Abstract: A modular wing, adapted to be used on a flying device such as a toy airplane, drone, or other small fixed wing flying device, or form a part of a wind turbine or any other apparatus that requires a wing or blade, that is compatible with all block-based toy systems such as LEGO®, DECOOL® or KAZI®. The modular wing is comprised of a series of modular aerodynamic surfaces that may be suitable for manufacture by a low-cost method such as molding or additive manufacturing such as 3D printing, typically but not necessarily from plastic, to form wing sub elements which, when assembled together, form a wing or blade such as an airplane wing or turbine blade. The modular wing may comprise cambered or symmetric wing shapes. The modular wing may be used in a static display model fully flying aerodynamic aircraft, sailing hydrodynamic boat, or aerodynamic functioning turbine.

Abstract: This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) having core structure (I), pharmaceutical compositions containing at least one such modulator, methods of treatment of CFTR mediated diseases, including cystic fibrosis, using such modulators and pharmaceutical compositions, combination pharmaceutical compositions and combination therapies employing those modulators, and processes and intermediates for making such modulators.

Abstract: A database system is operable to determine a query for execution. A disjunction of a plurality of conjunctive normal form (CNF) filtering predicates is determined based on filtering predicates of the query. An IO pipeline is generated based on the disjunction of the plurality of CNF filtering predicates that includes, based on applying at least one type of optimization, at least one shared IO element common to multiple ones of plurality of the CNF filtering predicates. The IO pipeline is executed in accordance with execution of the query to generate a filtered subset of a plurality of rows that each meet at least one of the plurality of CNF filtering predicates.

Abstract: A novel maize variety designated X18N926 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X18N926 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X18N926 through backcrossing or genetic transformation, and to the maize seed, plant and plant part produced thereby are described. Maize variety X18N926, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X18N926 are provided. Methods for producing maize varieties derived from maize variety X18N926 and methods of using maize variety X18N926 are disclosed.

Abstract: Exemplary embodiments of the present disclosure can include, for example, an atomic force microscopy (AFM) system, including a cantilever(s), an optical pickup unit(s) (OPU(s)) including a laser positioned over the cantilever(s), and a power source providing noise with a noise level that is below 300 Picometers. The noise level of the power source can be below 200 Picometers. A digitizing arrangement can be included which can be associated with the OPU. The digitizing arrangement(s) can have a bandwidth of about 2 MHZ. The OPU(s) can have a detection bandwidth of at least 80 MHZ. The exemplary apparatus can be combined with a chemical protocol and statistical signal processing and image analysis procedures to map DNA at high speed and accuracy.

Abstract: Methods, systems, and devices for content recommendation are described. A device may receive physiological data associated with a user from a wearable device. The device may receive classifier data indicating an activity in which the user engaged. The classifier data is provided by the user via a graphical user interface (GUI) of the device running an application. The device may correlate the received physiological data and the received classifier data associated with the activity in which the user engaged, and select content for recommending to the user. The content may correspond to a respective effectiveness for regulating the received physiological data. The device may cause the GUI of the device to display the selected content for recommending to the user.

Abstract: A modular wing, adapted to be used on a flying device such as a toy airplane, drone, or other small fixed wing flying device, or form a part of a wind turbine or any other apparatus that requires a wing or blade, that is compatible with all block-based toy systems such as LEGO®, DECOOL® or KAZI®. The modular wing is comprised of a series of modular aerodynamic surfaces that may be suitable for manufacture by a low-cost method such as molding or additive manufacturing such as 3D printing, typically but not necessarily from plastic, to form wing sub elements which, when assembled together, form a wing or blade such as an airplane wing or turbine blade. The modular wing may comprise cambered or symmetric wing shapes. The modular wing may be used in a static display model fully flying aerodynamic aircraft, sailing hydrodynamic boat, or aerodynamic functioning turbine.

