Patents by Inventor Javier Agejas-Chicharro

Javier Agejas-Chicharro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzyl sulfonamide compounds useful as MoGAT-2 inhibitors
    Patent number: 9416138
    Abstract: The present invention provides compounds of Formula I. Wherein R1, L, and A are as described herein, or a pharmaceutical salt thereof, processes for preparing the compounds, and methods of treating a condition, such as hypertriglyceridemia, using the compounds.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: August 16, 2016
    Assignee: Eli Lilly and Company
    Inventors: Francisco Javier Agejas-Chicharro, Nuria Diaz Buezo, Joseph Michael Gruber, Douglas Richard Stack
  • NOVEL BENZYL SULFONAMIDE COMPOUNDS USEFUL AS MOGAT-2 INHIBITORS
    Publication number: 20150284404
    Abstract: The present invention provides compounds of Formula I. Wherein R1, L, and A are as described herein, or a pharmaceutical salt thereof, processes for preparing the compounds, and methods of treating a condition, such as hypertriglyceridemia, using the compounds.
    Type: Application
    Filed: October 30, 2013
    Publication date: October 8, 2015
    Inventors: Francisco Javier Agejas-Chicharro, Nuria Diaz Buezo, Joseph Michael Gruber, Douglas Richard Stack
  • Compounds and methods for modulating FXR
    Patent number: 8153624
    Abstract: Compounds of formula (I): formula (I) wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and diseases related to dyslipidemia.
    Type: Grant
    Filed: July 11, 2008
    Date of Patent: April 10, 2012
    Assignee: Eli Lilly and Company
    Inventors: Michael James Genin, Francisco Javier Agejas-Chicharro, Ana Belen Bueno Melendo, Peter Rudolph Manninen, Alan M. Warshawsky
  • Cyclopropyl compounds
    Patent number: 8063079
    Abstract: A compound of the formula: and pharmaceutical compositions for the treatment of diabetes.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: November 22, 2011
    Assignee: Eli Lilly and Company
    Inventors: Ana Belen Bueno Melendo, Francisco Javier Agejas-Chicharro
  • Pyridyl derivatives and their use as mGlu5 antagonists
    Patent number: 7915424
    Abstract: The present invention is directed toward pyridyl derivatives of formula (I) as antagonists of the mGlu5 receptor.
    Type: Grant
    Filed: March 9, 2005
    Date of Patent: March 29, 2011
    Assignee: Eli Lilly and Company
    Inventors: Francisco Javier Agejas-Chicharro, Bruce Anthony Dressman, Jose Antonio Martinez Perez, James Allen Monn, Mohammad Sadegh Zia-Ebrahimi, Sonia Gutierrez Sanfeliciano, Steven Marc Massey, Steven Scott Henry
  • Compounds and methods for modulating FX-receptors
    Patent number: 7863302
    Abstract: Compounds of formula and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.
    Type: Grant
    Filed: February 2, 2007
    Date of Patent: January 4, 2011
    Assignee: Eli Lilly and Company
    Inventors: Michael Gregory Bell, Michael James Genin, Peter Ambrose Lander, Lindsay Scott Stelzer, Robert Anthony Doti, Francisco Javier Agejas-Chicharro, Ana Belen Bueno Melendo, Peter Rudolph Manninen, Jason Matthew Ochoada, Quanrong Shen, Alan M. Warshawsky, Tianwei Ma, Ryan Edward Stites
  • CYCLOPROPYL COMPOUNDS
    Publication number: 20100160395
    Abstract: A compound of the formula: and pharmaceutical compositions for the treatment of diabetes.
    Type: Application
    Filed: December 11, 2009
    Publication date: June 24, 2010
    Inventors: Ana Belen Bueno Melendo, Francisco Javier Agejas-Chicharro
  • COMPOUNDS AND METHODS FOR MODULATING FXR
    Publication number: 20100152166
    Abstract: Compounds of formula (I): formula (I) wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and diseases related to dyslipidemia.
