Patents by Inventor Jason Rouse

Jason Rouse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR IMPROVING RECOMBINANT PROTEIN PRODUCTION
    Publication number: 20110038863
    Abstract: Nucleic acid molecules modified to enhance recombinant protein, e.g., antibody, expression and/or reduce or eliminate mis-spliced and/or intron read-through (IRT) by-products are disclosed. The invention also provides methods for producing proteins devoid of mis-spliced and/or intron read-through by-products by the use of such vectors in host cells under cell culture conditions suitable for recombinant protein expression.
    Type: Application
    Filed: September 24, 2010
    Publication date: February 17, 2011
    Inventors: Martin S. Sinacore, Mark Leonard, Haley A. Laken, Jason Rouse
  • Methods and compositions for improving recombinant protein production
    Patent number: 7807804
    Abstract: Nucleic acid molecules modified to enhance recombinant protein, e.g., antibody, expression and/or reduce or eliminate mis-spliced and/or intron read-through (IRT) by-products are disclosed. The invention also provides methods for producing proteins devoid of mis-spliced and/or intron read-through by-products by the use of such vectors in host cells under cell culture conditions suitable for recombinant protein expression.
    Type: Grant
    Filed: October 5, 2005
    Date of Patent: October 5, 2010
    Assignee: Wyeth LLC
    Inventors: Martin S. Sinacore, Mark Leonard, Haley A. Laken, Jason Rouse
  • Methods and compositions for improving recombinant protein production
    Publication number: 20090285806
    Abstract: Nucleic acid molecules modified to enhance recombinant protein expression, e.g., that of A? peptide binding antibodies, and/or to reduce or eliminate mis-spliced and/or intron read-through (IRT) by-products are disclosed. The invention also provides methods for producing A? peptide binding antibodies devoid of mis-spliced and/or intron read-through by-products by expression of such nucleic acid molecules under cell culture conditions suitable for recombinant A? peptide binding antibody expression.
    Type: Application
    Filed: October 5, 2005
    Publication date: November 19, 2009
    Inventors: Martin Sinacore, Jason Rouse
  • Methods and compositions for improving recombinant protein production
    Publication number: 20060099206
    Abstract: Nucleic acid molecules modified to enhance recombinant protein, e.g., antibody, expression and/or reduce or eliminate mis-spliced and/or intron read-through (IRT) by-products are disclosed. The invention also provides methods for producing proteins devoid of mis-spliced and/or intron read-through by-products by the use of such vectors in host cells under cell culture conditions suitable for recombinant protein expression.
    Type: Application
    Filed: October 5, 2005
    Publication date: May 11, 2006
    Inventors: Martin Sinacore, Mark Leonard, Haley Laken, Jason Rouse