Abstract: A delivery device may be configured to deliver an agent to a target tissue through a channel of a medical device, the delivery device may include a body including (a) a coupling region configured to removably attach to a handle of the medical device, and (b) a coupler including an exit port for aligning with a port of the channel, wherein the coupler is configured to mate with the port of the channel; a source of an agent; and a source of pressurized fluid. The body, the source of agent, and the source of pressurized fluid may be arranged to deliver agent and pressurized fluid to the exit port for delivery through the channel.

Abstract: A use of empagliflozin for the treatment of ulcerative colitis and Crohn's disease.

Abstract: Methods and systems are provided for generation of lower-frequency tactile energy (e.g., vibration) of a vehicle system based on audio signals. In one example, a method may include acquiring an audio signal from an audio system, generating a motor input command, and applying the motor input command to at least a first traction motor and a second traction motor to create a resultant vibrational force.

Abstract: Content is organized for brands by selecting a plurality of brand templates. After each selection, a set of properties is generated by applying a portion of settings of the respective brand template, with the remaining settings being overridden with settings for a channel communicating one of a plurality of presentations to a node of a network involved in the communication. The plurality of presentations may include different renditions of the same content. The properties may include sections configured for different focus areas and/or types of content associated with at tags to enable brand-level-targeting. Filters may be identified in the properties. Based on each of the identifications, a property from among the generated sets of properties may be selected based on comparisons with the associated tags.

Abstract: A delivery device may be configured to deliver an agent to a target tissue through a channel of a medical device, the delivery device may include a body including (a) a coupling region configured to removably attach to a handle of the medical device, and (b) a coupler including an exit port for aligning with a port of the channel, wherein the coupler is configured to mate with the port of the channel; a source of an agent; and a source of pressurized fluid. The body, the source of agent, and the source of pressurized fluid may be arranged to deliver agent and pressurized fluid to the exit port for delivery through the channel.

Abstract: The invention relates generally to antibodies, activatable antibodies, multispecific antibodies, and multispecific activatable antibodies that specifically bind to at least CD3, as well as to methods of making and using these antibodies, activatable antibodies, multispecific antibodies, and/or multispecific activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: Circuits, systems and methods are provided. A circuit includes a subsystem, an interface, and a debugger. The interface includes power processing and management (PPM) circuitry coupled to the subsystem, and arbitration logic coupled to the PPM circuitry. In operation, the debugger issues a debug request to the arbitration logic to perform a debug operation on the subsystem, and, in response to the debug request, the arbitration logic provides an interrupt associated with the subsystem to the PPM circuitry. The PPM circuitry, in response to the interrupt and a determination that the subsystem is OFF, powers on the subsystem and provides a notification to the arbitration logic indicating that the subsystem is ON. The PPM circuitry also receives a notification from the arbitration logic that the debug operation related to the debug request is complete, and powers off the subsystem in response to that notification.

Abstract: Embodiments include a device having a processor core that can operate in any of multiple operating modes, and a controller that issues a debug request to the processor core. The processor core includes a register configured to store current operating state information of the processor core. The debug request includes a first portion to specify a virtual machine qualifier with respect to servicing the debug request, a second portion to specify a processor core operating mode qualifier with respect to servicing the debug request, and a third portion to specify a function qualifier with respect to servicing the debug request. Each qualifier can be enabled to make the qualifier a condition of servicing the debug request. When all enabled qualifiers are satisfied, the processor core services the debug request. The servicing of the debug request may be performed in real-time without suspending the processing device.

Abstract: An integrated circuit includes: a debugger; and an interface coupled to the debugger. The interface has: arbitration logic coupled to the debugger; a power processor coupled to the arbitration logic; and a power management network coupled to the power processor. The integrated circuit also includes subsystems coupled to the interface. The debugger is configured to perform debugging operations of the subsystems via the interface.

Abstract: Devices and methods are provided for identifying a debug event associated with a data element of a data stream, and performing debugging when a processor executes a software program in connection with the data stream. The debug event is tracked through a data pipeline to the processor. In an embodiment, the debug event is acted on only when the processor is ready to consume the data element associated with the debug event. In an embodiment, the debug event is determined by monitoring iteration counts of loop counters associated with an address generator and comparing the iteration counts to respective stored count values.

Abstract: Disclosed embodiments include a processing device having a debug controller that issues a context-sensitive debug request. The context-sensitive debug request includes at least one conditional criteria. A processing core receives the debug request, determines whether all of the at least one conditional criteria are true, and services the debug request when all of the at least one conditional criteria are true by accessing a data location indicated in the debug request. The servicing of the debug request may be performed in real-time mode without suspending the processing device, and the accessing can be a read or a write operation depending on the type of access indicated in the debug request. The conditional criteria may include one or more of a processor mode condition, a virtual machine identifier condition, and a debug context condition.