    Type: Application
    Filed: July 11, 2008
    Publication date: June 17, 2010
    Applicant: ELI LILLY AND COMPANY
    Inventors: Michael James Genin, Francisco Javier Agejas-Chicharro, Ana Belen Bueno Melendo, Peter Rudolph Manninen, Alan M. Warshawsky
  • Morpholine derivatives as norepinephrine reuptake inhibitors
    Patent number: 7595315
    Abstract: Compounds of the general formula (I) are inhibitors of the reuptake of norepinephrine. As such, they may be useful for the treatment of disorders of the central and/or peripheral nervous system.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: September 29, 2009
    Assignee: Eli Lilly and Company
    Inventors: Peter Thaddeus Gallagher, Carlos Lamas-Peteira, Francisco Javier Agejas-Chicharro
  • Compounds and Methods for Modulating Fx-Receptors
    Publication number: 20080306125
    Abstract: Compounds of formula. wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.
    Type: Application
    Filed: February 2, 2007
    Publication date: December 11, 2008
    Inventors: Michael Gregory Bell, Michael James Genin, Peter Ambrose Lander, Lindsay Scott Stelzer, Robert Anthony Doti, Francisco Javier Agejas-Chicharro, Ana Belen Bueno Melendo, Peter Rudolph Manninen, Jason Matthew Ochoada, Quanrong Shen, Alan M. Warshawsky, Tianwei Ma, Ryan Edward Stites
  • Pyridyl Derivatives and Their Use as Mglu5 Antagonists
    Publication number: 20080194647
    Abstract: The present invention is directed toward pyridyl derivatives of formula (I) as antagonists of the mGlu5 receptor.
    Type: Application
    Filed: March 9, 2005
    Publication date: August 14, 2008
    Applicant: ELI LILLY AND COMPANY
    Inventors: Francisco Javier Agejas-Chicharro, Anthony Bruce Dressman, Sonia Gutierrez Sanfeliciano, Steven Scott Henry, Jose Antonio Martinez Perez, Steven Marc Massey, James Allen Monn, Mohammad Sadegh Zia-Ebrahimi
  • Isochroman compounds for treatment of CNS disorders
    Patent number: 7335660
    Abstract: This invention relates to compounds of formula (I) where R1 to R12, —W—V—, —X—Y—, p and n have the values defined in claim 1, their preparation and use as pharmaceuticals for the treatment of central nervous system disorders, such as depression, bipolar disorder, and anxiety.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: February 26, 2008
    Assignee: Eli Lilly and Company
    Inventors: Javier Agejas-Chicharro, Graham Henry Timms, Andrew Caerwyn Williams, Nicholas Paul Camp, Jeremy Gilmore, Ana Belen Bueno Melendo, Carlos Lamas-Peteira
  • Isochroman compounds for treatment of cns disorders
    Publication number: 20050014750
    Abstract: This invention relates to compounds of formula (I) where R1 to R12, —W—V—, —X—Y—, p and n have the values defined in claim 1, their preparation and use as pharmaceuticals.
    Type: Application
    Filed: December 6, 2002
    Publication date: January 20, 2005
    Inventors: Javier Agejas-Chicharro, Graham Timms, Andrew Williams, Nicholas Camp, Jeremy Gilmore, Ana Bueno Melendo, Carlos Lamas-Peteira
  • Pharmaceutical compounds
    Publication number: 20040122001
    Abstract: This invention relates to compounds of formula (I) where R1 to R12, —W—V—, —X—Y—, m and n have the values defined in claim 1, their preparation and use as pharmaceuticals.
    Type: Application
    Filed: January 16, 2004
    Publication date: June 24, 2004
    Inventors: Javier Agejas-Chicharro, Ana Belen Bueno Melendo, Nicholas Paul Camp, Jeremy Gilmore, Alma Maria Jimenez-Aguado, Carlos Lamas-Peteira, Alicia Marcos-Llorente, Michael Philip Mazanetz, Carlos Montero Salgado, Graham Henry Timms, Andrew Caerwyn Williams