Abstract: Methods and systems for managing a configuration of a client deployment to provide a service are disclosed. The configuration may be managed by managing configuration drift that may occur in the configuration of the client deployment. The configuration drift may be managed by monitoring for changes in the configuration and restoring the configuration to a goal configuration. The changes may be monitored by constructing knowledge graphs using the configurations. A knowledge graph of a current configuration may be compared to a knowledge graph of a goal configuration to find a difference. The difference may represent a configuration drift. The configuration drift in the current configuration may be remedied to restore the current configuration to the goal configuration.

Abstract: The present application discloses a climbing robot (10) for climbing ferrous structures (30), a dual gear pivot mechanism for a climbing robot (10), and a method of controlling a climbing robot (10) for climbing ferrous structures (30). The climbing robot (10) comprises three drive units (12, 14, 16) coupled together and the central drive unit is coupled to a pivot mechanism (24). Each drive unit (12, 14, 16) comprises a wheel arrangement (13, 15, 17) comprising at least one wheel configured to adhere to a ferrous tower (30), and each wheel is independently controllable. A first wheel arrangement (13) is the wheel arrangement of one of the three drive units (12, 14, 16). A second wheel arrangement (15) is the wheel arrangement of another one of the three drive units (12, 14, 16).

Abstract: Methods, systems, and computer programs are presented for the management of lane-departure (LD) events. One method includes training a classifier for LD events and loading the classifier into a vehicle. LD events are detected based on outward images using the classifier, while the turn signal is monitored to prevent false triggers. If an LD event is detected, rules are checked for alerting the driver and deciding whether to alert the driver or not. Subsequently, additional rules are checked for reporting the event and deciding whether to report the event to a Behavior Monitoring System (BMS) or to discard it. The method also includes a solid line departure model that identifies crossing dashed, solid-white, and solid-yellow lanes, delaying alerts and event generation until a significant portion of the vehicle crosses over the lane. The model also outputs a confidence score reflecting the amount of vehicle deviation from the driving lane.

Abstract: A computing platform configurable to allow users to graphically represent relationships between database records may be provided to a plurality of organizations. A request to generate a customizable visualization for graphically representing relationships between a root database record and child database records in a customizable format may be processed. Graphical representations of the root database record and the child database records may be caused to be displayed in accordance with the customizable format.

Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.

Abstract: The present disclosure provides systems and methods for transposing a cargo nucleotide sequence to a target nucleic acid site. These systems and methods may comprise a first double-stranded nucleic acid comprising the cargo nucleotide sequence, wherein the cargo nucleotide sequence is configured to interact with a recombinase or transposase complex, a cas effector complex comprising a cas effector and at least one engineered guide polynucleotide configured to hybridize to the target nucleic acid site, and the recombinase or transposase complex wherein said recombinase or transposase complex is configured to recruit the cargo nucleotide to the target nucleic acid site.

Abstract: A microarray chip imaging detector comprises a housing configured to receive a microarray chip. The detector includes a laser assembly supported by the housing and oriented at an angle relative to the microarray chip, the laser assembly configured to transmit an excitation beam along a first axis to samples on the microarray chip. The detector also includes a camera supported by the housing and positioned along a second axis, the camera configured to receive fluorescent light emitted from fluorophores in the samples on the microarray chip, the second axis oriented at an angle less than 30 degrees relative to the first axis. The housing includes a plurality of baffles positioned between the microarray chip and the camera, and a plurality of laser beamstops to receive the excitation beam reflected off the microarray chip.

Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.

Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.

Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.

Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.

Abstract: The present disclosure provides systems and methods for transposing a cargo nucleotide sequence to a target nucleic acid site. These systems and methods may comprise a first double-stranded nucleic acid comprising the cargo nucleotide sequence, wherein the cargo nucleotide sequence is configured to interact with a recombinase complex, a cas effector complex comprising a cas effector and at least one engineered guide polynucleotide configured to hybridize to the target nucleic acid site, and the recombinase complex wherein said recombinase complex is configured to recruit the cargo nucleotide to the target nucleic acid site.

Abstract: Described herein is an assay device, comprising a substrate comprising microfluidic geometry, and a reagent layer disposed adjacent to the substrate.

Abstract: A system, a control unit, and a method for deciding a geofence event of a vehicle is disclosed.

Abstract: A pipe (12) coupling assembly (16, 116) includes a body (64, 120), a rib (65, 122), and teeth (56, 124). The body (64, 118) has an outer diameter and first and second inner diameter sections (68, 128, 70, 130). The first inner diameter section (68, 128) is wider than the second inner diameter section (70, 130). The rib (65, 122) extends around the first diameter section (68, 128) and projects radially inwardly therefrom. The teeth (56, 124) are situated within the second inner diameter section (70, 130) and project radially inwardly toward a central axis (38, 134) of the body (64, 120).

Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.

Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.

Abstract: A microarray chip imaging detector comprises a housing configured to receive a microarray chip. The detector includes a laser assembly supported by the housing and oriented at an angle relative to the microarray chip, the laser assembly configured to transmit an excitation beam along a first axis to samples on the microarray chip. The detector also includes a camera supported by the housing and positioned along a second axis, the camera configured to receive fluorescent light emitted from fluorophores in the samples on the microarray chip, the second axis oriented at an angle less than 30 degrees relative to the first axis. The housing includes a plurality of baffles positioned between the microarray chip and the camera, and a plurality of laser beamstops to receive the excitation beam reflected off the microarray chip.

Abstract: Disclosed herein are genetically modified microorganisms and related methods for the enhanced export of oligosaccharides. The microorganisms described herein express major facility superfamily proteins such as CDT-1 which allows for the export of oligosaccharides. Variants of CDT-1 exhibit higher activity regarding oligosaccharide export. Means to export oligosaccharides into the growth medium are provided herein.