Patents by Inventor Javier PORTILLO

Javier PORTILLO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for irradiating mammalian cells with electron beams and/or X-rays
    Patent number: 11802271
    Abstract: The present invention relates to a method for irradiating a population of mammalian cells comprising at least one target mammalian cell with electron beams and/or X-rays, characterized in that: (i) a composition comprising a population of mammalian cells is irradiated in vitro with electron beams and/or X-rays, the population of mammalian cells containing at least one target mammalian cell and the dose rate being within the range from 5 Gy/sec to 107 Gy/sec, and (ii) optionally viable target mammalian cells are isolated or enriched from the population of mammalian cells, and to agents obtainable thereby and to uses thereof.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: October 31, 2023
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: Frank-Holm Rögner, Sebastian Ulbert, Jana Burkhardt, Javier Portillo, Jessy Schönfelder
  • Inactivation of pathogens in biological media
    Patent number: 11224669
    Abstract: The invention relates to the processing of fluid biological media, especially of culture media or cell- or virus suspensions, potentially containing active pathogens, with the aim of inactivating these pathogens and/or modifying ingredients in these biological media by thermal or radiological treatment.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: January 18, 2022
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: Martin Thoma, Klaus Fischer, Javier Portillo
  • Method for irradiating a liquid with accelerated electrons
    Patent number: 10980903
    Abstract: Methods and Apparatus are provided for irradiating a liquid with accelerated electrons. The liquid is prepared. The liquid is mixed with particles having at least one luminescent substance, where the particles are formed such that the particles are dispersed in the liquid after mixing. The liquid is irradiated with an electromagnetic radiation, which induces the at least one luminescent substance to luminesce. An actual value of a physical quantity characterizing the luminescence of the luminescent substance is detected. The liquid is irradiated with accelerated electrons until the detected actual value corresponds to a target value.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: April 20, 2021
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: Jessy Schönfelder, Frank-Holm Rögner, Javier Portillo Casado, Jörg Kubusch
  • METHOD FOR IRRADIATING MAMMALIAN CELLS WITH ELECTRON BEAMS AND/OR X-RAYS
    Publication number: 20200102539
    Abstract: The present invention relates to a method for irradiating a population of mammalian cells comprising at least one target mammalian cell with electron beams and/or X-rays, characterized in that: (i) a composition comprising a population of mammalian cells is irradiated in vitro with electron beams and/or X-rays, the population of mammalian cells containing at least one target mammalian cell and the dose rate being within the range from 5 Gy/sec to 107 Gy/sec, and (ii) optionally viable target mammalian cells are isolated or enriched from the population of mammalian cells, and to agents obtainable thereby and to uses thereof.
    Type: Application
    Filed: March 14, 2018
    Publication date: April 2, 2020
    Applicant: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: FRANK-HOLM RÖGNER, SEBASTIAN ULBERT, JANA BURKHARDT, JAVIER PORTILLO, JESSY SCHÖNFELDER
  • INACTIVATION OF PATHOGENS IN BIOLOGICAL MEDIA
    Publication number: 20190192704
    Abstract: The invention relates to the processing of fluid biological media, especially of culture media or cell- or virus suspensions, potentially containing active pathogens, with the aim of inactivating these pathogens and/or modifying ingredients in these biological media by thermal or radiological treatment.
    Type: Application
    Filed: August 31, 2017
    Publication date: June 27, 2019
    Applicant: FRAUNHOFER-GESELLSCHAFT ZUR FÖDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: Martin THOMA, Klaus FISCHER, Javier PORTILLO
  • METHOD FOR IRRADIATING A LIQUID WITH ACCELERATED ELECTRONS
    Publication number: 20190175769
    Abstract: Methods and Apparatus are provided for irradiating a liquid with accelerated electrons. The liquid is prepared. The liquid is mixed with particles having at least one luminescent substance, where the particles are formed such that the particles are dispersed in the liquid after mixing. The liquid is irradiated with an electromagnetic radiation, which induces the at least one luminescent substance to luminesce. An actual value of a physical quantity characterizing the luminescence of the luminescent substance is detected. The liquid is irradiated with accelerated electrons until the detected actual value corresponds to a target value.
    Type: Application
    Filed: June 8, 2017
    Publication date: June 13, 2019
    Applicant: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
    Inventors: Jessy SCHÖNFELDER, Frank-Holm RÖGNER, Javier PORTILLO CASADO, Jörg KUBUSCH