Abstract: A processor coupled to memory is configured to receive an identification of a geographical location associated with a target specified by a user remote from a vehicle. A machine learning model is utilized to generate a representation of at least a portion of an environment surrounding the vehicle using sensor data from one or more sensors of the vehicle. At least a portion of a path to a target location corresponding to the received geographical location is calculated using the generated representation of the at least portion of the environment surrounding the vehicle. At least one command is provided to automatically navigate the vehicle based on the determined path and updated sensor data from at least a portion of the one or more sensors of the vehicle.

Abstract: Systems and methods are described herein for tracking an elongate instrument or other medical instrument in an image.

Abstract: A system and method for automated cybersecurity defensive strategy analysis that predicts the evolution of new cybersecurity attack strategies and makes recommendations for cybersecurity improvements to networked systems based on a cost/benefit analysis. The system and method use machine learning algorithms to run simulated attack and defense strategies against a model of the networked system created using a directed graph. Recommendations are generated based on an analysis of the simulation results against a variety of cost/benefit indicators.

Abstract: An electric water heater has upper and lower electric resistance type heating elements respectively controlled by a single pole, double throw upper thermostat and a single pole, single throw lower thermostat. The upper and lower thermostats are operatively interconnected by a wiring harness having outer conductor end portions that are connected to a terminal block portion of an external junction box to provide the water heater with a variety of heating element operating modes without having to replace either of the thermostats, vary the wiring harness interconnections therebetween, or vary the connection between the outer conductor end portions and the terminal block. The water heater may thus be advantageously manufactured in a single variant that may be easily and quickly modified in the field to selectively alter the heating element control mode of the water heater.

Abstract: Authorization and delivery of content may employ uniform resource signing packages. A uniform resource signing package may comprise access parameters for a content item, user, and/or device, and may be sent to the client as a uniform resource query parameter. The client may include the uniform resource signing package in future requests associated with the content item.

Abstract: Disclosed are systems and methods for encryption key management. Content items, or portions thereof, can be assigned to a plurality of partitions. Each of the plurality of partitions can correspond to a timeframe of encryption key rotation. Cache control can be applied to manifests and/or content based on the timeframe of encryption key rotation.

Abstract: Methods are described herein for screening an antibody producing cell within a microfluidic environment. The antibody producing cell may be a B cell lymphocyte, which may be a memory B cell or a plasma cell. An antigen of interest may be brought into proximity with the antibody producing cell and binding of the antigen by an antibody produced by the antibody producing cell may be monitored. Methods of obtaining a sequencing library from an antibody producing cell are also described.

Abstract: A “nanolipogel” is a delivery vehicle including one or more lipid layer surrounding a hydrogel core, which may include an absorbent such as a cyclodextrin or ion-exchange resin. Nanolipogels can be constructed so as to incorporate a variety of different chemical entities that can subsequently be released in a controlled fashion. These different incorporated chemical entities can differ dramatically with respect to size and composition. Nanolipogels have been constructed to contain co-encapsulated proteins as well as small hydrophobic drugs within the interior of the lipid bilayer. Agents incorporated within nanolipogels can be released into the milieu in a controlled fashion, for example, nanolipogels provide a means of achieving simultaneous sustained release of agents that differ widely in chemical composition and molecular weight. Additionally, nanolipogels can favorably modulate biodistribution.

Abstract: The invention relates to diagnostic and therapeutic methods for inflammatory bowel disease. Disclosed is a method of differentiating between ulcerative colitis (UC) and Crohn's disease (CD) in a subject having an inflammatory bowel disease (IBD) comprising determining a level of one or more of SEQ ID NOs: 1-590 in a sample from the subject.

Abstract: The invention relates to diagnostic and therapeutic methods for colorectal cancer.

Abstract: The invention relates to diagnostic and therapeutic methods for inflammatory bowel disease (IBD).

Abstract: Aspects of the disclosure relate to a system and method for securely authenticating a device via token(s) and/or verification computing device(s). A verification computing device may generate a pseudorandom number or sequence. Based on the pseudorandom number or sequence, the verification computing device may select a first plurality of parameters associated with a user of a device to be authenticated. The verification computing device may transmit, to the device, the pseudorandom number or sequence, and the device may select a second plurality of parameters. The device may generate a token based on the second plurality of parameters. The device may send the token to another device, and the other device may send the token to the verification computing device. The verification computing device may authenticate the device based on the token.

Abstract: Connecting to an unsecured wired or wireless network poses severe security and privacy risks. An individual application such as a mobile online banking application address this by using point to point private network connections. Browsers, however, generally do not use point to point private network connections and depend on the target website to establish a secure connection. Providing a secure connection that is the default for all network access and that encrypts all over the air or over the wire traffic mitigates these risks. However, virtual client networks (VPNs) client applications can be difficult to set up and need to be always on to ensure that all network activity is secure. By embedding a VPN capability and automating the connection process, a safe and secure network connection can be made available to users of computing devices.

Abstract: Methods, computer-readable media, software, and apparatuses may assist the user in understanding their unique digital footprint and the connections from the data within the footprint to the user's connections online and in the physical world. The determined information may be visually displayed to the user along with recommendations regarding digital safety.

Abstract: A system for harvesting solar energy on a spacecraft includes a stiff substrate layer and a working layer disposed on the substrate layer to provide at least one of a photovoltaic or a reflective function. In a first operational state, the substrate layer is arranged as a tape spring to store potential energy which causes the substrate layer to uncoil and provide, in a second operational state, a photovoltaic module and/or a solar concentrator.

Abstract: Aspects of the disclosure relate to a system and method for securely authenticating a device via token(s) and/or verification computing device(s). A verification computing device may generate a pseudorandom number or sequence. Based on the pseudorandom number or sequence, the verification computing device may select a first plurality of parameters associated with a user of a device to be authenticated. The verification computing device may transmit, to the device, the pseudorandom number or sequence, and the device may select a second plurality of parameters. The device may generate a token based on the second plurality of parameters. The device may send the token to another device, and the other device may send the token to the verification computing device. The verification computing device may authenticate the device based on the token.

Abstract: Aspects of the disclosure relate to a system and method for securely authenticating a device via token(s) and/or verification computing device(s). A verification computing device may generate a pseudorandom number or sequence. Based on the pseudorandom number or sequence, the verification computing device may select a first plurality of parameters associated with a user of a device to be authenticated. The verification computing device may transmit, to the device, the pseudorandom number or sequence, and the device may select a second plurality of parameters. The device may generate a token based on the second plurality of parameters. The device may send the token to another device, and the other device may send the token to the verification computing device. The verification computing device may authenticate the device based on the token.

Abstract: Methods, computer-readable media, software, and apparatuses may assist the user in understanding their unique digital footprint and the connections from the data within the footprint to the user's connections online and in the physical world. The determined information may be visually displayed to the user along with recommendations regarding digital safety.

Abstract: The invention relates to physiologically acceptable compositions of isolated microorganisms, lysates thereof, and supernatants therefrom, as well as methods of their use and preparation.

Abstract: Methods, computer-readable media, software, and apparatuses may assist the user in understanding their unique digital footprint and the connections from the data within the footprint to the user's connections online and in the physical world. The determined information may be visually displayed to the user along with recommendations regarding digital safety.