at least two non-sterile nanofiber membranes positioned in a stacked configuration is provided. The nanofiber membranes have a bubble point from about 10 psi to about 50 psi, a thickness less than about 300 microns, and a mass/area less than about 20 g/m2. The non-sterile nanofiber membranes are separated from each other by a distance d, which may be less than about 100 microns. The membranes may be adhered together produce a composite stacked filtration material. Methods of producing a sterilizing grade filter are also provided.

Abstract: A mycoplasma retentive filter having an LRV greater than 8 including at least two mycoplasma non-retentive fluoropolymer membranes positioned in a stacked configuration is provided. The fluoropolymer membranes a bubble point from about 30 psi to about 90 psi, a thickness less than about 10 microns, and a mass/area less than about 10 g/m2. The mycoplasma non-retentive fluoropolymer membranes are is separated from each other by a distance d, which may be less than about 100 microns. The fluoropolymer membranes may be laminated or co-expanded to produce a composite stacked filtration material. In exemplary embodiments, at least one of the fluoropolymer membranes is an expanded polytetrafluoroethylene membrane. In one embodiment, the surface morphology of the fluoropolymer membranes are substantially the same and contain no or substantially no free fibrils. Methods of producing a sterilizing grade filter are also provided.

Abstract: A sterilizing grade filter including at least two non-sterile fluoropolymer membranes positioned in a stacked configuration is provided. The fluoropolymer membranes a bubble point from about 10 psi to about 50 psi, a thickness less than about 10 microns, and a mass/area less than about 10 g/m2. The non-sterile fluoropolymer membranes are is separated from each other by a distance d, which may be less than about 100 microns. The fluoropolymer membranes may be laminated or co-expanded to produce a composite stacked filtration material. In exemplary embodiments, at least one of the fluoropolymer membranes is an expanded polytetrafluoroethylene membrane. In one embodiment, the surface morphology of the fluoropolymer membranes are substantially the same and contain no or substantially no free fibrils. Methods of producing a sterilizing grade filter are also provided.

Abstract: The invention is an improved biocompatible surface for a variety of medical purposes. The biocompatible surface employs a unique tight microstructure that demonstrates enhanced cellular response in the body, particularly when placed in contact with blood. As a blood contact surface, the present invention can be beneficially employed in a wide variety of implantable devices and in many other devices and equipment that come in contact with blood.

Abstract: Novel porous PTFE membranes are described possessing a unique combination of high strength, low flow resistance, and small pore size. Additionally, unique constructions with superior filtration and venting properties incorporating porous PTFE membranes are described.

Abstract: The invention is an improved biocompatible surface for a variety of medical purposes. The biocompatible surface employs a unique tight microstructure that demonstrates enhanced cellular response in the body, particularly when placed in contact with blood. As a blood contact surface, the present invention can be beneficially employed in a wide variety of implantable devices and in many other devices and equipment that come in contact with blood.

Abstract: Novel porous PTFE membranes are described possessing a unique combination of high strength, low flow resistance, and small pore size. Additionally, unique constructions with superior filtration and venting properties incorporating porous PTFE membranes are described.

Abstract: Novel porous PTFE membranes are described possessing a unique combination of high strength, low flow resistance, and small pore size. Additionally, unique constructions with superior filtration and venting properties incorporating porous PTFE membranes are described.