Abstract: An amusement-type prize-play device is provided. The device includes a housing defining a prize area for containing one or more prizes for winning as a result of the play of the device, a moveable prize play mechanism, at least one player input device, a prize collection area, at least one optical prize collection sensor configured to detect the presence of a prize at the prize collection area, and a controller configured to receive the input from the player and cause the moveable prize play mechanism to move at least in part based upon the input. The controller is also configured to receive an output of the optical prize collection sensor and generate a prize-winning outcome when the optical prize collection sensor detects the prize at the prize collection area.

Abstract: The present disclosure is directed to positioning animated images within a dynamic keyboard interface. In particular, the methods and systems of the present disclosure can: receive, from a user device on which an application is executed, data indicating a context of: the application, and/or a dynamic keyboard interface provided in association with the application; identify, based at least in part on the data indicating the context, a plurality of different animated images, including an animated image comprising an advertisement, for presentation by the dynamic keyboard interface; communicate, to the user device, data indicating the plurality of different animated images; receive, from the user device, data indicating a selection of the animated image comprising the advertisement; and determine, based at least in part on the data indicating the selection and the data indicating the context, a position within the dynamic keyboard interface for presenting the animated image comprising the advertisement.

Abstract: In biosciences and related fields, it can be useful to study cells in isolation so that cells having unique and desirable properties can be identified within a heterogenous mixture of cells. Processes and methods disclosed herein provide for encapsulating cells within a microfluidic device and assaying the encapsulated cells. Encapsulation can, among othere benefits, facilitate analyses of cells that generate secretions of interest which would otherwise rapidly diffuse away or mix with the secretions of other cells.

Abstract: This disclosure provides methods for treating a subject afflicted with a tumor derived from a renal cell carcinoma. The methods comprise administering a first dose to a subject of an anti-PD-1 antibody or antigen-binding portion thereof and/or an anti-PD-L1 antibody or antigen-binding portion thereof, and administering a second dose to the subject, wherein the subject exhibited differential expression in one or more biomarker genes, e.g., CTLA-4, TIGIT, and/or PD-L2, following administration of the first dose.

Abstract: Environmentally friendly refrigerant blends utilizing refrigerants including 2,3,3,3-tetrafluoropropene (HFO-1234yf), 1,2-difluoroethylene, at least one hydrocarbon selected from the group consisting of propane, cyclopropane, propylene, isobutane, and n-butane, and optionally 1,1-difluoroethane (HFC-152a). The blends have low GWP, low toxicity, and low flammability with low temperature glide for use in a hybrid, mild hybrid, plug-in hybrid, or full electric vehicles for thermal management (transferring heat from one part of the vehicle to the other) of the passenger compartment providing air conditioning (A/C) or heating to the passenger cabin.

Abstract: In some aspects, systems and methods provide for forming groupings of a plurality of independently-specified computation workloads, such as graphics processing workloads, and in a specific example, ray tracing workloads. The workloads include a scheduling key, which is one basis on which the groupings can be formed. Workloads grouped together can all execute from the same source of instructions, on one or more different private data elements. Such workloads can recursively instantiate other workloads that reference the same private data elements. In some examples, the scheduling key can be used to identify a data element to be used by all the workloads of a grouping. Memory conflicts to private data elements are handled through scheduling of non-conflicted workloads or specific instructions and/or deferring conflicted workloads instead of locking memory locations.

Abstract: The disclosure is directed at a method and system for detecting at least one toxin in a sample using a microfluidic device. The sample is mixed with a reagent within a mixing module to generate a mixture solution. The mixture solution is then collected in a detection chamber and tested for its fluorescence. The reagent being used includes beads that have been functionalized with the toxin of interest and BSA molecules.

Abstract: In various examples, systems and methods are disclosed herein for a vehicle command operation system that may use technology across multiple modalities to cause vehicular operations to be performed in response to determining a focal point based on a gaze of an occupant. The system may utilize sensors to receive first data indicative of an eye gaze of an occupant of the vehicle. The system may utilize sensors to receive second data indicative of other data from the occupant. The system may then calculate a gaze vector based on the data indicative of the eye gaze of the occupant. The system may determine a focal point based on the gaze vector. In response to determining the focal point, the system causes an operation to be performed in the vehicle based on the second data.

Abstract: The invention provides herein epigenetics changes identified in differentially methylated regions (DMRs) of DNA of a father that are associated with the risk for an offspring having autism spectrum disorder (ASD). The invention further provides methods of determining a risk of having an offspring with ASD, methods of diagnosing ASD in a subject, and methods of determining an association between exposure to an environmental factor in a subject and an increased risk of having an offspring with ASD. The invention also provides a kit for determining whether a subject has or is at risk of having or inheriting a risk of having ASD.