Abstract: A method for debugging a software program is provided when the software program is executed on a processor. An asynchronous debug event is detected. The asynchronous debug event is tracked through a data pipeline to the processor. In one embodiment, the asynchronous debug event is acted on only when the processor is ready to consume a data element associated with the asynchronous debug event.

Abstract: A system and method are presented to improve the speed of shared network processing by filtering data using a filter list. The filter list filters the data submitted for analysis to the server system. Some data is processed locally, but the filtered data is processed at the server system. The local systems process similar data, but they use distinct data hierarchies to classify the data. Hierarchy designations are utilized in the filter list to filter the data. Rules establish a unified hierarchy that is translated to local hierarchies in the filter lists. Tags are established at the server for exceptions. Tags are translated into data identifiers for inclusion in the filter lists. The size of the filter list is reduced by avoiding redundancies between the tagged data identifiers and the local hierarchy designations. The filter list creation process also creates pre-analysis data at the server to assist in its analysis.

Abstract: A system and method is presented for product substantiation and promotion redemption. A purchased product list is transmitted from a retail store system to a promotion analysis server along with a user identifier. The promotion analysis server identifies promotions available to the user, and then considers whether the benefits under the promotions are still available to the user. Discounts for available promotions related to the purchased product list are calculated and transmitted to the retail store system for deduction from the transactions. An approved product list can be provided that filters the purchased product list before transmittal. The approved product list can include promotions from a plurality of programs.

Abstract: Disclosed embodiments include a processing device having a debug controller that issues a context-sensitive debug request. The context-sensitive debug request includes at least one conditional criteria. A processing core receives the debug request, determines whether all of the at least one conditional criteria are true, and services the debug request when all of the at least one conditional criteria are true by accessing a data location indicated in the debug request. The servicing of the debug request may be performed in real-time mode without suspending the processing device, and the accessing can be a read or a write operation depending on the type of access indicated in the debug request. The conditional criteria may include one or more of a processor mode condition, a virtual machine identifier condition, and a debug context condition.

Abstract: A system and method is presented for product substantiation and promotion redemption. A purchased product list is transmitted from a retail store system to a promotion analysis server along with a user identifier. The promotion analysis server identifies promotions available to the user, and then considers whether the benefits under the promotions are still available to the user. Discounts for available promotions related to the purchased product list are calculated and transmitted to the retail store system for deduction from the transactions. An approved product list can be provided that filters the purchased product list before transmittal. The approved product list can include promotions from a plurality of programs.

Abstract: A real-time debugger implementation maintains and manages multiple debug contexts allowing developers to interact with real-time applications without “breaking” the system in which the debug application is executing. The debugger allows multiple debug contexts to exist and allows break points in real-time and non-real-time code portions of one or more applications executing on a debug enabled core of a processor. A debug monitor function may be implemented as a hardware logic module on the same integrated circuit as the processor. Higher priority interrupt service requests may be serviced while otherwise maintaining a context for the debug session (e.g., stopped at a developer defined breakpoint). Accordingly, the application developer executing the debugger may not have to be concerned with processing occurring on the processor that may be unrelated to the current debug session.

Abstract: Disclosed embodiments include a processing device having a debug controller that issues a context-sensitive debug request. The context-sensitive debug request includes at least one conditional criteria. A processing core receives the debug request, determines whether all of the at least one conditional criteria are true, and services the debug request when all of the at least one conditional criteria are true by accessing a data location indicated in the debug request. The servicing of the debug request may be performed in real-time mode without suspending the processing device, and the accessing can be a read or a write operation depending on the type of access indicated in the debug request. The conditional criteria may include one or more of a processor mode condition, a virtual machine identifier condition, and a debug context condition.

Abstract: A real-time debugger implementation maintains and manages multiple debug contexts allowing developers to interact with real-time applications without “breaking” the system in which the debug application is executing. The debugger allows multiple debug contexts to exist and allows break points in real-time and non-real-time code portions of one or more applications executing on a debug enabled core of a processor. A debug monitor function may be implemented as a hardware logic module on the same integrated circuit as the processor. Higher priority interrupt service requests may be serviced while otherwise maintaining a context for the debug session (e.g., stopped at a developer defined breakpoint). Accordingly, the application developer executing the debugger may not have to be concerned with processing occurring on the processor that may be unrelated to the current debug session.

Abstract: A system and method is presented for product substantiation and promotion redemption. A purchased product list is transmitted from a retail store system to a promotion analysis server along with a user identifier. The promotion analysis server identifies promotions available to the user, and then considers whether the benefits under the promotions are still available to the user. Discounts for available promotions related to the purchased product list are calculated and transmitted to the retail store system for deduction from the transactions. An approved product list can be provided that filters the purchased product list before transmittal. The approved product list can include promotions from a plurality of programs.