Abstract: Methods, systems, and devices for content delivery are described. A device may receive biometric data associated with a user from a wearable device, and receive application data associated with the user from the device. The application data may be indicative of a previous activity in which the user engaged or an upcoming activity in which the user is to engage. The device may determine content for recommending to the user based on correlating the received biometric data and the received application data. The content may correspond to a respective effectiveness for regulating the received biometric data. In some examples, the content may facilitate improvements to the user’s health and wellness. The device may cause a graphical user interface (GUI) of the device running an application to display the content for recommending to the user based on correlating the received biometric data and the received application data.

Abstract: A low stall or minimum control speed aircraft comprising a fuselage that has vertically flat sides; wings with high a lift airfoil profile of constant chord section set at zero degree planform sweep, twin booms having inner vertically flat surfaces, twin vertical stabilizers, a flying horizontal stabilizer; preferably twin engines having propellers and wherein each engine preferably has a thrust-line that is inclined nose-up to a maximum of +8 degrees, and is parallel to the wing chord underneath wing mounts and landing gear doors that provide surfaces for channeling propeller wash in a rearward direction; all working in concert so that the airplane has an extremely low stall speed and minimum control speed. The engines may be diesel, hydrogen fuel cell, electric fuel cell, diesel-electric, gas turbine or combinations thereof. The propellers may be counter-rotating.

Abstract: The clean-out cap locator forms a cap that encloses a clean-out plug. The clean-out cap locator comprises a threaded cap, a control circuit, a remote control, and a personal data device. The control circuit determines the GPS coordinates of the control circuit. The control circuit transmits the GPS coordinates of the control circuit to the personal data device. The control circuit generates an audible alarm indicating the location of the clean-out cap locator. The control circuit senses the flow of fluid around near the clean-out cap locator. The control circuit transmits an alarm to the personal data device when the control circuit senses a back-up in the clean-out plug. The control circuit generates an audible alarm when the control circuit detects a back-up in the clean-out plug. The remote control sends a signal to the control circuit that causes the control circuit to generate an audible alarm.

Abstract: Methods, systems, and devices for content delivery are described. A device may receive biometric data associated with a user from a wearable device. The device may determine that a biometric parameter of a set of biometric parameters associated with the biometric data satisfies a threshold during an occasion. The device may select media content from a set of media content for recommending to the user. Each respective media content of the set of media content may be scored based on a respective effectiveness associated with each respective media content for controlling a value of the biometric parameter. The selecting may be triggered based on the biometric parameter satisfying the threshold. The media content may be selected based on a score associated with the media content. The device may output the media content via a graphical user interface (GUI) of the apparatus during the occasion.

Abstract: The present disclosure relates to the field of pharmacy, particularly to a Wnt inhibitor and a PD-1 inhibitor for use in the treatment of cancer. Specifically, the disclosure relates to a pharmaceutical combination comprising a Wnt inhibitor, or a pharmaceutically acceptable salt thereof, and a PD-1 inhibitor, or a pharmaceutically acceptable salt thereof, for use in the treatment of cancer, to a method for the treatment of cancer that involves administering the combination and to the use of the combination for the manufacture of a medicament for the treatment of cancer.

Abstract: A modular wing, adapted to be used on a flying device such as a toy airplane, drone, or other small fixed wing flying device, or form a part of a wind turbine or any other apparatus that requires a wing or blade, that is compatible with all block-based toy systems such as LEGO®, DECOOL® or KAZI®. The modular wing is comprised of a series of modular aerodynamic surfaces that may be suitable for manufacture by a low-cost method such as molding or additive manufacturing such as 3D printing, typically but not necessarily from plastic, to form wing sub elements which, when assembled together, form a wing or blade such as an airplane wing or turbine blade. The modular wing may comprise cambered or symmetric wing shapes. The modular wing may be used in a static display model fully flying aerodynamic aircraft, sailing hydrodynamic boat, or aerodynamic functioning turbine.

