Abstract: Machine learning adversarial campaign mitigation on a computing device. The method may include deploying an original machine learning model in a model environment associated with a client device; deploying a classification monitor in the model environment to monitor classification decision outputs in the machine learning model; detecting, by the classification monitor, a campaign of adversarial classification decision outputs in the machine learning model; applying a transformation function to the machine learning model in the model environment to transform the adversarial classification decision outputs to thwart the campaign of adversarial classification decision outputs; determining a malicious attack on the client device based in part on detecting the campaign of adversarial classification decision outputs; and implementing a security action to protect the computing device against the malicious attack.

Abstract: The disclosed computer-implemented method for adaptively managing data drift in a classifier may include (i) receiving, at a computing device, an input sample of digital information having an unknown reputation and (ii) performing a security action that may include (A) identifying the input sample as benign or malicious based on a result obtained by classifying the input sample using a machine learning model trained using activity regularization, (B) calculating an internal activity of the machine learning model occurring during the classifying, (C) calculating an activation entropy of the machine learning model occurring during the classifying, (D) comparing a combination of the internal activity and the activation entropy to a threshold, and (E) when the combination of the internal activity and the activation entropy meets or exceeds the threshold, identifying the result as a low-confidence result. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The disclosed computer-implemented method for trichotomous malware classification may include (1) identifying a sample potentially representing malware, (2) selecting a machine learning model trained on a set of samples to distinguish between malware samples and benign samples, (3) analyzing the sample using a plurality of stochastically altered versions of the machine learning model to produce a plurality of classification results, (4) calculating a variance of the plurality of classification results, and (5) classifying the sample based at least in part on the variance of the plurality of classification results. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: Principles from the analogous field of cardiac electrophysiology are translated to neuro electrophysiology whereby electrically competent catheters and introducing devices are threaded intravascularly through large vessel access (e.g., leg or arm) into the arterial or more typically the venous system to or within the brain tissue, possibly targeting a specific region that needs to be functionally mapped. After passive recording and mapping of important activity exactly to a 3-dimensional, high resolution brain image taken either before or during the procedure, electrical stimulation paradigms are triggered to both evoke responses to help map regions vital to the epileptic network or pathologically functioning networks in other neurological and/or psychiatric conditions, and then to map brain function in specific regions during motor, sensory, emotional, psychiatric and cognitive testing, in order to localize these functions in relation to the epileptic network.

Abstract: A method and an apparatus for predicting and detecting epileptic seizure onsets within a unified multiresolution probabilistic framework, enabling a portion of the device to automatically deliver a progression of multiple therapies, ranging from benign to aggressive as the probabilities of seizure warrant. Based on novel computational intelligence algorithms, a realistic posterior probability function P(ST|x) representing the probability of one or more seizures starting within the next T minutes, given observations x derived from IEEG or other signals, is periodically synthesized for a plurality of prediction time horizons. When coupled with optimally determined thresholds for alarm or therapy activation, probabilities defined in this manner provide anticipatory time-localization of events in a synergistic logarithmic-like array of time resolutions, thus effectively circumventing the performance vs. prediction-horizon tradeoff of single-resolution systems.

Abstract: A method and an apparatus for predicting and detecting epileptic seizure onsets within a unified multiresolution probabilistic framework, enabling a portion of the device to automatically deliver a progression of multiple therapies, ranging from benign to aggressive as the probabilities of seizure warrant. Based on novel computational intelligence algorithms, a realistic posterior probability function P(ST|x) representing the probability of one or more seizures starting within the next T minutes, given observations x derived from IEEG or other signals, is periodically synthesized for a plurality of prediction time horizons. When coupled with optimally determined thresholds for alarm or therapy activation, probabilities defined in this manner provide anticipatory time-localization of events in a synergistic logarithmic-like array of time resolutions, thus effectively circumventing the performance vs. prediction-horizon tradeoff of single-resolution systems.

Abstract: An adaptive method and apparatus for forecasting and controlling neurological abnormalities in humans such as seizures or other brain disturbances. The system is based on a multi-level control strategy. Using as inputs one or more types of physiological measures such as brain electrical, chemical or magnetic activity, heart rate, pupil dilation, eye movement, temperature, chemical concentration of certain substances, a feature set is selected off-line from a pre-programmed feature library contained in a high level controller within a supervisory control architecture. This high level controller stores the feature library within a notebook or external PC. The supervisory control also contains a knowledge base that is continuously updated at discrete steps with the feedback information coming from an implantable device where the selected feature set (feature vector) is implemented.

