Patents by Inventor Jason William Soares

Jason William Soares has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for discovering one or more peptides adapted for specific binding to a microorganism of interest
    Patent number: 7033769
    Abstract: A method for discovering one or more peptides adapted for specific binding to a microorganism of interest. The method comprises (i) identifying an antimicrobial peptide having antimicrobial activity against the microorganism of interest, (ii) generating a library of first generation mutants of the antimicrobial peptide, each of the first generation mutants differing from the antimicrobial peptide by a small number of amino acid substitutions, additions or deletions, (iii) screening the library of first generation mutants for those first generation mutants that bind to the microorganism of interest, (iv) determining the peptide sequences of those first generation mutants that bind to the microorganism of interest, and (v) if necessary, repeating steps (ii) through (iv) for one or more successive generations of mutants until one or more consensus peptide sequences emerge.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: April 25, 2006
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Charlene M. Mello, Steven Michael Arcidiacono, Jason William Soares
  • Method for discovering one or more peptides adapted for specific binding to a microorganism of interest
    Publication number: 20040224358
    Abstract: A method for discovering one or more peptides adapted for specific binding to a microorganism of interest. The method comprises (i) identifying an antimicrobial peptide having antimicrobial activity against the microorganism of interest, (ii) generating a library of first generation mutants of the antimicrobial peptide, each of the first generation mutants differing from the antimicrobial peptide by a small number of amino acid substitutions, additions or deletions, (iii) screening the library of first generation mutants for those first generation mutants that bind to the microorganism of interest, (iv) determining the peptide sequences of those first generation mutants that bind to the microorganism of interest, and (v) if necessary, repeating steps (ii) through (iv) for one or more successive generations of mutants until one or more consensus peptide sequences emerge.
    Type: Application
    Filed: May 23, 2002
    Publication date: November 11, 2004
    Inventors: Charlene M. Mello, Steven Michael Arcidiacono, Jason William Soares