Abstract: A method of hermetically bonding components of an implantable pump made of biocompatible materials comprises the steps of providing a first SiO2 layer of predetermined first thickness onto a selected bonding surface of a first biocompatible component of the implantable pump to reduce the surface roughness, Ra, available for bonding below a first predetermined magnitude; providing a second SiO2 layer of predetermined second thickness onto a selected bonding surface of a second biocompatible component of the implantable pump to reduce the surface roughness of the selected bonding surface; and bringing the first and second SiO2 layers into contact with each other at a low temperature with a low pressure to form a high quality hermetic bond and seal between first and second SiO2 layers. The invention includes an implantable pump having a hermetic seal manufactured by the method.