Abstract: The present invention relates to a disposable device for performing a plurality of identical and simultaneous microfluidic experiments according to a set of consecutive steps. Another object of the invention is the machine which is adapted to act on the disposable device, allowing performance of the plurality of experiments. The particular configuration of the disposable device allows that different experiments require redesigning only one of the portions of the device, maintaining the remaining components without necessarily being modified.

Abstract: The present invention relates to an apparatus for determining the temperature of microfluidic devices and is comprised in the field of heating and cooling systems for reaction chambers in microfluidic devices where thermal cycling processes or reactions are performed at constant temperature.

Abstract: The present invention is a multiplexed valve for microfluidic devices suitable for establishing the fluidic communication or the cut-off of said fluidic communication between a microfluidic inlet and a plurality of microfluidic outlets, or a plurality of microfluidic inlets and a microfluidic outlet, or a plurality of microfluidic inlets and a plurality of microfluidic outlets. The structure of this multiplexed valve is characterized by a preferably stratified structure formed by a support base, an elastically deformable membrane and a rigid movable part. This rigid movable part allows a set of positions giving rise to the combinations of conditions for the selective opening or closing of the fluidic communications between the inlets and the outlets.

Abstract: An SU-8 microneedle for monitoring and stimulating neurons, has a thickness less than 100 micrometers and a length of 50 micrometers to 10 centimeters. A manufacturing method allows removing the microneedle from the substrate without using mechanical devices due to the initial coating of a rigid substrate with an aluminium layer as a sacrificial layer and the final chemical etching of the aluminium layer for chemically removing the microneedle obtained in known intermediate photolithographic manufacturing steps.

Abstract: The present invention relates to a micro-device for selective and non-invasive separation of particles in polydispersed suspensions through the strategic use of ultrasounds, laminar flow and standing wave effects in a channel produced in a chip by means of microtechnology. Said device is a resonant multi-layer system with a modified lambda quarter-type treatment channel, which enables the particles to be channeled and separated in a flow inside the substrate channel without touching the walls of the device, in order to avoid problems of adherence. Said micro-device can be used in the field of biomedicine and/or biotechnology for the separation and concentration of cells, preferably human cells, applicable to research and medical processes for diagnosis and treatment.

Abstract: The present invention relates to a method and a portable device to detect a genetic material in a biological sample using the technique known as PCR (Polymerase Chain Reaction). The device comprises a reaction chamber which incorporates means of heating arranged to heat said chamber. The detection method is characterized in that the main phases are performed in the reaction chamber. The miniaturized system has the object of increasing efficiency, simplicity of use and the portability of the PCR in comparison with laboratory scale analysis.