Patents by Inventor Jason R. Killough

Jason R. Killough has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized Aptamers to PSMA and Their Use as Prostate Cancer Therapeutics
    Publication number: 20090105172
    Abstract: The present invention provides stabilized, high affinity nucleic acid ligands to PSMA. Methods for the identification and preparation of novel, stable, high affinity ligands to PSMA using the SELEX™ method with 2?-O-methyl substituted nucleic acids, and cell surface SELEX™ are described herein. Also included are methods and compositions for the treatment and diagnosis of disease characterized by PSMA expression, using the described nucleic acid ligands.
    Type: Application
    Filed: March 7, 2006
    Publication date: April 23, 2009
    Inventors: John L. Diener, Paul Hatala, Jason R. Killough, Jess Wagner-Whyte, Charles Wilson, Shuhao Zhu