Abstract: An instrument for deploying a surgical implant includes a handle, a shaft, and a frame arm coupled to the shaft. A magnetic clip system is disposed on the frame arm for releasably retaining a surgical implant to the frame arm. The magnetic clip system includes a clip, a first ferromagnetic member, and a second ferromagnetic member. The magnetic clip system biases the clip towards a closed position.

Abstract: A mesh deployment device having separate mesh deployment and actuation units is provided. A mesh deployment device includes an actuation unit and a mesh deployment unit configured to be releasably secured to the actuation unit. When the mesh deployment unit is secured to the actuation unit, a first actuation of the actuation unit moves the mesh deployment unit from an expanded condition to a collapsed condition and a second actuation of the actuation unit moves the mesh deployment unit from the collapsed condition to the expanded condition. The mesh deployment device may further include a mesh releasably secured to the mesh deployment unit. A third actuation of the actuation unit may release the mesh from the mesh deployment unit. Also provided is a kit including multiple mesh deployment units.

Abstract: Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.

Abstract: Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.

Abstract: An instrument for deploying a surgical implant includes a handle, an elongated shaft extending from the handle, and a frame arm. The frame arm includes a clip pair for releasably attaching the surgical implant to the frame arm. The clip pair includes first and second clips operably coupled by a spring member. The first and second clips are repositionable from a closed position to an open position. The spring member biases the first and second clips towards the closed position. A lock bar is coupled to the frame arm and translatable between an unlocked position and a locked position. In the locked position, the lock bar maintains the first and second clips in either the open or the closed position. When the lock bar is in the unlocked position, the first and second clips are freely rotatable between the open and closed positions.

Abstract: A system for closing an aperture in a biological tissue includes an implant deployment device having a frame arm, a clip connected to the frame arm, and a lock bar including a protrusion. The protrusion extends away from the frame arm and is configured for selectively holding the clip in an open position or a closed position. A surgical implant is releasably attached to the frame arm. The clip retains the surgical implant in contact with the frame arm when the clip is in the closed position and the clip allows the surgical implant to be separated from the frame arm when the clip is in the open position.

Abstract: An instrument for deploying a surgical implant includes a handle, a shaft, and a frame arm coupled to the shaft. A magnetic clip system is disposed on the frame arm for releasably retaining a surgical implant to the frame arm. The magnetic clip system includes a clip, a first ferromagnetic member, and a second ferromagnetic member. The magnetic clip system biases the clip towards a closed position.

Abstract: A surgical device for deploying a surgical implant includes a proximal portion and a distal portion. The distal portion includes a frame arm. A spring clip system is coupled to the frame arm and includes a pair of clips and a spring member. The spring member is connected to each of the clips and biases the clips towards a closed position. In the closed position, the clips are configured to retain the implant in contact with the frame arm.

Abstract: Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis.

Abstract: An opto-electronic package is provided for mounting on a module base. The package comprises a generally rectangular package. An optical connector extends from a first side of the package body along an optical axis, generally parallel to the module base. A radio frequency connector extends from a second side of the package body along a RF axis, generally parallel to the module base. A plurality of electronic leads and mounting tabs each extend from at least one of the second side and a third side of the package body. A fourth side of the package body is adjacent the first side and free of connectors, leads, and mounting tabs for mounting the package in a corner of the module formed by first and second module walls. The fourth wall of the package body is positioned adjacent the first module wall and the optical connector extends through the second module wall.

Abstract: An opto-electronic package is provided for mounting on a module base. The package comprises a generally rectangular package. An optical connector extends from a first side of the package body along an optical axis, generally parallel to the module base. A radio frequency connector extends from a second side of the package body along a RF axis, generally parallel to the module base. A plurality of electronic leads and mounting tabs each extend from at least one of the second side and a third side of the package body. A fourth side of the package body is adjacent the first side and free of connectors, leads, and mounting tabs for mounting the package in a corner of the module formed by first and second module walls. The fourth wall of the package body is positioned adjacent the first module wall and the optical connector extends through the second module wall.