Patents by Inventor Jasper Williams

Jasper Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS TARGETING TMPRSS4 AND SLC34A2
    Publication number: 20250297255
    Abstract: Provided herein are polypeptides, nucleic acids, and cells comprising antigen-binding domains that specifically bind to Solute Carrier Family 34 Member 2 (SLC34A2) or Transmembrane protease, serine 4 (TMPRSS4), and methods of use thereof. Also provided are polypeptides, systems, nucleic acids, and cells comprising priming receptors comprising an antigen-binding domain that specifically binds Solute Carrier Family 34 Member 2 (SLC34A2) and chimeric antigen receptors (CAR) comprising an antigen-binding domain that specifically binds to Transmembrane protease, serine 4 (TMPRSS4).
    Type: Application
    Filed: March 20, 2025
    Publication date: September 25, 2025
    Inventors: Jasper Williams, Michelle Nguyen, Rona Harari Steinfeld, Jianying Liu, Matthew Drever, Samuel A. Williams, Stephanie Elise Busch, Pallavur V. Sivakumar, Gabriela Hernandez-Hoyos, Brian Andrew Fox, Cédric Cleyrat, Christopher Mark Hill, Lore K. Florin, Nels B. Hamacher, Craig Darwin Ostrander, Sergio L. Lacayo
  • IMMUNE CELLS HAVING CO-EXPRESSED SHRNAS AND LOGIC GATE SYSTEMS
    Publication number: 20250250350
    Abstract: Provided herein are recombinant nucleic acids encoding chimeric priming receptors that bind ALPG/P, chimeric antigen receptors that bind MSLN, and shRNA that target FAS, PTPN2, and/or TOX. Also provided are systems of chimeric priming receptors that bind ALPG/P, chimeric antigen receptors that bind MSLN, and shRNA that target FAS, PTPN2, and/or TOX, cells expressing such proteins and shRNA, and methods of use thereof.
    Type: Application
    Filed: January 17, 2025
    Publication date: August 7, 2025
    Inventors: Jasper Williams, Michelle Nguyen, Anzhi Yao, Stephen Santoro, Aaron Cooper, John Gagnon, Adam Litterman, Omar Khan, Natalie Bezman, Katherine Harris, Harbani Kaur Malik Chaudhry, Nicole Allen
  • IMMUNE CELLS HAVING CO-EXPRESSED SHRNAS AND LOGIC GATE SYSTEMS
    Publication number: 20240309106
    Abstract: Provided herein are recombinant nucleic acids encoding chimeric priming receptors that bind ALPG/P, chimeric antigen receptors that bind MSLN, and shRNA that target FAS, PTPN2, and/or TOX. Also provided are systems of chimeric priming receptors that bind ALPG/P, chimeric antigen receptors that bind MSLN, and shRNA that target FAS, PTPN2, and/or TOX, cells expressing such proteins and shRNA, and methods of use thereof.
    Type: Application
    Filed: May 29, 2024
    Publication date: September 19, 2024
    Inventors: Jasper Williams, Michelle Nguyen, Anzhi Yao, Stephen Santoro, Aaron Cooper, John Gagnon, Adam Litterman, Omar Khan, Natalie Bezman, Katherine Harris, Harbani Kaur Malik Chaudhry, Nicole Allen
  • Immune cells having co-expressed shRNAS and logic gate systems
    Patent number: 12037407
    Abstract: Provided herein are recombinant nucleic acids encoding chimeric priming receptors that bind ALPG/P, chimeric antigen receptors that bind MSLN, and shRNA that target FAS, PTPN2, and/or TOX. Also provided are systems of chimeric priming receptors that bind ALPG/P, chimeric antigen receptors that bind MSLN, and shRNA that target FAS, PTPN2, and/or TOX, cells expressing such proteins and shRNA, and methods of use thereof.
    Type: Grant
    Filed: May 3, 2023
    Date of Patent: July 16, 2024
    Assignee: Arsenal Biosciences, Inc.
    Inventors: Jasper Williams, Michelle Nguyen, Anzhi Yao, Stephen Santoro, Aaron Cooper, John Gagnon, Adam Litterman, Omar Khan, Natalie Bezman, Katherine Harris, Harbani Kaur Malik Chaudhry, Nicole Allen
  • IMMUNE CELLS HAVING CO-EXPRESSED SHRNAS AND LOGIC GATE SYSTEMS
    Publication number: 20230340139
    Abstract: Provided herein are recombinant nucleic acids encoding chimeric priming receptors that bind ALPG/P, chimeric antigen receptors that bind MSLN, and shRNA that target FAS, PTPN2, and/or TOX. Also provided are systems of chimeric priming receptors that bind ALPG/P, chimeric antigen receptors that bind MSLN, and shRNA that target FAS, PTPN2, and/or TOX, cells expressing such proteins and shRNA, and methods of use thereof.
    Type: Application
    Filed: May 3, 2023
    Publication date: October 26, 2023
    Inventors: Jasper Williams, Michelle Nguyen, Anzhi Yao, Stephen Santoro, Aaron Cooper, John Gagnon, Adam Litterman, Omar Khan, Natalie Bezman, Katherine Harris, Harbani Kaur Malik Chaudhry, Nicole Allen
  • IMMUNE CELLS HAVING CO-EXPRESSED SHRNAS AND LOGIC GATE SYSTEMS
    Publication number: 20220235380
    Abstract: Provided herein are recombinant nucleic acids encoding chimeric priming receptors that bind ALPG/P, chimeric antigen receptors that bind MSLN, and shRNA that target FAS, PTPN2, and/or TOX. Also provided are systems of chimeric priming receptors that bind ALPG/P, chimeric antigen receptors that bind MSLN, and shRNA that target FAS, PTPN2, and/or TOX, cells expressing such proteins and shRNA, and methods of use thereof.
    Type: Application
    Filed: March 8, 2022
    Publication date: July 28, 2022
    Inventors: Jasper Williams, Michelle Nguyen, Anzhi Yao, Stephen Santoro, Aaron Cooper, John Gagnon, Adam Litterman, Omar Khan, Natalie Bezman