Abstract: Disclosed herein is a herbicide and methods for the control of a grass or a broadleaf weed in a crop. The herbicide comprises an effective amount glufosinate, or a salt thereof, and an effective amount of a metabolic inhibitor.

Abstract: A relative risk can be determined using an originating Internet Protocol (IP) address as an identifying factor for purposes of authenticating a user. The originating IP address can be used as an identifying factor for a particular user account to determine potentially fraudulent activity and reduce the risk of fraud. This additional identifying factor can be used as a part of an overall authentication platform to help screen fraud attempts and to authenticate valid and non-fraudulent users. Using certain aspects can distinguish whether originating IP addresses are public or private. Some examples can track and match originating IP addresses to user accounts and also can keep track of recently active sessions for each IP address.

Abstract: An implant insertion tool includes an outer shaft, an inner shaft received in the outer shaft, and two arms coupled to the outer shaft and the inner shaft. The inner shaft translates within the outer shaft and has angled ramps that slide within complementary angled ramps in the two arms. The arms engage an implant for insertion into a body. When the inner shaft translates along a longitudinal axis, it causes the angled ramps to slide against the complementary angled ramps in the arms such that the two arms move laterally relative to the longitudinal axis of the outer shaft to engage and disengage the implant.

Abstract: Oral pharmaceutical compositions of sodium oxybate having improved pharmacokinetic properties when administered less than two hours after eating are provided, and therapeutic uses thereof.

Abstract: A band clamp including a housing; a screw that extends through a top surface of the housing and into a cavity defined by the housing; a band opening located within the housing and configured and dimensioned to receive a band; an inserter opening located within the housing and configured and dimensioned to receive an inserter; and an anvil located within the cavity of the housing is disclosed. A band clamp assembly, an inserter, and an inserter assembly is also disclosed. A method of inserting a band clamp is also disclosed.

Abstract: Integrated table motion includes a teleoperated device comprising an articulated structure and a control unit. The articulated structure comprises a first plurality of joints, a plurality of links coupled by the first plurality of joints, and a plurality of actuators coupled to drive motion of the articulated structure. The control unit comprises one or more hardware processors. The control unit is operatively coupled to the articulated structure. The control unit is configured to receive a table movement request from a command unit of a table, the table being separate from the teleoperated device; determine whether the table movement request should be allowed; and in response to a determination that the table movement request should be allowed, allow the table to perform the table movement request.

Abstract: Disclosed herein are serinol derivatives for capturing acid gases and methods of making and use thereof.

Abstract: Disclosed herein are gutter guard systems arranged to efficiently manage the flow of rainwater across the system and prevent the matting of debris onto the system. In one exemplary embodiment, a gutter guard system includes a main body and a screen covering the main body. The gutter guard assembly further includes a front receiver and a rear receiver that secure the screen to the main body. The screen includes at least one feature arranged to manage the flowrate of rainwater across the gutter guard system. In one example, the feature is a raised rounded area that slows the flowrate of rainwater across the gutter guard system. In another embodiment, the screen includes an upwardly angled section and a transition section. Once assembled and installed, the transition section and optionally the angled section forms hurdles that slows the flowrate of rainwater across the gutter guard system.

Abstract: A portable lighting device includes a body having an input port supported on an exterior surface of the body and an output port supported on the exterior surface of the body. The input port is operable to receive power from a power source and the output port is operable to transfer power to an external device. The portable lighting device also includes a support member coupled to the body. The support member is configured to hang the portable lighting device from a support structure. The portable lighting device further includes a lighting unit that extends downward from the body. The lighting unit is electrically coupled to the input port to receive power from the power source.

Abstract: Described herein is a thermostat that comprises a plurality of pogo pins operatively connected to a plurality of terminal tabs associated with a terminal block assembly of the thermostat. The terminal block assembly is configured in/on a mounting bracket associated with the thermostat, such that a tip of the pogo pins extends at least partially outside from a front side of the mounting bracket. The thermostat further comprises a control unit comprising a printed circuit board that comprises a plurality of electrical pads, wherein the PCB is configured within a housing that is adapted to be removably fitted on the front side of the mounting bracket, wherein the pogo pins are configured to align and engage with the electrical pads of the PCB, upon fitment of the housing on the mounting bracket. to operatively connect the electrical pads of the PCB to the terminal tabs of the terminal block assembly.

Abstract: A method includes error encoding data to produce a plurality of data slices. Metadata is determined for a data slice of the plurality of data slices. The metadata is stored in a metadata storage tree. The data slice is stored in a slice storage location indicated by the metadata. Based on determining to access the data slice, the metadata for the data slice is accessed in the metadata storage tree to determine the slice storage location for the data slice, and the data slice is accessed in the slice storage location based on determining the slice storage location for the data slice via accessing the metadata storage tree.