Abstract: The present invention relates to a pharmaceutical composition that provides long-term stability of a hydrolytically labile antipsychotic agent.

Abstract: In one aspect, a dry powder comprising respirable dry particles that comprise amorphous itraconazole in an amount of about 45% to about 75%, sodium sulfate in an amount of about 10% to about 55%, and optionally one or more other excipients, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%. In another aspect, a dry powder comprising respirable dry particles that comprise amorphous itraconazole in an amount of about 45% to about 55%, sodium chloride in an amount of about 30% to about 40%, and leucine in an amount of about 10% to about 20%, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%.

Abstract: The present invention relates to a pharmaceutical composition comprising sorbitan esters of carboxylic acids that are useful for the delivery of anti-psychotic drugs.

Abstract: Processes for providing depot injections of recrystallized aripiprazole lauroxil in which particles of the aripiprazole lauroxil have a surface area of about 0.50 to about 3.3 m2/g; and crystals of aripiprazole lauroxil produced by such processes.

Abstract: A management entity communicates over a network with devices on which security rules are configured to control network access. Data that indicates a hit count for each security rule across the devices is repeatedly collected from the devices. The indicated hit counts for each security rule are aggregated over different repeating time intervals to produce repeatedly aggregated hit counts for respective ones of the different repeating time intervals. The security rules are generated for display on a user interface screen as selectable options. Responsive to a selection of one of the security rules, a selected security rule and most recently aggregated hit counts for the different repeating time intervals for the selected security rule are generated for concurrent display on the user interface screen. The display of the most recently aggregated hit counts for the selected security rule is updated as time progresses.

Abstract: Processes for providing depot injections of recrystallized aripiprazole lauroxil in which particles of the aripiprazole lauroxil have a surface area of about 0.50 to about 3.3 m2/g; and crystals of aripiprazole lauroxil produced by such processes.

Abstract: The present invention relates to an injectable, pharmaceutical composition comprising a C1-6 alkyl ester of a C10-20 fatty acid. In an embodiment, the fatty acid is ethyl oleate, isopropyl oleate, ethyl myristate, or isopropyl myristate. These compositions are useful for the delivery of anti-psychotic drugs.

Abstract: The present invention relates to a pharmaceutical composition comprising benzyl alcohol and polyoxyethylene derivatives of sorbitan esters of carboxylic acids that are useful for the delivery of anti-psychotic drugs.

Abstract: The present invention relates to a pharmaceutical composition comprising glycerol esters of a fatty acid, wherein the compositions are useful for the delivery of anti-psychotic drugs.

Abstract: The present invention relates to a pharmaceutical composition that provides long-term stability of a hydrolytically labile antipsychotic agent.

Abstract: The present invention relates to a pharmaceutical composition that provides long-term stability of a hydrolytically labile antipsychotic agent

Abstract: A management entity communicates over a network with devices on which security rules are configured to control network access. Data that indicates a hit count for each security rule across the devices is repeatedly collected from the devices. The indicated hit counts for each security rule are aggregated over different repeating time intervals to produce repeatedly aggregated hit counts for respective ones of the different repeating time intervals. The security rules are generated for display on a user interface screen as selectable options. Responsive to a selection of one of the security rules, a selected security rule and most recently aggregated hit counts for the different repeating time intervals for the selected security rule are generated for concurrent display on the user interface screen. The display of the most recently aggregated hit counts for the selected security rule is updated as time progresses.

Abstract: The present invention relates to respirable dry powder comprising respirable dry particles that comprise sodium chloride, leucine, and tiotropium bromide, wherein the sodium chloride is about 60% to about 90%, the leucine is about 10% to about 40%, the tiotropium bromide is about 0.01% to about 0.5%, and optionally one or more additional therapeutic agents up to about 20%, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%. The invention also relates to respirable dry powders that contain respirable dry particles that comprise sodium chloride, leucine, and tiotropium bromide, wherein the sodium chloride is 67% to 84%, the leucine is 12% to 28%, the tiotropium bromide is about 0.01% to about 0.5%, and optionally one or more additional therapeutic agents up to about 20%, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%.

