Abstract: A trailer hitch system for equalizing trailer loads and reducing trailer sway. The trailer hitch system may include spring bars that may be attached to a hitch head using a trunnion style connection. The spring bars may be attached to the trailer using rigid brackets that reduce swinging of the spring bars. The rigid brackets having a plurality of contact points may include an upward extending portion for attaching to the trailer tongue, and a lateral extending portion for receiving the spring bars thereupon. The rigid brackets may include a spacing member and an attachment member.

Abstract: Various lactam compound that binds Cbl-B, many of which are selective for Cbl-B over C-Cbl, and methods of making and using the same.

Abstract: A system that incorporates the subject disclosure may include, for example, a processor that facilitates a performance of operations. The operations may include obtaining an identification of an action to monitor during a gameplay associated with a game, storing a representation of a sliding window of the gameplay in a first storage medium, monitoring, by the system, for the identification of the action during the gameplay, detecting the identification of the action during the gameplay responsive to the monitoring, and responsive to the detecting, storing the representation of the sliding window of the gameplay in a second storage medium that is different from the first storage medium. Additional embodiments are disclosed.

Abstract: A filter unit is disclosed that increases solids loading capacity, decreases specific flowrate during filtration, and improves backwash effectiveness. A flow shaping plate and/or flow diverting member are used to reduce flow entrance effects during reverse, backwash flow through the filter unit.

Abstract: A macroencapsulation device includes a frame, a first membrane layer, a second membrane layer disposed on the first membrane layer, and an interior volume between the first and second membrane layers. The interior volume can encapsulate a population of cells. The frame includes a fill port extending from an exterior of the frame to an interior of the frame, with two slots formed in the frame on opposing sides of the fill port. The slots are formed on an interior portion of the frame. The first and second membrane layers are bonded together by a seal, which extends around and defines part of a perimeter of the interior volume. The seal includes two projections disposed in the two slots of the frame. A method of manufacturing includes bonding two membrane layers to form a seal defining a perimeter of an interior volume, and inserting the projections into the slots.

Abstract: This disclosure relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.

Abstract: Droplet interfaces are formed between droplets in an electro-wetting device comprising an array of actuation electrodes. Actuation signals are applied to selected actuation electrodes to place the droplets into an energised state in which the shape of the droplets is modified compared to a shape of the droplets in a lower energy state and to bring the two droplets into proximity. The actuation signals are then changed to lower the energy of the droplets into the lower energy state so that the droplets relax into the gap and the two droplets contact each other thereby forming a droplet interface. The use of sensing electrodes in the device permit electrical current measurements across the droplet interface. The sensing electrodes can be used for either (i) applying a reference signal during droplet actuation or (ii) recording electrical current measurements.

Abstract: Techniques are described for determining whether snow chains are permitted to be used and to deploy snow chains based on traffic signs, weather conditions, and/or road conditions. An example method of autonomous driving operation includes performing a first determination, by a computer located in an autonomous vehicle, whether a use of snow chains is permitted based at least on a location where the autonomous vehicle is operating, performing a second determination that snow chains are required for driving the autonomous vehicle on a road, and sending, in response to the first determination indicating that the use of snow chains is permitted and in response to the second determination, instruction to snow chain devices located on the autonomous vehicle, where the instruction triggers the snow chain devices to deploy snow chains on tires of the autonomous vehicle.

Abstract: Embodiments of the microwave amplification system are described. In an embodiment, a microwave amplification system includes a microwave amplifier that contains a paramagnetic material with an impurity. The impurity has a plurality of nuclear spin and electron spin-based energy levels. The system includes an input to receive a pumping signal which is transmitted to the microwave amplifier to cause a population inversion in the impurity and excite it to one of the nuclear spin and electron spin-based energy levels. The system further includes another input to receive an input signal to be amplified by the microwave amplifier, the input signal having a lower power than the pumping signal. Once transmitted to the microwave amplifier, the input signal is amplified by the excited state of the impurity in the microwave amplifier thereby generating an amplified signal.

Abstract: Each of a plurality of landing pads is sized and shaped to accommodate an AV. Landing pad sensor(s) are located in or around each landing pad. A control subsystem receives landing pad sensor data from the one or more landing pad sensors and receives, from a first AV traveling to a location of the plurality of landing pads, a request for an assigned landing pad in which the first AV should park. In response to this request, the control subsystem determines, based on the received landing pad sensor data, whether a first landing pad is free of obstructions that would prevent receipt of the first AV. If the first landing pad is free of obstructions, an indication is provided to the AV that the first landing pad is the assigned landing pad.

Abstract: This disclosure relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.

Abstract: A failsafe valve system configured to bring the valve to a predefined state (e.g., fully opened, fully closed) if the actuator fails (e.g., loss of power). The failsafe system of the present disclosure is energy efficient and reliable.

Abstract: This disclosure relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.

Abstract: The present disclosure provides a system for providing personalization for a target website. The system comprises: an artificial intelligence (AI) engine including one or more machine learning algorithm trained models for providing one or more personalization features; and a personalization module configured for integrating the one or more personalization features into the target website, wherein the one or more personalization features are rendered within a popup widget displayed over the target website.

Abstract: A gas monitor configured to monitor at least one target gas in an environmental mixture, by separating and concentrating the target gas and then adjusting for the concentration factor. The adjustment may also take into account sensor sensitivities to other gases. Methods for adjustment of target gas results are described.

Abstract: A fuel theft prevention system for a vehicle including: at least one processor; and a memory, operatively connected to the at least one processor and storing instructions that, when executed by the at least one processor, cause the system to: receive, from a first sensing system, first activity data; determine, based on the first activity data, a first confidence value indicative of whether the activity is suspicious; receive fuel data indicative of a fuel level in the fuel tank; and cause, based on the first activity data and the fuel data, at least one mitigation action to be taken when the fuel level decreases by a threshold amount, wherein the threshold amount includes a first amount when the first confidence value is a first value and a second amount when the first confidence value is below the first value, and wherein the second amount is greater than the first amount.

Abstract: A surgical robotics method includes capturing points along a surface of a cutting tool by tracking a probe, deriving a tool axis from relative locations of the points, and controlling, using the tool axis, a robot that interfaces with the cutting tool.

Abstract: An array of membranes comprising amphipathic molecules is formed using an apparatus comprising a support defining an array of compartments. Volumes comprising polar medium are provided within respective compartments and a layer comprising apolar medium is provided extending across the openings with the volumes. Polar medium is flowed across the support to displace apolar medium and form a layer in contact with the volumes, forming membranes comprising amphipathic molecules at the interfaces. In one construction of the apparatus, the support that comprises partitions which comprise inner portions and outer portions. The inner portions define inner recesses without gaps therebetween that are capable of constraining the volumes comprising polar medium contained in neighbouring inner recesses from contacting each other. The outer portions extend outwardly from the inner portions and have gaps allowing the flow of an apolar medium across the substrate.

Abstract: A docking station for micromobility transit vehicles is provided. The docking station may include a rack configured to dock a micromobility transit vehicle, a bollard for securing the micromobility transit vehicle within the rack, and a dock module configured to detect a characteristic of a lock cable securing the micromobility transit vehicle to the bollard. The dock module may include an inductive coil assembly disposed around a hole of the bollard to detect the lock cable inserted into the hole.

Abstract: A compound, of formula (I): suitable for treating a cancer wherein the cancer is susceptible to inhibition of Cbl-B.