Abstract: The present invention relates provides pharmaceutical compositions comprising an amorphous carvedilol salt and one or more pharmaceutically acceptable excipients, wherein the amorphous carvedilol salt is formed in situ during the preparation of the pharmaceutical composition. The amorphous carvedilol salt is preferably an amorphous carvedilol phosphate salt. The pharmaceutical compositions can be prepared by providing one or more inert cores; contacting the core or cores with a solution or a dispersion comprising carvedilol, an acid component and optionally a binder, in a solvent; removing the solvent; and optionally coating the core or cores with an extended release composition. Preferred pharmaceutical compositions contain both immediate-release pellets and at least one population of extended-release pellet.

Abstract: Enhanced parent control may be provided. In various embodiments, a consumer device may receive a plurality of elementary streams. The consumer device may comprise a decoder capable of extracting and decoding content advisory information directly from the elementary streams. The decoded content advisory information may be compared to user-determined parental control settings. The plurality of elementary streams may then be filtered individually such that a portion less than the entirety of a program contained in the elementary streams is not presented or replaced.

Abstract: The present invention relates provides pharmaceutical compositions comprising an amorphous carvedilol salt and one or more pharmaceutically acceptable excipients, wherein the amorphous carvedilol salt is formed in situ during the preparation of the pharmaceutical composition. The amorphous carvedilol salt is preferably an amorphous carvedilol phosphate salt. The pharmaceutical compositions can be prepared by providing one or more inert cores; contacting the core or cores with a solution or a dispersion comprising carvedilol, an acid component and optionally a binder, in a solvent; removing the solvent; and optionally coating the core or cores with an extended release composition. Preferred pharmaceutical compositions contain both immediate-release pellets and at least one population of extended-release pellet.

Abstract: The onset of activity of a first analgesic/antipyretic composition containing an analgesic/antipyretic effective amount of acetaminophen, caffeine and, optionally, aspirin is shortened by incorporating in the first composition an onset of analgesic/antipyretic activity shortening amount of at least one alkaline agent whereby a second composition is produced. The second composition being bioequivalent to the first composition but having a shorter onset of analgesic/antipyretic activity than the first composition.

Abstract: Systems and methods for on-demand purchasing and distribution of products associated with a television program (“assets”) to consumers, such as music, telephone ringtones, videos, CDs, DVDs, coupons, and other products. An asset tag insertion system inserts an asset tag into a television signal; the asset tag identifies an asset associated with a television program represented by the television signal. A settop box program is responsive to an asset tag contained in a television signal for extracting the asset tag and displaying information corresponding to the asset tag to a viewer. The settop box program is further responsive to a command from the viewer for a purchase or other transaction involving the asset, for generating an order command corresponding to an order for the asset. The settop box program is further responsive to communicate the order command to an order management system, which delivers the asset to the purchaser.

Abstract: The invention concerns a composition containing a high level of Vitamin E in encapsulated form, preferably as beadlets or spray dried, and a high level of silicates. The composition is compressible into tablets or caplets that do not leach out Vitamin E into the tablet matrix during compression and/or storage. The composition preferably contains vitamins and minerals in doses optimized for cardiovascular health.

Abstract: A tablet core containing a water-soluble, preferably highly water-soluble, active ingredient is coated for sustained release with an aqueous-based coating of an ethyl acrylate-methyl methacrylate copolymer. The amount of copolymer applied, on a dry basis, being about 0.5% to about 2% by weight, based on the total weight of the coated tablet. The coated tablet is dried for not more than about 30 minutes, preferably for about 10 to about 15 minutes, at about 50° C. Notwithstanding the greatly shortened drying time and/or low percentage of copolymner applied, the coated tablet surprisingly exhibits a substantially stable dissolution profile. Tablets containing potassium chloride and coated in accordance with the invention surprisingly exhibit a dissolution profile comparable to that afforded by potassium chloride tablets coated for sustained release with an organic solvent-based coating.

Abstract: There is provided a coating composition that masks the undesirable taste of a pharmaceutically active ingredient, i.e. drug or medicine, that is taken orally. The coating composition is comprised of dimethylaminoethyl methacrylate and neutral methacrylic acid ester, a cellulose ester polymer, and an alkaline modifier.

Abstract: There is provided a coating composition that masks the undesirable taste of a pharmaceutically active ingredient, i.e. drug or medicine, that is consumed orally. The coating composition has polyvinyl acetate, and a dimethylaminoethyl methacrylate and neutral methacrylic acid ester. Optionally, an alkaline modifier may be included in the coating composition to enhance release of the active ingredient.

Abstract: There is provided a coating composition that masks the undesirable taste of a pharmaceutically active ingredient, i.e. drug or medicine, that is taken orally. The coating composition is comprised of dimethylaminoethyl methacrylate and neutral methacrylic acid ester, a cellulose ester polymer, and an alkaline modifier.

Abstract: The invention concerns a composition containing a high level of Vitamin E in encapsulated form, preferably as beadlets or spray dried, and a high level of silicates. The composition is compressible into tablets or caplets that do not leach out Vitamin E into the tablet matrix during compression and/or storage. The composition preferably contains vitamins and minerals in doses optimized for cardiovascular health.