Abstract: The present disclosure provides gaming systems having one or more processors coupled to memory. The gaming system can receive an indication of a wager on a play of a game. The gaming system can decrease a credit balance based on the wager. The gaming system can determine a first number as a target value and a second number as a modifier. The gaming system can determine an initial award amount based on the wager and a result of the play independent of the first number. The gaming system can determine that a game event of the play satisfies a bonus award condition based on the first number. The gaming system can compute a bonus award based on the second number and the initial award amount. The gaming system can cause the credit balance to increase based on the computed bonus award and the initial award amount.

Abstract: The present disclosure provides gaming systems having one or more processors coupled to memory. The gaming system can receive an indication of a wager on a play of a game. The gaming system can decrease a credit balance based on the wager. The gaming system can determine a first number as a target value and a second number as a modifier. The gaming system can determine an initial award amount based on the wager and a result of the play independent of the first number. The gaming system can determine that a game event of the play satisfies a bonus award condition based on the first number. The gaming system can compute a bonus award based on the second number and the initial award amount. The gaming system can cause the credit balance to increase based on the computed bonus award and the initial award amount.

Abstract: Methods and compositions are provided for modulating, e.g., increasing or decreasing, the expression of telomerase reverse transcriptase (TERT). In the subject methods, the binding interaction of the TERT Site C repressor site with a Site C repressor protein complex made up of one or more proteins is modulated to achieve the desired change in TERT expression. A feature of the subject invention is that the target Site C repressor protein complex includes an LSF protein. The subject methods and compositions find use in a variety of different applications, including the immortalization of cells, the production of reagents for use in life science research, therapeutic applications; therapeutic agent screening applications; and the like.