Abstract: A middle-range (mid) low dropout (LDO) voltage has both sinking and sourcing current capability. The mid LDO can provide a voltage reference in active mode and power mode for core only design to work in a Safe Operating Area (SOA). The output of mid LDO can track IO power and/or core power dynamically. The mid LDO can comprise a voltage reference generator and a power-down controller connected to an amplifier, which output is connected to a decoupling capacitor. The provision of a high ground signal allows the mid LDO provide the sinking and sourcing currents.

Abstract: Provided is a method for preventing or treating a peripheral arterial occlusive disease (PAOD), including administering to a subject a CXC chemokine ligand 5 (CXCL5) antagonist in an effective amount. Also provided is a method for preventing or treating a peripheral ischemic tissue or a tissue damaged by peripheral ischemia through inhibition of CXCL5 to enhance angiogenesis, which may lead to an acceleration of wound healing.

Abstract: The preset invention relates to preventing, arresting, reversing or treating atherosclerosis, comprising a step of: administering to a subject in need thereof a therapeutically effective amount of a macrophage inflammatory protein-1 beta (MIP-1?) inhibitor.

Abstract: The present invention relates to a use of a macrophage inflammatory protein-1? (MIP-1?) inhibitor to protect the pancreas and prevent blood sugar from rising. The present invention relates to a use of a macrophage inflammatory protein-1? (MIP-1?) inhibitor to protect the pancreas, and to prevent blood sugar from rising in a diabetic subject.

Abstract: The present invention relates to a use of MIP-1? inhibitor for promoting angiogenesis in diabetes mellitus patients so as to improve tissue ischemia in damaged area and to prevent diabetic vasculopathy.

Abstract: Dextromethorphan is used to lower blood pressure in a subject suffering from hypertension, alone or in combination with another anti-hypertensive agent. In particular, dextromethorphan acts synergistically with a calcium channel blocker, such as amlodipine, to result in a major improvement in the treatment of hypertension, with no or little adverse effects.

Abstract: Dextromethorphan is used to lower blood pressure in a subject suffering from hypertension, alone or in combination with another anti-hypertensive agent. In particular, dextromethorphan acts synergistically with a calcium channel blocker, such as amlodipine, to result in a major improvement in the treatment of hypertension, with no or little adverse effects.

Abstract: Dextromethorphan is used to lower blood pressure in a subject suffering from hypertension, alone or in combination with another anti-hypertensive agent. In particular, dextromethorphan acts synergistically with a calcium channel blocker, such as amlodipine, to result in a major improvement in the treatment of hypertension, with no or little adverse effects.

Abstract: The lipoprotein lipase (LPL) gene is associated with hypertension, elevated plasma triglyceride and metabolic syndrome. A haplotype in the intron 3-intron 4 region (the C/AA/T haplotype), and a haplotype in the intron 5-intron 6 region (the GTAG haplotype), are particularly useful in predicting the risk of an individual for these medical conditions. In addition, other markers that display a linkage disequilibrium with either of these haplotypes can also be used in the same manner. The invention can be applied to Chinese, other Asian populations, Caucasian, African American, and other ethnic groups.