Patents by Inventor Jasper SPRINGER

Jasper SPRINGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MACROCYCLES AS CFTR MODULATORS
    Publication number: 20240208992
    Abstract: The present invention relates to macrocyclic compounds of Formula (I) wherein Ar1, Ar2, R1, R2, R3, R4, and X are as described in the description, their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of Formula (I), and especially to their use as modulators of CFTR.
    Type: Application
    Filed: July 12, 2021
    Publication date: June 27, 2024
    Inventors: Martin BOLLI, Christine BROTSCHI, Malgorzata COMMANDEUR, John GATFIELD, Thierry KIMMERLIN, Hervé SIENDT, Jasper SPRINGER, Clemens WAGNER, Anita WEGERT, Jodi T. WILLIAMS
  • NOVEL 6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)
    Publication number: 20220363686
    Abstract: The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.
    Type: Application
    Filed: November 1, 2019
    Publication date: November 17, 2022
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Alastair DONALD, Andreas URBAN, Susanne BONSMANN, Jasper SPRINGER, Anita WEGERT
  • NOVEL INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITUS B VIRUS (HBV)
    Publication number: 20220306647
    Abstract: The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.
    Type: Application
    Filed: April 29, 2020
    Publication date: September 29, 2022
    Applicant: AICURIS GMBH & CO. KG
    Inventors: Susanne BONSMANN, Alastair DONALD, Andreas URBAN, Burkhard KLENKE, Jasper SPRINGER
  • NOVEL PHENYL AND PYRIDYL UREAS ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)
    Publication number: 20220227785
    Abstract: The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.
    Type: Application
    Filed: April 29, 2020
    Publication date: July 21, 2022
    Applicant: AICURIS GMBH & CO. KG
    Inventors: Susanne BONSMANN, Alastair DONALD, Burkhard KLENKE, Andreas URBAN, Jasper SPRINGER
  • NOVEL INDOLIZINE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)
    Publication number: 20220227789
    Abstract: The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.
    Type: Application
    Filed: April 29, 2020
    Publication date: July 21, 2022
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Susanne BONSMANN, Alastair DONALD, Andreas URBAN, Jasper SPRINGER, Elena DETTA
  • 6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)
    Publication number: 20220081444
    Abstract: The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.
    Type: Application
    Filed: November 1, 2019
    Publication date: March 17, 2022
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Alastair DONALD, Andreas URBAN, Susanne BONSMANN, Jasper SPRINGER, Anita WEGERT
  • Highly active amino-thiazole substituted indole-2-carboxamides active against the hepatitis B virus (HBV)
    Patent number: 11267825
    Abstract: The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: March 8, 2022
    Assignee: AICURIS GMBH & CO. KG
    Inventors: Alastair Donald, Andreas Urban, Susanne Bonsmann, Anita Wegert, Christiaan Gremmen, Jasper Springer
  • Highly active pyrazolo-piperidine substituted indole-2-carboxamides active against the hepatitis B virus (HBV)
    Patent number: 11236087
    Abstract: The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: February 1, 2022
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Alastair Donald, Andreas Urban, Susanne Bonsmann, Anita Wegert, Jasper Springer
  • NOVEL, HIGHLY ACTIVE PYRAZOLO-PIPERIDINE SUBSTITUTED INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)
    Publication number: 20210179608
    Abstract: The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.
    Type: Application
    Filed: November 2, 2018
    Publication date: June 17, 2021
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Alastair DONALD, Andreas URBAN, Susanne BONSMANN, Anita WEGERT, Jasper SPRINGER
  • NOVEL, HIGHLY ACTIVE AMINO-THIAZOLE SUBSTITUTED INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)
    Publication number: 20200354379
    Abstract: The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.
    Type: Application
    Filed: November 2, 2018
    Publication date: November 12, 2020
    Applicant: AICURIS GMBH & CO. KG
    Inventors: Alastair DONALD, Andreas URBAN, Susanne BONSMANN, Anita WEGERT, Christiaan GREMMEN, Jasper SPRINGER