Patents by Inventor Jaume Piulats

Jaume Piulats has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification of n-alkylglycine trimers for induction of apoptosis
    Publication number: 20060229255
    Abstract: N-alkylglycine trimers with the capacity to arrest the cell cycle in human cancer cells and to induce apoptosis useful for the therapy of cancer. Combination of said N-alkylglycine trimers with taxol.
    Type: Application
    Filed: April 8, 2004
    Publication date: October 12, 2006
    Inventors: Gema Tarrason, Claudia Cases, Jaume Piulats, Angel Messeguer, Nuria Cortes, Isabel Masip
  • Genetic analysis of biological samples in arrayed expanded representations of their nucleic acids
    Publication number: 20040241696
    Abstract: The invention provides a method for the genetic analysis of biological samples after generation and expansion of subsets representing their nucleic acids. Each subset contains a characteristic but arbitrarily selected representation. Different subsets display complementary representations. The method is specially suitable for the study of gene expression profiles.
    Type: Application
    Filed: March 8, 2004
    Publication date: December 2, 2004
    Inventors: Miguel A Peinado, Rosa-Ana Risques, Elisenda Vendrell, Gabriel Capella, Monica Grau, Antonia Obrador, Gemma Tarafa, Victor Moreno, Xavier Sole, Elisabet Rosell-Vives, Marta Soler, Marc Masa Alvarez, Jaume Piulats
  • Mfq-111, a novel human gtpase like protein
    Publication number: 20040137595
    Abstract: MFQ-111 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing MFQ-111 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: February 19, 2003
    Publication date: July 15, 2004
    Inventors: Marc Masa Alvarez, Blanca Rodes Gubern, Ramon Messeguer Peypoch, Elisabet Rosell Vives, Jaume Piulats Xanco
  • Polynucleotides and polypeptides encoded thereby
    Publication number: 20040073004
    Abstract: MFQ-114 polypeptides and polynucleotides and metnods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing MFQ-114 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: April 18, 2003
    Publication date: April 15, 2004
    Inventors: Marta Soler Riera, Marc Masa Alvarez, Jose Luis Hernandez Miguez, Jaume Piulats Xanco, Elisabet Rosell Vives
  • Anti-.alpha.V-integrin monoclonal antibody
    Patent number: 5985278
    Abstract: The invention relates to a novel monoclonal antibody, a hybridoma cell line producing said antibody, DNA sequences coding for said antibody, and amino acid sequences. The monoclonal antibody, a preferred embodiment of which is named 17E6, has the following properties:reacting only with the .alpha.V-chain of human .alpha.V-integrins,blocking the attachment to the integrin substrate of the .alpha.V-integrin bearing cell,triggering reversal of established cell matrix interaction caused by .alpha.V-integrins,blocking tumor development, andshowing no cytotoxic activity.
    Type: Grant
    Filed: December 19, 1995
    Date of Patent: November 16, 1999
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Francesc Mitjans, Jaume Piulats, Elisabet Rosell, Jaume Adan, Simon Goodman, Diane Hahn
  • Anti-idiotypic antibodies which induce an immune response against epidermal growth factor receptor
    Patent number: 5969107
    Abstract: The present invention relates to anti-idiotypic antibodies which induce an immune response against tumors, bearing as antigen the epidermal growth factor receptor (EGFR). The antibodies of the invention may mimic said antigen. As preferred embodiment the antibodies of the invention derive from mAB 425 (ATCC HB 9629) or a humanized or chimeric derivative thereof.
    Type: Grant
    Filed: May 24, 1996
    Date of Patent: October 19, 1999
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Ana Carceller, Elisabet Rosell, Alicia Gomez, Jaume Adan, Jaume Piulats
  • Anti-EGFR single-chain Fvs and anti-EGFR antibodies
    Patent number: 5844093
    Abstract: This invention relates to new anti-EGFR antibodies and single-chain Fvs (scFvs) thereof which can be obtained from phage-antibody libraries constructed from cells of an immunized mammalian, preferably a mouse. Two of the single-chain Fvs isolated from the phage-antibody libraries were engineered to create partially humanized whole antibody molecules. These chimeric anti-EGFR antibodies contain constant regions of human immunoglobulins, and can be used as well as the single-chain Fvs as agents for the diagnosis and therapy of human tumors.
    Type: Grant
    Filed: November 17, 1995
    Date of Patent: December 1, 1998
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: A. Cathrine Kettleborough, Mary M. Bendig, Keith H. Ansell, Detlef Gussow, Jaume Adan, Francesc Mitjans, Elisabet Rosell, Francesc Blasco, Jaume Piulats