Abstract: The invention generally relates to methods for manually calibrating imaging systems such as optical coherence tomography systems. In certain aspects, an imaging system displays an image showing a target and a reference item. A user looks at the image and indicates a point within the image near the reference item. A processer detects an actual location of the reference item within an area around the indicated point. The processer can use an expected location of the reference item with the detected actual location to calculate a calibration value and provide a calibrated image. In this way, a user can identify the actual location of the reference point and a processing algorithm can give precision to the actual location.

Abstract: A method of authorizing a limited use intravascular device can include determining if the intravascular device is in communication with a clinical system; determining if the intravascular device is authorized for clinical operation without providing the clinical system access to intravascular device data stored on the intravascular device; and providing an authorization signal to the clinical system. An intravascular device can include a flexible elongate member including a sensing component at a distal portion and a connector at a proximal portion, the connector including: a memory component configured to store a parameter value; a processing component; and a charge storage component configured to power the memory component and/or the processing component; wherein the processing component is configured to determine if the flexible elongate member is authorized for clinical operation using the parameter value without providing the parameter value to a clinical system.

Abstract: The invention generally relates to methods for manually calibrating imaging systems such as optical coherence tomography systems. In certain aspects, an imaging system displays an image showing a target and a reference item. A user looks at the image and indicates a point within the image near the reference item. A processer detects an actual location of the reference item within an area around the indicated point. The processer can use an expected location of the reference item with the detected actual location to calculate a calibration value and provide a calibrated image. In this way, a user can identify the actual location of the reference point and a processing algorithm can give precision to the actual location.

Abstract: A method of authorizing a limited use intravascular device can include determining if the intravascular device is in communication with a clinical system; determining if the intravascular device is authorized for clinical operation without providing the clinical system access to intravascular device data stored on the intravascular device; and providing an authorization signal to the clinical system. An intravascular device can include a flexible elongate member including a sensing component at a distal portion and a connector at a proximal portion, the connector including: a memory component configured to store a parameter value; a processing component; and a charge storage component configured to power the memory component and/or the processing component; wherein the processing component is configured to determine if the flexible elongate member is authorized for clinical operation using the parameter value without providing the parameter value to a clinical system.

Abstract: A method of authorizing a limited use intravascular device can include determining if the intravascular device is in communication with a clinical system; determining if the intravascular device is authorized for clinical operation without providing the clinical system access to intravascular device data stored on the intravascular device; and providing an authorization signal to the clinical system. An intravascular device can include a flexible elongate member including a sensing component at a distal portion and a connector at a proximal portion, the connector including: a memory component configured to store a parameter value; a processing component; and a charge storage component configured to power the memory component and/or the processing component; wherein the processing component is configured to determine if the flexible elongate member is authorized for clinical operation using the parameter value without providing the parameter value to a clinical system.

Abstract: A method of authorizing a limited use intravascular device can include determining if the intravascular device is in communication with a clinical system; determining if the intravascular device is authorized for clinical operation without providing the clinical system access to intravascular device data stored on the intravascular device; and providing an authorization signal to the clinical system. An intravascular device can include a flexible elongate member including a sensing component at a distal portion and a connector at a proximal portion, the connector including: a memory component configured to store a parameter value; a processing component; and a charge storage component configured to power the memory component and/or the processing component; wherein the processing component is configured to determine if the flexible elongate member is authorized for clinical operation using the parameter value without providing the parameter value to a clinical system.

Abstract: Imaging arrays comprising at least two different imaging pixel types are described. The different imaging pixel types may differ in their light sensitivities and/or light saturation levels. Methods of processing the output signals of the imaging arrays are also described, and may produce images having a greater dynamic range than would result from an imaging array comprising only one of the at least two different imaging pixel types.

Abstract: Imaging arrays comprising at least two different imaging pixel types are described. The different imaging pixel types may differ in their light sensitivities and/or light saturation levels. Methods of processing the output signals of the imaging arrays are also described, and may produce images having a greater dynamic range than would result from an imaging array comprising only one of the at least two different imaging pixel types.

Abstract: A method according to an embodiment of the invention includes receiving a first optical image from an endoscope having a plurality of imaging fibers. A spatial frequency is identified that is associated with the plurality of imaging fibers. A second optical image is received from the endoscope. The spatial frequency is filtered from the second optical image. A method according to another embodiment includes producing an optical image of at least a portion of a body lumen using a fiberscope. The optical image is transmitted to a video camera coupled to the fiberscope. A honeycomb pattern associated with a fiber bundle of the fiberscope is removed from the optical image. In some embodiments, the honeycomb pattern can be removed in substantially real time. In some embodiments, prior to producing the optical image, a calibration cap is coupled to the fiberscope and used in a calibration process.

Abstract: A system and method process non-linear image data, still or video, from a digital imager. Noise generated by analog-to-digital converters is filtered from a pixel of digital image data. Moreover, the effects of single pixel defects in the imager are eliminated by clamping a predetermined pixel of image data within the window when the value of the predetermined pixel is greater than a maximum value of the image data of neighboring pixels or less than a minimum value of the image data of neighboring pixels. Ripples in image data are reduced by eliminating the effects of single pixel defects before filtering for crosstalk caused by electrical crosstalk between sensor elements in an imager. Dark current is removed from image data generated by an imager by subtracting a fraction of a determined dark current value from all image data generated by the imager to compensate for nonlinearities in dark current across the imager.