Patents by Inventor Jay Audett

Jay Audett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180256562
    Abstract: Described is a transdermal device comprising a backing layer; a single layer adhesive matrix comprising buprenorphine or a salt thereof, a pressure sensitive adhesive including a silicone-type adhesive blended with an acrylate-type adhesive, a solubilizer, a permeation enhancer, and a crystallization inhibitor; and a release layer. Also described is a method of relieving pain and a method of preparing a transdermal delivery system.
    Type: Application
    Filed: September 9, 2016
    Publication date: September 13, 2018
    Inventors: Sameer Sachdeva, Tarun Goswami, Jay Audett
  • Publication number: 20180235903
    Abstract: Described is a transdermal device comprising a backing layer; an adhesive matrix comprising fentanyl as an active agent suspended on a plurality of pressure sensitive adhesives along with a cross-linked moisture absorbent comprising cross-linked polyvinylpyrrolidone; and a release layer. Also described is a method of relieving pain, which comprising applying said transdermal device to the skin of a patient in need thereof.
    Type: Application
    Filed: March 11, 2016
    Publication date: August 23, 2018
    Inventors: Jay Audett, Chee Youb Won
  • Publication number: 20160374955
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Application
    Filed: September 13, 2016
    Publication date: December 29, 2016
    Applicant: ALZA Corporation
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J.N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Patent number: 9446004
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: September 20, 2016
    Assignee: ALZA CORPORATION
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J. N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Publication number: 20160051488
    Abstract: A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
    Type: Application
    Filed: October 30, 2015
    Publication date: February 25, 2016
    Inventors: Jay Audett, Jianye Wen, Eli J. Goldman, Robert M. Gale, Allison Luciano, Paul B. Foreman, Eric N. Silverberg
  • Patent number: 9205090
    Abstract: A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: December 8, 2015
    Assignee: ALZA Corporation
    Inventors: Jay Audett, Jianye Wen, Eli J. Goldman, Robert M. Gale, Allison Luciano, Paul B. Foreman, Eric N. Silverberg
  • Publication number: 20150246007
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Application
    Filed: May 18, 2015
    Publication date: September 3, 2015
    Applicant: ALZA Corporation
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J.N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Patent number: 9056061
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: June 16, 2015
    Assignee: ALZA Corporation
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J. N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Publication number: 20140249125
    Abstract: A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
    Type: Application
    Filed: May 9, 2014
    Publication date: September 4, 2014
    Applicant: ALZA Corporation
    Inventors: Jay Audett, Jianye Wen, Eli J. Goldman, Robert M. Gale, Allison Luciano, Paul B. Foreman, Eric N. Silverberg
  • Patent number: 8758808
    Abstract: A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: June 24, 2014
    Assignee: ALZA Corporation
    Inventors: Jay Audett, Jianye Wen, Eli J. Goldman, Robert M. Gale, Allison Luciano, Paul B. Foreman, Eric N. Silverberg
  • Patent number: 8747889
    Abstract: A transdermal analgesic system having reduced potential for abuse, wherein the system provides for the controlled release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the dosage form is subject to abuse is disclosed.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: June 10, 2014
    Assignee: Durect Corporation
    Inventors: Robert M. Gale, Thomas M. Stein, Jay Audett, Jane Stepic, Joseph B. Phipps, Michael J. N. Cormier
  • Publication number: 20130251760
    Abstract: A transdermal analgesic system having reduced potential for abuse, wherein the system provides for the controlled release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the dosage form is subject to abuse is disclosed.
    Type: Application
    Filed: March 7, 2013
    Publication date: September 26, 2013
    Inventors: Robert M. Gale, Thomas M. Stien, Jay Audett, Jane Stepic, Joseph B. Phipps, Michael JN Cormier
  • Patent number: 8440220
    Abstract: A transdermal analgesic system having reduced potential for abuse, wherein the system provides for the controlled release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the dosage form is subject to abuse is disclosed.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: May 14, 2013
    Assignee: Durect Corporation
    Inventors: Robert M. Gale, Thomas M. Stein, Jay Audett, Jane Stepic, Joseph B. Phipps, Michel J. N. Cormier
  • Patent number: 8383149
    Abstract: A polyacrylate formulation suitable for delivery of drug through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: February 26, 2013
    Assignee: ALZA Corporation
    Inventors: Jay Audett, Jianye Wen, Eli J. Goldman, Robert M. Gale, Allison Luciano, Paul B. Foreman, Eric N. Silverberg
  • Publication number: 20070281027
    Abstract: A novel backing construction for a transdermal drug delivery system is disclosed. In particular, the invention relates to a system and method for labeling a transdermal drug delivery system, wherein the backing layer contains a writable medium capable of inkless printing.
    Type: Application
    Filed: August 20, 2007
    Publication date: December 6, 2007
    Inventor: Jay Audett
  • Publication number: 20070104771
    Abstract: A transdermal galantamine delivery system to an individual. The system has a high galantamine loading with suitable permeation enhancers to effect therapeutic flux rate. Acrylate polymeric reservoir with the high galantamine and permeation enhancers dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties for multiple-day delivery.
    Type: Application
    Filed: September 22, 2006
    Publication date: May 10, 2007
    Inventors: Jay Audett, Eli Goldman, Delphine Imbert, Diane Nedberge, Jianye Wen, Allison Luciano, Eric Silverberg, Paul Foreman, Johan Geerke
  • Publication number: 20070098772
    Abstract: A system for transdermal delivery of norelgestromin (NGMN) to an individual. The system has a high NGMN loading with suitable permeation enhancers to effect therapeutic flux rate. Polyacrylate drug reservoir with the NGMN and high loading of one or more of permeation enhancers and NGMN dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties. Estrogen can be delivered with the NGMN.
    Type: Application
    Filed: September 22, 2006
    Publication date: May 3, 2007
    Inventors: Tyler Westcott, Jane Stepic, Delphine Imbert, Jay Audett, Jianye Wen, Allison Luciano, Eric Silverberg, Paul Foreman
  • Publication number: 20070098771
    Abstract: A polyacrylate formulation suitable for delivery of drug to through a body surface of an individual. By loading the drug and permeation enhancers at a high concentration into a polyacrylate proadhesive that has inadequate adhesive properties for typical adhesive application on the skin, a formulation with desirable adhesive characteristics and effective therapeutic properties can be made. The proadhesive has higher glass transition temperature than typical pressure sensitive adhesives.
    Type: Application
    Filed: September 22, 2006
    Publication date: May 3, 2007
    Inventors: Jay Audett, Jianye Wen, Eli Goldman, Robert Gale, Allison Luciano, Paul Foreman, Eric Silverberg
  • Publication number: 20070082038
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Application
    Filed: September 22, 2006
    Publication date: April 12, 2007
    Inventors: Robert Gale, Jay Audett, Rama Padmanabhan, Michel Cormier, Allison Luciano, Eric Silverberg, Paul Foreman
  • Publication number: 20050095279
    Abstract: A transdermal analgesic system having reduced potential for abuse, wherein the system provides for the controlled release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the dosage form is subject to abuse is disclosed.
    Type: Application
    Filed: October 27, 2004
    Publication date: May 5, 2005
    Inventors: Robert Gale, Thomas Stein, Jay Audett