Patents by Inventor Javier Bartroli Orpi

Javier Bartroli Orpi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline antifungal compounds
    Patent number: 8258296
    Abstract: The present subject matter relates to novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one represented by Formula II: , pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms. In particular, the present subject matter relates to the specific crystalline Forms I, II, III, IV V, and VI of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: September 4, 2012
    Assignee: Palau Pharma, S.A.
    Inventors: Antonio Cánovas Paredes, Javier Bartroli Orpi, Elies Molins Grau, Anna Roig Serra, Kevin Meyer, Keith Lorimer
  • CRYSTALLINE ANTIFUNGAL COMPOUNDS
    Publication number: 20110092702
    Abstract: Novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one, pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms. In particular, the present subject matter relates to the specific crystalline Forms I, II, III, IV, V, and VI of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one.
    Type: Application
    Filed: December 16, 2010
    Publication date: April 21, 2011
    Applicants: PALAU PHARMA, S.A., STIEFEL LABORATORIES, INC.
    Inventors: Antonio Cánovas PAREDES, Javier Bartroli ORPI, Elies Molins GRAU, Anna Roig SERRA, Kevin MEYER, Keith LORIMER
  • Crystalline antifungal compounds
    Patent number: 7879867
    Abstract: Novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2 -hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one, pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: February 1, 2011
    Assignees: Palau Pharma, S.A., Stiefel Laboratories, Inc.
    Inventors: Antonio Cánovas Paredes, Javier Bartroli Orpi, Elies Molins Grau, Anna Roig Serra, Kevin Meyer, Keith Lorimer
  • 2,4-dihydroxybenzoic acid derivatives
    Patent number: 7589125
    Abstract: The present invention relates to novel compounds of formula (I) and to the salts, solvates and prodrugs thereof, wherein the meanings of the various substituents are as disclosed in the description. Said compounds are useful for the treatment or prevention of psoriasis and other immune diseases.
    Type: Grant
    Filed: July 17, 2003
    Date of Patent: September 15, 2009
    Assignee: Palau Pharma, S.A.
    Inventors: Javier Bartrolí Orpí, Carmen Almansa Rosales, Alberto Fernández De Arriba
  • Phosphoramide derivatives
    Patent number: 7550497
    Abstract: New phosphoramide derivatives of formula (I) and the salts and solvates thereof, wherein the meanings of the various substituents are as disclosed in the description. Said compounds are useful as antiinflammatory and analgesic agents.
    Type: Grant
    Filed: December 23, 2003
    Date of Patent: June 23, 2009
    Assignee: Palau Pharma, S.A.
    Inventors: Carmen Almansa Rosales, Javier Bartroli Orpi
  • Method for preparing pyrimidone derivatives with antifungal activity
    Patent number: 6653475
    Abstract: Process for the preparation of pyrimidone derivatives of formula I, which comprises reacting a compound of formula II with a compound of formula III in the presence of a base. The pyrimidone derivatives of formula I are useful as antifungal agents.
    Type: Grant
    Filed: September 9, 2002
    Date of Patent: November 25, 2003
    Assignee: J. Uriach & Cia, S.A.
    Inventors: Javier Bartroli Orpi, Manuel Anguita Lopez
  • Method for preparing pyrimidone derivatives with antifungal activity
    Publication number: 20030064986
    Abstract: Process for the preparation of pyrimidone derivatives of formula I, which comprises reacting a compound of formula II with a compound of formula III in the presence of a base. The pyrimidone derivatives of formula I are useful as antifungal agents.
    Type: Application
    Filed: September 9, 2002
    Publication date: April 3, 2003
    Inventors: Javier Bartroli Orpi, Manuel Anguita Lopez