Patents by Inventor Jason S. Milligan

Jason S. Milligan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9974302
    Abstract: The present invention provides novel insecticidal proteins active against a Coleopteran and/or Hemipteran species pest, which include, but are not limited to, TIC3131, TIC3400 and TIC3407 proteins. The present invention also provides a DNA construct comprising operably linked to a heterologous promoter a polynucleotide that encodes the novel insecticidal protein or an insecticidal fragment thereof. The present invention further provides transgenic plants/plant cells/plant parts expressing the insecticidal proteins, methods for detecting the presence of the polynucleotide or the protein in a biological sample, and methods of controlling a Coleopteran and/or Hemipteran species pest using the insecticidal proteins.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: May 22, 2018
    Assignee: Monsanto Technology LLC
    Inventors: Heather M. Anderson, David J. Bowen, Catherine A. Chay, Stanislaw Flasinski, Uma R. Kesanapalli, Jason S. Milligan, Rachael N. Slightom, Yong Yin
  • Patent number: 9957524
    Abstract: The invention generally relates to the field of insect inhibitory toxin proteins. A novel class of proteins exhibiting insect inhibitory activity against agriculturally relevant pests of crop plants and seeds are disclosed. Insecticidal activity is particularly effective against the Coleopteran order of insect pests. Plants, plant parts, and seed are provided containing a polynucleotide construct encoding one or more of the toxin proteins disclosed herein. The proteins are referred to herein variously as the TIC2463-related toxin protein class or family, the TIC2463-related toxin proteins, the TIC2463-related protein genus, toxin proteins related to the TIC2463 toxin protein, proteins related to TIC2463, TIC2463-related toxin polypeptides, TIC2463-related pesticidal proteins, and the like.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: May 1, 2018
    Assignee: Monsanto Technology LLC
    Inventors: David J. Bowen, Catherine A. Chay, Stanislaw Flasinski, Xiaoran Fu, Uma R. Kesanapalli, Jason S. Milligan, Rachael N. Slightom, Daqi Tu, Andrew M. Wollacott, Yong Yin
  • Publication number: 20160319302
    Abstract: Insecticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC3668, TIC3669, TIC3670, TIC4076, TIC4078, TIC4260, TIC4346, TIC4826, TIC4861, TIC4862, TIC4863, and TIC-3668-type proteins. DNA molecules and constructs are provided which contain a polynucleotide sequence encoding one or more of the disclosed TIC3668-type proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain polynucleotide sequences encoding the insecticidal proteins of the present invention. Methods for detecting the presence of the polynucleotides or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC3668-type insecticidal proteins are also provided.
    Type: Application
    Filed: November 18, 2015
    Publication date: November 3, 2016
    Inventors: Gregory J. Bean, David J. Bowen, Catherine A. Chay, Arlene R. Howe, Jason S. Milligan, Yong Yin
  • Publication number: 20150274786
    Abstract: The invention generally relates to the field of insect inhibitory toxin proteins. A novel class of proteins exhibiting insect inhibitory activity against agriculturally relevant pests of crop plants and seeds are disclosed. Insecticidal activity is particularly effective against the Coleopteran order of insect pests. Plants, plant parts, and seed are provided containing a polynucleotide construct encoding one or more of the toxin proteins disclosed herein. The proteins are referred to herein variously as the TIC2463-related toxin protein class or family, the TIC2463-related toxin proteins, the TIC2463-related protein genus, toxin proteins related to the TIC2463 toxin protein, proteins related to TIC2463, TIC2463-related toxin polypeptides, TIC2463-related pesticidal proteins, and the like.
    Type: Application
    Filed: March 27, 2015
    Publication date: October 1, 2015
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: David J. Bowen, Catherine A. Chay, Stanislaw Flasinski, Xiaoran Fu, Uma R. Kesanapalli, Jason S. Milligan, Rachael N. Slightom, Daqi Tu, Andrew M. Wollacott, Yong Yin
  • Publication number: 20150047076
    Abstract: The present invention provides novel insecticidal proteins active against a Coleopteran and/or Hemipteran species pest, which include, but are not limited to, TIC3131, TIC3400 and TIC3407 proteins. The present invention also provides a DNA construct comprising operably linked to a heterologous promoter a polynucleotide that encodes the novel insecticidal protein or an insecticidal fragment thereof. The present invention further provides transgenic plants/plant cells/plant parts expressing the insecticidal proteins, methods for detecting the presence of the polynucleotide or the protein in a biological sample, and methods of controlling a Coleopteran and/or Hemipteran species pest using the insecticidal proteins.
    Type: Application
    Filed: August 8, 2014
    Publication date: February 12, 2015
    Applicant: Monsanto Technology LLC
    Inventors: Heather M. Anderson, David J. Bowen, Catherine A. Chay, Stanislaw Flasinski, Uma R. Kesanapalli, Jason S. Milligan, Rachael N. Slightom, Yong Yin
  • Publication number: 20090263871
    Abstract: The invention provides an Enzyme Blend comprising a DNA polymerase and a DNA repair enzyme. Methods and kits for amplification of DNA that is damaged, undamaged, or suspected of being damaged are also provided.
    Type: Application
    Filed: June 23, 2009
    Publication date: October 22, 2009
    Applicant: SIGMA-ALDRICH CO.
    Inventors: Christopher L. Walker, Ernest J. Mueller, Kevin J. Kayser, Jason S. Milligan, Erik R. Eastlund