Abstract: A venous valve with a frame and a cover on the frame for unidirectional flow of a liquid through the valve.

Abstract: The present disclosure relates generally to methods and devices for closing and/or sealing an opening in a vessel wall and/or an adjacent tissue tract. In one illustrative embodiment, a device is provided for delivering and deploying an anchor, plug, filament, and locking element adjacent to the opening in the vessel wall and/or tissue tract.

Abstract: A venous valve apparatus, system and method for valve replacement. The valve includes a valve frame, a valve leaflet joined to the valve frame, and a support frame. The valve leaflet includes surfaces defining a reversibly sealable opening for unidirectional flow of a liquid. The support frame meets the valve frame on an axis, where the valve frame and the support frame extend from the axis in an opposing direction. The system further includes a catheter, where the valve can be reversibly joined to the catheter at a location between a proximal end and a distal end of the catheter. The system can be used to deploy the valve from the catheter at a predetermined location.

Abstract: A venous valve with a frame and a cover on the frame for unidirectional flow of a liquid through the valve.

Abstract: A venous valve apparatus, system and method for valve replacement. The valve includes a valve frame, a valve leaflet joined to the valve frame, and a support frame. The valve leaflet includes surfaces defining a reversibly sealable opening for unidirectional flow of a liquid. The support frame meets the valve frame on an axis, where the valve frame and the support frame extend from the axis in an opposing direction. The system further includes a catheter, where the valve can be reversibly joined to the catheter at a location between a proximal end and a distal end of the catheter. The system can be used to deploy the valve from the catheter at a predetermined location.

Abstract: An apparatus for promoting hemostasis of a puncture formed in a blood vessel accessible through an incision tract and methods of use thereof. The apparatus includes distal and proximal balloons each having a contracted position and an expanded position, the proximal balloon spaced by a predetermined initial distance from the distal balloon. The apparatus further includes at least one catheter coupling the distal and proximal balloons to a source of pressurized fluid to selectively actuate the distal and proximal balloons between the contracted and expanded positions.

Abstract: The disclosure provides a modified arteriotomy closure plug, the modification consisting of subjecting a bioabsorbable foam closure plug to radial compression and/or axial bending until at least some struts of the foam have been torn or elongated within at least one axially disposed region.

Abstract: The disclosure provides a modified arteriotomy closure plug, said modification selected from the group consisting of a slit, a notch, a groove, and combinations thereof and a method of manufacturing the arteriotomy closure plug.

Abstract: The present disclosure relates generally to methods and devices for closing and/or sealing an opening in a vessel wall and/or an adjacent tissue tract. In one illustrative embodiment, a device is provided for delivering and deploying an anchor, plug, filament, and/or locking element adjacent to the opening in the vessel wall and/or tissue tract.

Abstract: The disclosure provides a composite arteriotomy closure plug, a method of manufacturing the composite arteriotomy closure plug, and a method for the use thereof.

Abstract: A venous valve with a frame and a cover on the frame for unidirectional flow of a liquid through the valve.

Abstract: A venous valve with a frame and a cover on the frame for unidirectional flow of a liquid through the valve.

Abstract: A venous valve with a frame and valve leaflets that provide a sinus pocket. The venous valve provides for unidirectional flow of a liquid through the valve.

Abstract: The present invention is directed to a green fluoropolymer tube which has a wall thickness of about 250 microns or less, preferably about 200 microns or less, and more preferably about 125 microns or less. With such thinness, the green tube may be formed into a tube of expanded fluoropolymer having a wall thickness of about 250 microns or less, preferably about 200 ?m or less and more preferably about 125 microns or less. Such an expanded fluoropolymer tube is particularly well-suited for use as an endovascular prosthesis, such as a graft, or in a stent-graft, because of its flexibility and strength.

Abstract: A venous valve with a frame and valve leaflets that provide a sinus pocket. The venous valve provides for unidirectional flow of a liquid through the valve.

Abstract: A composite biomaterial having a continuous metal sheet with arcuate members that define a first fenestration pattern, and a polymer layer over at least one surface of the continuous metal sheet. The arcuate members elastically stretch to allow the continuous metal sheet to bend in more than one axis without buckling or wrinkling.

Abstract: A composite biomaterial having a continuous metal sheet with arcuate members that define a first fenestration pattern, and a polymer layer over at least one surface of the continuous metal sheet. The arcuate members elastically stretch to allow the continuous metal sheet to bend in more than one axis without buckling or wrinkling.

Abstract: Apparatuses, systems, and methods for use in a vascular system. The apparatus include a circulatory valve having a valve frame in which frame members define frame cells. Frame cells include joints in opposing relationship, where the joints transition from a first stable equilibrium state through an unstable equilibrium state to a second stable equilibrium state as the joints are drawn towards each other.

Abstract: An apparatus, system, and method for percutaneous valve replacement and/or augmentation. The apparatus includes a valve having a valve frame, a valve leaflet coupled to the valve frame, and a thread passing over the valve frame to hold the valve frame in a partially deployed state, where removal of the thread allows the valve frame to expand toward a deployed state. Use of the thread to hold the valve frame allows for staged deployment of the valve.

Abstract: A blood access for dialysis includes a radially distensible support structure having an open lattice structure defining a support wall having interstitial open areas and defining exterior and luminal wall surfaces; a first porous polymeric portion having a plurality of pores, the first porous polymeric portion being securably disposed over at least a portion of the exterior wall portion of the support structure; a second porous polymeric portion having a plurality of pores, the second porous polymeric portion being securably disposed over at least a portion of the luminal portion of the support structure; and a biodegradable and/or bioabsorbable material disposed within the pores of the first polymeric portion and/or pores of the second polymeric portion.