Abstract: Presented herein are techniques for remotely releasing bootstrap credentials to a cloud management proxy device. In particular, a cloud management proxy device that is associated with a cloud system commences a boot operation. The cloud management proxy device then initiates a remote credential release process to obtain the bootstrap credentials, which are useable by the cloud management proxy device to complete the boot operation. Upon completion of the remote credential release process, the bootstrap credentials are received from a remote credential manager system.

Abstract: The invention relates to, for example, a respirable dry powder that contains respirable dry particles that contains a tiotropium salt, one or more amino acids, sodium chloride, and optionally one or more additional therapeutic agents, where the tiotropium salt is about 0.01% to about 0.5%, the one or more amino acids is about 5% to about 40%, the sodium chloride is about 50% to about 90%, and the optional one or more additional therapeutic agents are up to about 30%, where all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%, and wherein the majority of the one or more amino acids are present in a crystalline state.

Abstract: A dry powder containing dry particles that contain a tiotropium salt, one or more amino acids, and acid content, and optionally, sodium chloride, and/or one or more additional therapeutic agents, wherein the molar ratio of acid to amino acid is from about 0.0005 to about 5, or 0.002 to about 1. In one aspect, the dry powder containing dry particles is suitable for administration to the respiratory tract. In one aspect, the dry powder containing dry particles is a respirable dry powder contains respirable dry particles that contain a tiotropium salt, one or more amino acids, acid content, sodium chloride, and optionally one or ore additional therapeutic agents, wherein the tiotropium salt is about 0.01% to about 0.5%, the leucine is about 5% to about 40%, the sodium chloride is about 50% to about 90%, the optional one or more additional therapeutic agents are up to about 30%, and the molar ratio of acid to amino acid is from about 0.

Abstract: The present invention relates to respirable dry powder comprising respirable dry particles that comprise sodium chloride, leucine, and tiotropium bromide, wherein the sodium chloride is about 60% to about 90%, the leucine is about 10% to about 40%, the tiotropium bromide is about 0.01% to about 0.5%, and optionally one or more additional therapeutic agents up to about 20%, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%. The invention also relates to respirable dry powders that contain respirable dry particles that comprise sodium chloride, leucine, and tiotropium bromide, wherein the sodium chloride is 67% to 84%, the leucine is 12% to 28%, the tiotropium bromide is about 0.01% to about 0.5%, and optionally one or more additional therapeutic agents up to about 20%, wherein all percentages are weight percentages on a dry basis and all the components of the respirable dry particles amount to 100%.

Abstract: The present invention relates to a pharmaceutical composition comprising sorbitan esters of carboxylic acids that are useful for the delivery of anti-psychotic drugs.

Abstract: A method is performed at a management device to manage multiple network security devices over a network. The security devices are configured to control access to network accessible resources. A query is received. In response to the received query, a respective native security rule that references the specific resource is collected from each security device, where each native security rule is based on a respective native rule model associated with the security device from which the native security rule is collected. Each native security rule is translated into a respective normalized rule that is based on a generic rule model. The respective normalized rules are compared to each other to generate compare results. Based on the compare results, an indication of whether each security device allows or blocks access to the specific resource is generated.

Abstract: A method is performed at a management device to manage multiple network security devices over a network. The security devices are configured to control access to network accessible resources. A query is received. In response to the received query, a respective native security rule that references the specific resource is collected from each security device, where each native security rule is based on a respective native rule model associated with the security device from which the native security rule is collected. Each native security rule is translated into a respective normalized rule that is based on a generic rule model. The respective normalized rules are compared to each other to generate compare results. Based on the compare results, an indication of whether each security device allows or blocks access to the specific resource is generated.