Abstract: The present invention relates to activated and ground sodium hexametaphosphate frit particles and antimicrobial composite material comprising said activated and ground sodium hexametaphosphate frit particles embedded in a thermoplastic polymer such as low density polyethylene (LDPE). The invention also relates to the method for obtaining the composite material of the invention and a thermal activation method for the thermal activation of a sodium hexametaphosphate salt in order to generate the activated and ground sodium hexametaphosphate frit particles. The antimicrobial material of the invention is preferably used in the food industry.

Abstract: The invention provides methods for treating cancer cells overexpressing Her-2/neu, the product of the erbB-2 gene, comprising administering a therapeutically effective amount of an unsaturated fatty acid. The cancer cells amenable to treatment exhibit relatively elevated activity levels of fatty acid synthase. Exemplary fatty acids useful in the methods of the invention include ?-9 monounsaturated fatty acids (e.g., oleic acid), ?-6 polyunsaturated fatty acids (e.g., ?-linolenic acid) and ?-3 polyunsaturated fatty acids (e.g., ?-linolenic acid). The invention also provides methods of preventing cancer comprising administering a prophylactically effective amount of a fatty acid and kits for preventing and/or treating cancer comprising a fatty acid and a conventional anti-cancer therapeutic.

Abstract: This invention relates to the field of recombinant DNA technology. The present invention relates to the isolation of a new DNA regulatory region, able to lead the expression of heterologous proteins in Pichia pastoris.