Abstract: Developing a measure of critical systems-like behavior in an epilepsy patient in order to map epileptic networks, either passively or evoking responses through subthreshold stimulation, and to apply “therapeutic” stimulations to the patient that cause smaller, but more frequent dissipations of “energy,” a transcription product, subclinical electrophysiological activity or seizures in order to raise the clinical seizure initiation threshold, through releasing accumulated interictal energy in a seizure onset zone or elsewhere in the epileptic network, thereby preventing occurrence of larger more debilitating seizures.

Abstract: An epileptiform activity patient-specific template creation system permits a user to efficiently develop an optimized set of patient-specific parameters for epileptiform activity detection algorithms. The epileptiform activity patient template creation system is primarily directed for use with an implantable neurostimulator system having EEG storage capability, in conjunction with a computer software program operating within a computer workstation having a processor, disk storage and input/output facilities for storing, processing and displaying patient EEG signals. The implantable neurostimulator is operative to store records of EEG data when neurological events are detected, when it receives external commands to record, or at preset or arbitrary times. The computer workstation operates on stored and uploaded records of EEG data to derive the patient-specific templates via a single local minimum variant of a multidimensional greedy line search process and a feature overlay process.

Abstract: An epileptiform activity patient-specific template creation system permits a user to efficiently develop an optimized set of patient-specific parameters for epileptiform activity detection algorithms. The epileptiform activity patient template creation system is primarily directed for use with an implantable neurostimulator system having EEG storage capability, in conjunction with a computer software program operating within a computer workstation having a processor, disk storage and input/output facilities for storing, processing and displaying patient EEG signals. The implantable neurostimulator is operative to store records of EEG data when neurological events are detected, when it receives external commands to record, or at preset or random times. The computer workstation operates on stored and uploaded records of EEG data to derive the patient-specific templates.

Abstract: This invention is a method, and system for predicting the onset of a seizure prior to electrograph onset in an individual. During an “off-line” mode, signals representing brain activity of an individual (either stored or real time) are collected, and features are extracted from those signals. A subset of features, which comprise a feature vector, are selected by a predetermined process to most efficiently predict (and detect) a seizure in that individual. An intelligent prediction subsystem is also trained “off-line” based on the feature vector derived from those signals. During “on-line” operation, features are continuously extracted from real time brain activity signals to form a feacture vector, and the feature vector is continuously analyzed with the intelligent prediction subsystem to predict seizure onset in a patient.

Abstract: A method and apparatus is provided which analyzes an image of an object to detect and identify defects in the object utilizing multi-dimensional wavelet neural networks. “The present invention generates a signal representing part of the object, then extracts certain features of the signal. These features are then provided to a multidimensional neural network for classification, which indicates if the features correlate with a predetermined pattern. This process of analyzing the features to detect and identify predetermined patterns results in a robust fault detection and identification system which is computationally efficient and economical because of the learning element contained therein which lessens the need for human assistance.

Abstract: An epileptiform activity patient-specific template creation system permits a user to efficiently develop an optimized set of patient-specific parameters for epileptiform activity detection algorithms. The epileptiform activity patient template creation system is primarily directed for use with an implantable neurostimulator system having EEG storage capability, in conjunction with a computer software program operating within a computer workstation having a processor, disk storage and input/output facilities for storing, processing and displaying patient EEG signals. The implantable neurostimulator is operative to store records of EEG data when neurological events are detected, when it receives external commands to record, or at preset or arbitrary times. The computer workstation operates on stored and uploaded records of EEG data to derive the patient-specific templates via a single local minimum variant of a multidimensional greedy line search process and a feature overlay process.

Abstract: An epileptiform activity patient-specific template creation system permits a user to efficiently develop an optimized set of patient-specific parameters for epileptiform activity detection algorithms. The epileptiform activity patient template creation system is primarily directed for use with an implantable neurostimulator system having EEG storage capability, in conjunction with a computer software program operating within a computer workstation having a processor, disk storage and input/output facilities for storing, processing and displaying patient EEG signals. The implantable neurostimulator is operative to store records of EEG data when neurological events are detected, when it receives external commands to record, or at preset or random times. The computer workstation operates on stored and uploaded records of EEG data to derive the patient-specific templates.

Abstract: A method and apparatus is provided which analyzes an image of an object to detect and identify defects in the object utilizing multi-dimensional wavelet neural networks.