Abstract: An Unmanned Air Vehicle control station, comprising critical systems implementing safety involved functions, non-critical systems implementing non-safety involved functions and a gateway computer. The critical systems comprise at least two redundant critical computers, a redundant critical network and critical back-up network, and at least two redundant UAV-specific computers that implement UAV-specific functions and communicate with the UAV, wherein the at least two critical computers and the at least two UAV-specific computers are connected to the critical network and to the critical back-up network. The non-critical systems comprise at least one non-critical computer, and a non-critical network, wherein the at least one non-critical computer is connected to the non-critical network.

Abstract: The invention relates to a method for setting up a Remote Terminal Unit for social networking and to a Remote Terminal Unit. The Remote Terminal Unit having a configuration set (122) storing configuration data for a social network platform and participant set (123) storing a list of authorized participant accounts and participant permissions, and a dictionary set (124) storing requests, commands and associated tasks and task types. The RTU further has a controller (121) arranged for registering with the social network platform according to the configuration set (122), and creating and/or joining at least one participant group on the social network platform based on the participant set (123).

Abstract: An Unmanned Air Vehicle control station, comprising critical systems implementing safety involved functions, non-critical systems implementing non-safety involved functions and a gateway computer. The critical systems comprise at least two redundant critical computers, a redundant critical network and critical back-up network, and at least two redundant UAV-specific computers that implement UAV-specific functions and communicate with the UAV, wherein the at least two critical computers and the at least two UAV-specific computers are connected to the critical network and to the critical back-up network. The non-critical systems comprise at least one non-critical computer, and a non-critical network, wherein the at least one non-critical computer is connected to the non-critical network.

Abstract: Devices and methods are described that provide printing of three-dimensional objects using reactive materials such as materials that result in a polyurethane formulation. Three-dimensional printing in accordance with the present disclosure can be performed using an inkjet printer or other systems that deposit or dispense material. A formulation made up of two or more reactive materials and, optionally, one or more UV-curable materials is also provided. The materials can be jetted based on a desired configuration to achieve a maximum reaction between materials, and can be based on desired jetting or molar ratios. By heating or applying energy on the jetted materials, their reaction and related solidifying can be accelerated. Corrective printing is also provided for, and can be used at desired intervals to eliminate printing errors relative to the object as modeled. Systems and methods used in conjunction with all of the same are provided.

Abstract: The present invention provides novel triazatruxene derivatives that are useful as hole transport materials (HTM), particularly, in optoelectronic devices. The utility of the novel compounds was confirmed in solid-state, sensitized solar cells based on organic-inorganic perovskites used as light harvesters. The devices achieved high power conversion efficiencies.

Abstract: There is provided compounds of formula (I), wherein R1, R2, R3 and R4 have meanings given in the description (and which compounds are optionally substituted as indicated in the description), and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PIM family kinase, such as PIM-1, PIM-2 and/or PIM-3) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease. There is also provided combinations comprising the compounds of formula (I).

Abstract: There is provided compounds of formula (I), wherein A1, A4, A4a, A5, B1, B1a, B2, B2a, B3, B3a, B4, B4a and R3 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.

Abstract: System for reconstruction and visualization of cardiac electric activity, with high-resolution capabilities, which improves the performance of current systems by means of the inclusion of the a priori information of the bioelectric problem in a learning algorithm, and by means of the exploitation of the spatial and temporal correlations thanks to interpolation and decimation subsystems. The system consists of, at least: a plurality of catheters; ways for obtaining the location coordinates of said array; ways for obtaining the cardiac walls geometry; ways for processing the signals from the catheters, implementing an algorithm based on Support Vector Machines, allowing the incorporation of the bioelectric phenomena; ways of interpolation and redundance exploiting for yielding high resolution without matrix inversions; and ways of visualization.

Abstract: The measuring and processing unit (20) of the invention comprises an electrical bioimpedance measuring sub-unit (9) and a processing sub-unit (10) for the discrete processing of measurements including a memory element for storing the measurements. The modular electrical bioimpedance measuring, processing and monitoring system comprises at least one of the aforementioned bioimpedance measuring and processing units (20). The modular system allows transmitting measurements to an external unit (30), such as a computer or PDA, for processing and/or monitoring. The bioimpedance data can be transmitted over the Internet or a GSM network from the external unit (30) to a remote unit for remote monitoring.

Abstract: There is provided compounds of formula (I), wherein A1, A4, A4a, A5, B1, B1a, B2, B2a, B3, B3a, B4, B4a and R3 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.

Abstract: There is provided compounds of formula (I), wherein R1, R2, R3 and R4 have meanings given in the description (and which compounds are optionally substituted as indicated in the description), and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PIM family kinase, such as PIM-1, PIM-2 and/or PIM-3) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease. There is also provided combinations comprising the compounds of formula (I).

Abstract: System and method for the reconstruction of cardiac electrical activation from cardiac electrical signals recorded by intracardiac catheters. The obtained signals are processed using a Support Vector Machine (SVM) algorithm to solve the dual signal problem. Visualization of the solution includes geometric information in such a way that the cardiac electrical activity can be identified and localized. The system and method are described as a preferential application for anti-arrhythmic therapies.

Abstract: There is provided compounds of formula (I): wherein Z, M, R1, X, R3, R4 and R5 have meanings given in the description, an pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein kinase (e.g. a PIM family kinase or PI3-K) is desired and/or required, an particularly in the treatment of cancer.

Abstract: An event triggering an automatic real-time metric evaluation can be identified. A metric can be selected from one or more of metrics associated with the triggering event. Metric input can be collected from at least one source relevant to the selected metric. The collected metric input can be evaluated against one or more rules associated with the selected metric. The evaluation of the metric can be presented in real-time to an appropriate user. Based on the outcome of the evaluated metric, a programmatic action can be performed.

Abstract: Disclosed are methods of treating subjects having disorders or conditions characterized by an unwanted immune response including administering an effective amount of an early activation molecule agonist, antagonist or depletor, to the subject. Human monoclonal antibodies specific to the early activation molecules, and methods of use, are also disclosed.