Patents by Inventor Jason R. Rose

Jason R. Rose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Suppression of proteolytic activity by dysfunctional protease formation
    Patent number: 6165794
    Abstract: The present invention provides recombinant vectors comprising polynucleotides encoding defective monomers of HIV (e.g., HIV-1 or HIV-2) protease which are used to interfere with viral maturation. The defective monomers result in the formation of inactive protease heterodimers and thus inhibit the polyprotein processing events that are essential for viral maturation and infectivity.
    Type: Grant
    Filed: November 10, 1994
    Date of Patent: December 26, 2000
    Assignee: The Regents of the University of California
    Inventors: Charles S. Craik, Lilia M. Babe, Jason R. Rose