Abstract: The present disclosure relates to the field of pharmacy, particularly to a Wnt inhibitor and a PD-1 inhibitor for use in the treatment of cancer. Specifically, the disclosure relates to a pharmaceutical combination comprising a Wnt inhibitor, or a pharmaceutically acceptable salt thereof, and a PD-1 inhibitor, or a pharmaceutically acceptable salt thereof, for use in the treatment of cancer, to a method for the treatment of cancer that involves administering the combination and to the use of the combination for the manufacture of a medicament for the treatment of cancer.

Abstract: A modular wing, adapted to be used on a flying device such as a toy airplane, drone, or other small fixed wing flying device, or form a part of a wind turbine or any other apparatus that requires a wing or blade, that is compatible with all block-based toy systems such as LEGO®, DECOOL® or KAZI®. The modular wing is comprised of a series of modular aerodynamic surfaces that may be suitable for manufacture by a low-cost method such as molding or additive manufacturing such as 3D printing, typically but not necessarily from plastic, to form wing sub elements which, when assembled together, form a wing or blade such as an airplane wing or turbine blade. The modular wing may comprise cambered or symmetric wing shapes. The modular wing may be used in a static display model fully flying aerodynamic aircraft, sailing hydrodynamic boat, or aerodynamic functioning turbine.

Abstract: The present disclosure relates to the field of pharmacy, particularly to a Wt inhibitor and a PD-1 inhibitor for use in the treatment of cancer. Specifically, the disclosure relates to a pharmaceutical combination comprising a Wnt inhibitor, or a pharmaceutically acceptable salt thereof, and a PD-1 inhibitor, or a pharmaceutically acceptable salt thereof, for use in the treatment of cancer, to a method for the treatment of cancer that involves administering the combination and to the use of the combination for the manufacture of a medicament for the treatment of cancer.

Abstract: A low stall or minimum control speed aircraft comprising a fuselage that has vertically flat sides; wings with high a lift airfoil profile of constant chord section set at zero degree planform sweep, twin booms having inner vertically flat surfaces, twin vertical stabilizers, a flying horizontal stabilizer; preferably twin engines having propellers and wherein each engine preferably has a thrust-line that is inclined nose-up to a maximum of +8 degrees, and is parallel to the wing chord underneath wing mounts and landing gear doors that provide surfaces for channeling propeller wash in a rearward direction; all working in concert so that the airplane has an extremely low stall speed and minimum control speed. The engines may be diesel, hydrogen fuel cell, electric fuel cell, diesel-electric, gas turbine or combinations thereof. The propellers may be counter-rotating.

Abstract: A hydrocarbon production process comprising operating a first early stage hydrocarbon production process within a first communication domain with a first well pair, and operating a second early stage hydrocarbon production process within a second communication domain with a second well pair, such that an intermediate reservoir region including stranded bitumen becomes disposed between the first and second communication domains; wherein the first early stage hydrocarbon production process includes injecting a first production-initiating fluid via a first injection well of the first well pair into a first communication domain such that hydrocarbon material is mobilized and conducted to a first production well of the first well pair, and producing the received hydrocarbon material via the first production well; and wherein the second early stage hydrocarbon production process includes injecting a second production-initiating fluid via a second injection well of the second well pair into a second communication do

Abstract: A vacuum chamber system is provided which includes a vacuum chamber body, a lid, and an elastomeric sealing element. The elastomeric sealing may be positioned about the lid. The elastomeric sealing element includes a body having a base portion positioned between a first arm and a second arm. Each of the first and second arms have inner lid contacting surfaces and outer surfaces. The elastomeric sealing element has a generally U-shaped transverse cross-section defined by the base portion and the first and second arms, and is generally reversible between first and second configurations.

Abstract: A vacuum chamber system is provided which includes a vacuum chamber body, a lid, and an elastomeric sealing element. The elastomeric sealing may be positioned about the lid. The elastomeric sealing element includes a body having a base portion positioned between a first arm and a second arm. Each of the first and second arms have inner lid contacting surfaces and outer surfaces. The elastomeric sealing element has a generally U-shaped transverse cross-section defined by the base portion and the first and second arms, and is generally reversible between first and second configurations.