Patents by Inventor Jason Y.H. Chang

Jason Y.H. Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids
    Patent number: 12018315
    Abstract: The present disclosure relates to a device, comprising a base and a plurality of microneedles attached to the base, wherein each microneedle has an outer surface; the outer surface of at least one microneedle being coated with a composition comprising at least one polymer and least one Peptide Nucleic Acid (PNA). The present disclosure additionally relates to a method of detecting an analyte in interstitial fluid (ISF), comprising contacting the device to a subject, for example, to human skin.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: June 25, 2024
    Assignees: Massachusetts Institute of Technology, Imperial College Innovations Limited
    Inventors: Darrell J. Irvine, Jason Y. H. Chang, Sylvain Ladame, Dana Al Sulaiman
  • PEPTIDE NUCLEIC ACID FUNCTIONALIZED HYDROGEL MICRONEEDLES FOR SAMPLING AND DETECTION OF INTERSTITIAL FLUID NUCLEIC ACIDS
    Publication number: 20230242969
    Abstract: The present disclosure relates to a device, comprising a base and a plurality of microneedles attached to the base, wherein each microneedle has an outer surface; the outer surface of at least one microneedle being coated with a composition comprising at least one polymer and least one Peptide Nucleic Acid (PNA). The present disclosure additionally relates to a method of detecting an analyte in interstitial fluid (ISF), comprising contacting the device to a subject, for example, to human skin.
    Type: Application
    Filed: January 13, 2023
    Publication date: August 3, 2023
    Inventors: Darrell J. Irvine, Jason Y.H. Chang, Sylvain Ladame, Dana Al-Sulaiman
  • PEPTIDE NUCLEIC ACID FUNCTIONALIZED HYDROGEL MICRONEEDLES FOR SAMPLING AND DETECTION OF INTERSTITIAL FLUID NUCLEIC ACIDS
    Publication number: 20200377929
    Abstract: The present disclosure relates to a device, comprising a base and a plurality of microneedles attached to the base, wherein each microneedle has an outer surface; the outer surface of at least one microneedle being coated with a composition comprising at least one polymer and least one Peptide Nucleic Acid (PNA). The present disclosure additionally relates to a method of detecting an analyte in interstitial fluid (ISF), comprising contacting the device to a subject, for example, to human skin.
    Type: Application
    Filed: May 29, 2020
    Publication date: December 3, 2020
    Inventors: Darrell J. Irvine, Jason Y.H. Chang, Sylvain Ladame, Dana Al Sulaiman