Abstract: A transcatheter pulmonary flow reduction device for treating patients with congenital cardiac conditions and methods for making and using same. The transcatheter pulmonary flow reduction device comprises an hourglass-shaped device frame with a proximal end region, an intermediate waist region and a distal end region that cooperate to define an internal channel. The device frame is deployed within a pulmonary artery of a patient and expanded such that the proximal and distal end regions engage the pulmonary artery and the internal channel of the waist region has a first expanded cross-section for restricting blood flow. Later, the waist region of the deployed device frame is further expanded for increasing the internal channel of the waist region from the first expanded cross-section to a second expanded cross-section that is greater than the first cross-section. The transcatheter pulmonary flow reduction device thereby adjusts the restricted blood flow through the pulmonary artery.