Abstract: A plurality of electrophysiology (EP) data points, each including an electrogram signal, can be used to visualize cardiac activity. Each EP data point can be characterized as substrate or healthy, and a cloud map of the substrate EP data points can be generated. A graphical representation of the cloud map can be output in combination with a graphical representation of an electrophysiology map of the healthy EP data points. In alternative embodiments, the electrogram signals can be transformed into the wavelet domain, thereby computing a plurality of scalograms, and computing a wave function of each scalogram, thereby computing a plurality of wave functions. A propagation map, such as a propagation wave map and/or propagation wave trail map, can then be generated from the wave functions and output graphically.

Abstract: An electroanatomical mapping system graphically represents local activation time (LAT) information contained in data set including a plurality of electrophysiology (EP) data points. The system computes a spatial gradient over a spatial kernel centered at an EP data point and a plurality of temporal gradients for the EP data points set. Using the gradients, the electroanatomical mapping system can detect spatial outlier EP data points and temporal outlier EP data points. These outlier EP data points can then be corrected prior to outputting a graphical representation of the LAT map on a model of a cardiac surface.

Abstract: The present disclosure provides systems and methods for generating a local activation time (LAT) map. A method includes receiving at least one reference electrogram, receiving at least one roving electrogram, detecting cardiac activations in the at least one reference electrogram, detecting roving cardiac activations in the at least one roving electrogram, identifying, at a trigger time, a most recent reference cardiac activation of the detected reference cardiac activations, identifying, a corresponding roving cardiac activation of the detected roving cardiac activations that is closest in time to the most recent reference cardiac activation, the corresponding roving cardiac activation identified independent of any roving activation interval (RAI), computing, a LAT as a time difference between the most recent reference cardiac activation and the corresponding roving cardiac activation, and generating and displaying, a LAT map based on the computed LAT.

Abstract: Pulmonary vein isolation has become a first-line treatment for symptomatic drug refractory atrial fibrillation (AF). In the context of PVI procedures, linear ablation lesions are delivered in order to achieve PV isolation. Electrophysiological maps from data collected by high density (HD) grid catheters can be used to identify conduction gaps associated within circumferential pulmonary vein isolation lesions.

Abstract: The present disclosure provides apparatuses and methods for navigating a medical device into the body of a patient during an intracoronary or other medical procedure. In many embodiments, the present disclosure includes the use of a guidewire managing assembly that may be used in combination with a guidewire that includes a medical positioning system sensor. This guidewire managing assembly and sensor enabled guidewire are used in combination with a medical positioning system to determine the position of a medical device, such as a catheter or catheter sheath, and specifically the tip of the catheter or catheter sheath, that is threaded over the guidewire during a procedure. The present disclosure further relates to methods of tracking a medical device, such as a catheter tip, inside the body of a subject during a procedure.

Abstract: The present disclosure provides apparatuses and methods for navigating a medical device into the body of a patient during an intracoronary or other medical procedure. In many embodiments, the present disclosure includes the use of a guidewire managing assembly that may be used in combination with a guidewire that includes a medical positioning system sensor. This guidewire managing assembly and sensor enabled guidewire are used in combination with a medical positioning system to determine the position of a medical device, such as a catheter or catheter sheath, and specifically the tip of the catheter or catheter sheath, that is threaded over the guidewire during a procedure. The present disclosure further relates to methods of tracking a medical device, such as a catheter tip, inside the body of a subject during a procedure.