Abstract: Techniques for client-side caching of a medical image and server-side coordination of the client-side caching techniques are disclosed herein. User interaction in a client medical image display interface is coordinated with server conversion and processing operations. In one example, a server provides a unique key and display parameters to coordinate and specify client display operations. The unique key can be used to obtain a copy of the image from a local client-side cache, and the display parameters can be used to specify client-side transformation and rendering techniques to implement a requested image view. As a result of the client-side caching operations, resource utilization (including computational processing and network bandwidth) can be minimized, while user interactivity can be maximized.